scholarly journals A Concise Review of Autoimmune Liver Diseases

10.5772/60520 ◽  
2015 ◽  
Author(s):  
Nwe Ni Than ◽  
Ye Htun Oo
Keyword(s):  
Liver Diseases ◽  
Autoimmune Liver Diseases ◽  
Concise Review

scholarly journals Current Trends and Characteristics of Hepatocellular Carcinoma in Patients with Autoimmune Liver Diseases

Cancers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1023
Author(s):  
Eirini I. Rigopoulou ◽  
George N. Dalekos
Keyword(s):  
Risk Factors ◽  
Hepatocellular Carcinoma ◽  
Liver Diseases ◽  
Treatment Modalities ◽  
Primary Biliary Cholangitis ◽  
Autoimmune Liver Diseases ◽  
Increased Risk ◽  
Liver Cancers ◽  
Medium Risk ◽  
Causes Of Mortality

Hepatocellular carcinoma (HCC), the commonest among liver cancers, is one of the leading causes of mortality among malignancies worldwide. Several reports demonstrate autoimmune liver diseases (AILDs), including autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC) to confer increased risk of hepatobiliary malignancies, albeit at lower frequencies compared to other liver diseases. Several parameters have been recognized as risk factors for HCC development in AIH and PBC, including demographics such as older age and male sex, clinical features, the most decisive being cirrhosis and other co-existing factors, such as alcohol consumption. Moreover, biochemical activity and treatment response have been increasingly recognized as prognostic factors for HCC development in AIH and PBC. As available treatment modalities are effective only when HCC diagnosis is established early, surveillance has been proven essential for HCC prognosis. Considering that the risk for HCC is not uniform between and within disease groups, refinement of screening strategies according to prevailing demographic, clinical, and molecular risk factors is mandated in AILDs patients, as personalized HCC risk prediction will offer significant advantage in patients at high and/or medium risk. Furthermore, future investigations should draw attention to whether modification of immunosuppression could benefit AIH patients after HCC diagnosis.

Histological recurrence of autoimmune liver diseases after living-donor liver transplantation

2007 ◽  
Vol 37 (s3) ◽  
pp. S463-S469 ◽  
Author(s):  
Hironori Haga ◽  
Aya Miyagawa-Hayashino ◽  
Kaoru Taira ◽  
Daisuke Morioka ◽  
Hiroto Egawa ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Diseases ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Autoimmune Liver Diseases

The Association of Two Rare Diseases is Not Rare: Primary Immunodeficiencies and Autoimmune Liver Diseases

2021 ◽  
Author(s):  
Şefika Nur Ayar ◽  
Elif Soyak ◽  
Cem Şimşek ◽  
Deniz Çağdaş ◽  
Yasemin Balaban
Keyword(s):  
Rare Diseases ◽  
Liver Diseases ◽  
Strong Association ◽  
Laboratory Data ◽  
Tertiary Hospital ◽  
Iga Deficiency ◽  
Primary Biliary Cholangitis ◽  
Cross Sectional ◽  
Autoimmune Liver Diseases ◽  
Igm Deficiency

Abstract Purpose: PIDs associates with autoimmune diseases include autoimmune liver diseases (AILD); however, the frequency of PIDs among patients with AILD is unknown. This study aimed to evaluate the strength of the association between AILD and PIDs. Methods: We conducted this single-center, cross-sectional, and descriptive study in a tertiary hospital. We evaluated eighty-two patients with AILD (39 autoimmune hepatitis (AIH), 32 with primary biliary cholangitis (PBC), seven with variant syndromes (VS), and four with primary sclerosing cholangitis (PSC) for the presence of PIDs. We obtained a detailed history of infections, comorbidities, family history, and laboratory data from the files. All patients were evaluated in the immunology department for further examination, and PID diagnoses were made according to ESID (The European Society for Immunodeficiencies) criteria. Results: Out of 82 patients with AILD, PIDs were diagnosed in 18% (15 patients); there were four patients with common variable immunodeficiency (CVID), four with partial IgA deficiency (PIgAD), four with selective IgM deficiency (SIgMD), and three with combined immunodeficiency (CID). PIDs were present in 29% of patients with VS, 25 % of patients with PSC, 23% of patients with AIH, and 9% of patients with PBC. Conclusion: Although PIDs are rare diseases in the general population, they have a strong association with AILD and were detected in one-fifth of the patients. Further research with larger patient groups is needed to evaluate the diagnostic and prognostic impacts of PIDs on AILD.

Pediatric Autoimmune Liver Diseases

2021 ◽  
Vol 68 (6) ◽  
pp. 1293-1307
Author(s):  
Sarah Kemme ◽  
Cara L. Mack
Keyword(s):  
Liver Diseases ◽  
Autoimmune Liver Diseases

Evaluation of non organ specific autoantibodies in children transplanted for non-autoimmune liver diseases

2001 ◽  
Vol 120 (5) ◽  
pp. A213-A214 ◽  
Author(s):  
Maria G. Clemente ◽  
Pietro Vajro ◽  
Maria P. Musu ◽  
Eduardo Ciccimarra ◽  
Claudia Mandato ◽  
...  
Keyword(s):  
Liver Diseases ◽  
Autoimmune Liver Diseases ◽  
Organ Specific

Genetics of Autoimmune Liver Diseases

2020 ◽  
pp. 69-85
Author(s):  
Alessio Gerussi ◽  
Marco Carbone ◽  
Rosanna Asselta ◽  
Pietro Invernizzi
Keyword(s):  
Liver Diseases ◽  
Autoimmune Liver Diseases

Geoepidemiology of Autoimmune Liver Diseases

2020 ◽  
pp. 167-178
Author(s):  
Zhuwan Lyu ◽  
M. Eric Gershwin ◽  
Xiong Ma
Keyword(s):  
Liver Diseases ◽  
Autoimmune Liver Diseases
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