scholarly journals Novel Natural Polymer/Medicinal Plant Extract Electrospun Nanofiber for Cosmeceutical Application

10.5772/63412 ◽  
2016 ◽  
Author(s):  
Jeong Hyun Yeum ◽  
Sung Min Park ◽  
Seong Baek Yang ◽  
Yeasmin Sabina ◽  
Young Hun Kim ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Plant Extract ◽  
Natural Polymer ◽  
Electrospun Nanofiber

Elaeagnus Angustifolia: a Promising Medicinal Plant for Cancer Theraby

2020 ◽  
Author(s):  
Islam Mohamed ◽  
Ahmed Moahmed ◽  
Mennatallah Abdelkader ◽  
Alaaeldin Saleh ◽  
Ala-Eddin Al-Moustafa
Keyword(s):  
Cell Proliferation ◽  
Oral Cancer ◽  
Medicinal Plant ◽  
Cancer Progression ◽  
Plant Extract ◽  
Cell Invasion ◽  
Elaeagnus Angustifolia ◽  
Flower Extract ◽  
Inhibition Of Angiogenesis ◽  
E Cadherin

Introduction: Elaeagnus angustifolia (EA) is a medicinal plant that has been used for centuries in treating many human diseases, in the Middle East, including fever, amoebic dysentery, gastrointestinal problems. However, the effect of EA plant extract on human cancer progression especially oral malignancy has not been investigated yet. Thus, first we examined the effect of EA flower extract on angiogenesis in ovo, and on selected parameters in human oral cancer cells. Materials and methods: Chorioallantoic membranes (CAMs) of chicken embryos at 3-7 days of incubation were used to assess the effect EAflower plant extract on angiogenesis. Meanwhile, cell proliferation, soft agar, cell cycle, cell invasion and cell wounding assays were performed to explore the outcome of EA plant extract on FaDu and SCC25 oral cancer cell lines. On the other hand, western blot analysis was carried out to evaluate E-cadherin and Erk1/Erk2 expression and activation, respectively, in FaDu and SCC25 under the effect of EA extract. Results: Our data show that EA extract inhibits cell proliferation and colony formation, in addition to the initiation of Scell cycle arrest and reductionof G1/G2 phases. In parallel, EA extract provokes differentiation to an epithelial phenotype “mesenchymal-epithelial transition: MET” which is the opposite of “epithelial-mesenchymal transition, EMT”: an important event in cell invasion and metastasis. Thus, EA extract causes a dramatic decrease in cell motility and invasion abilities of FaDu and SCC25 cancer cells in comparison with their controls. These changes are accompanied by an up-regulation of E-cadherin expression. The molecular pathway analysis of the EA flower extract reveals that it can inhibit the phosphorylation of Erk1/Erk2, which could be behind the inhibition of angiogenesis, the initiation of MET event and the overexpression of E-cadherin. Conclusions: Our findings indicate that EA plant extract can downgrade human oral cancer progression by the inhibition of angiogenesis and cell invasion via Erk1/Erk2 signaling pathways.

scholarly journals Isolation, Structure Elucidation, and Biological Activity of a New Alkaloid from Zanthoxylum rhetsa

2011 ◽  
Vol 6 (11) ◽  
pp. 1934578X1100601
Author(s):  
Karsten Krohn ◽  
Stephan Cludius-Brandt ◽  
Barbara Schulz ◽  
Mambatta Sreelekha ◽  
Pottachola Mohamed Shafi
Keyword(s):  
Biological Activity ◽  
Carboxylic Acid ◽  
Medicinal Plant ◽  
Plant Extract ◽  
Structure Elucidation ◽  
Biologically Active ◽  
Reduction Product ◽  
Pharmacological Properties ◽  
Evergreen Tree

Several biologically active alkaloids (1-4, 6), including a new quinazoline-6-carboxylic acid (1), were isolated from the medicinal plant Zanthoxylum rhetsa, an evergreen tree, native to subtropical areas. Whereas the pharmacological properties of the plant extract and single constituents have been widely tested, we now show that all of the metabolites have antialgal activities, all but 6 are antibacterial, and 6 and the reduction product 5 (derived from 4) are also antifungal.

Effects of the folk medicinal plant extract Ankaferd Blood Stopper®on the ocular surface

2011 ◽  
Vol 30 (4) ◽  
pp. 280-285 ◽  
Author(s):  
Atilla Alpay ◽  
Cenk Evren ◽  
Sibel Bektaş ◽  
Sılay Canturk Ugurbas ◽  
Suat Hayri Ugurbas ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Plant Extract ◽  
Ocular Surface ◽  
Ankaferd Blood Stopper

scholarly journals Effect of Medicinal Plant Extract Incorporated Carrageenan Based Films on Shelf-Life of Chicken Breast Meat

2013 ◽  
Vol 33 (1) ◽  
pp. 53-57 ◽  
Author(s):  
Kuk-Hwan Seol ◽  
Beom-Jin Joo ◽  
Hyoun Wook Kim ◽  
Oun-Ki Chang ◽  
Jun-Sang Ham ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Shelf Life ◽  
Plant Extract ◽  
Chicken Breast ◽  
Breast Meat ◽  
Chicken Breast Meat

scholarly journals In Vivo Hemostatic Effect of the Medicinal Plant Extract Ankaferd Blood Stopper in Rats Pretreated With Warfarin

2008 ◽  
Vol 15 (3) ◽  
pp. 270-276 ◽  
Author(s):  
Handan S. Cipil ◽  
Ali Kosar ◽  
Arif Kaya ◽  
Burak Uz ◽  
Ibrahim C. Haznedaroglu ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Plant Extract ◽  
Hemostatic Effect ◽  
Ankaferd Blood Stopper

scholarly journals Hemostatic Efficacy of a Traditional Medicinal Plant Extract (Ankaferd Blood Stopper) in Bleeding Control

2013 ◽  
Vol 21 (4) ◽  
pp. 348-353 ◽  
Author(s):  
Ozgur Sogut ◽  
Mehmet Ozgur Erdogan ◽  
Rustu Kose ◽  
Mehmet Emin Boleken ◽  
Halil Kaya ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Plant Extract ◽  
Bleeding Control ◽  
Ankaferd Blood Stopper ◽  
Hemostatic Efficacy
Sign in / Sign up

Export Citation Format

Share Document