scholarly journals Dealing with the Data Deluge – New Strategies in Prokaryotic Genome Analysis

10.5772/62125 ◽  
2016 ◽  
Author(s):  
Leonid Zaslavsky ◽  
Stacy Ciufo ◽  
Boris Fedorov ◽  
Boris Kiryutin ◽  
Igor Tolstoy ◽  
...  
Keyword(s):  
Genome Analysis ◽  
Prokaryotic Genome ◽  
New Strategies

scholarly journals Explainability in transformer models for functional genomics

2021 ◽  
Author(s):  
Jim Clauwaert ◽  
Gerben Menschaert ◽  
Willem Waegeman
Keyword(s):  
Functional Genomics ◽  
Dna Sequences ◽  
Prokaryotic Genome ◽  
Learning Methods ◽  
New Approach ◽  
Consensus Sequences ◽  
Automated Learning ◽  
Transcription Process ◽  
New Strategies ◽  
Selection Of

Abstract The effectiveness of deep learning methods can be largely attributed to the automated extraction of relevant features from raw data. In the field of functional genomics, this generally concerns the automatic selection of relevant nucleotide motifs from DNA sequences. To benefit from automated learning methods, new strategies are required that unveil the decision-making process of trained models. In this paper, we present a new approach that has been successful in gathering insights on the transcription process in Escherichia coli. This work builds upon a transformer-based neural network framework designed for prokaryotic genome annotation purposes. We find that the majority of subunits (attention heads) of the model are specialized towards identifying transcription factors and are able to successfully characterize both their binding sites and consensus sequences, uncovering both well-known and potentially novel elements involved in the initiation of the transcription process. With the specialization of the attention heads occurring automatically, we believe transformer models to be of high interest towards the creation of explainable neural networks in this field.

CDC Pushing New Strategies for Flu Vaccination

2006 ◽  
Vol 40 (11) ◽  
pp. 12
Author(s):  
HEIDI SPLETE
Keyword(s):  
Flu Vaccination ◽  
New Strategies

The Coin of the African Realm

2017 ◽  
Author(s):  
Jeffrey Herbst
Keyword(s):  
Twentieth Century ◽  
West Africa ◽  
West African ◽  
Regional Economies ◽  
African Countries ◽  
New Strategies

This chapter examines the politics of the currency in West Africa from the beginning of the twentieth century. A public series of debates over the nature of the currency occurred in West Africa during both the colonial and independence periods. Since 1983, West African countries have been pioneers in Africa in developing new strategies to combat overvaluation of the currency and reduce the control of government over the currency supply. The chapter charts the evolution of West African currencies as boundaries and explores their relationship to state consolidation. It shows that leaders in African capitals managed to make the units they ruled increasingly distinct from the international and regional economies, but the greater salience of the currency did not end up promoting state consolidation. Rather, winning the ability to determine the value of the currency led to a series of disastrous decisions that severely weakened the states themselves.

Internationalization in Higher Education in Russia: Challenges, Lessons and Prospects of Collaboration with Vietnam

2017 ◽  
Vol 33 (2) ◽  
Author(s):  
Natalia Kraevskaia
Keyword(s):  
Higher Education ◽  
Education Reform ◽  
Knowledge Production ◽  
Professional Training ◽  
National Interests ◽  
International Networks ◽  
International Dimension ◽  
Main Factors ◽  
Internationalization In Higher Education ◽  
New Strategies

The article addresses the needs of educational system in context of rapidly developing globalization and explores internationalization of higher education as one of the main factors which contributes to integration of international dimension to professional training at universities. Different components and strategies of internationalization, such as strong collaboration in teaching, internationalization of the curriculum, cooperation in researches and knowledge production, students and professors’ mobility, and participation in international networks are analyzed in connection to education reform in Russia. The article provides the comparison of internationalization policies in Russian and Vietnamese education systems, argues that innovations in higher education should be adjusted to the national interests, traditions and mentality and finally describes new strategies in collaboration of Russia and Vietnam in the field of education.  

Sign in / Sign up

Export Citation Format

Share Document