scholarly journals Ocular Aberrations and Image Quality, Contact Lens and MYOPIA Progression

Author(s):  
Jie Shen
2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Marcus Ang ◽  
Yijun Cai ◽  
Anna C. S. Tan

Purpose. To describe a novel technique of adapting a swept-source optical coherence tomography angiography (OCTA) to image corneal vascularization.Methods. In this pilot cross-sectional study, we obtained 3 × 3 mm scans, where 100,000 A-scans are acquired per second with optical axial resolution of 8 μm and lateral resolution of 20 μm. This was performed with manual “XYZ” focus without the anterior segment lens, until the focus of the corneoscleral surface was clearly seen and the vessels of interest were in focus on the corresponding red-free image. En face scans were evaluated based on image quality score and repeatability.Results. We analyzed scans from 10 eyes (10 patients) with corneal vascularization secondary to contact lens use in 4 quadrants, with substantial repeatability of scans in all quadrants (mean image quality score 2.7 ± 0.7;κ=0.75). There was no significant difference in image quality scores comparing quadrants (superior temporal: 2.9 ± 0.6, superior nasal: 2.8 ± 0.4, inferior temporal: 2.5 ± 0.9, and inferior nasal: 2.4 ± 1.0;P=0.276) and able to differentiate deep and superficial corneal vascularization.Conclusion. This early clinical study suggests that the swept-source OCTA used may be useful for examining corneal vascularization, which may have potential for clinical applications such as detecting early limbal stem cell damage.


2014 ◽  
Vol 34 (3) ◽  
pp. 331-345 ◽  
Author(s):  
Arthur Bradley ◽  
Jayoung Nam ◽  
Renfeng Xu ◽  
Leslie Harman ◽  
Larry Thibos

2009 ◽  
Vol 86 (10) ◽  
pp. 1150-1153 ◽  
Author(s):  
Adam Blacker ◽  
G Lynn Mitchell ◽  
Mark A. Bullimore ◽  
Bill Long ◽  
Joseph T. Barr ◽  
...  

Author(s):  
Jeffrey J. Walline ◽  
Donald O. Mutti ◽  
Karla Zadnik

2001 ◽  
Vol 78 (4) ◽  
pp. 223-233 ◽  
Author(s):  
Jeffrey J. Walline ◽  
Donald O. Mutti ◽  
Lisa A. Jones ◽  
Marjorie J. Rah ◽  
Kelly K. Nichols ◽  
...  

2018 ◽  
Author(s):  
Ian G Beasley ◽  
Leon N Davies ◽  
Nicola S Logan

BACKGROUND Hyperopia occurs due to insufficient ocular growth and a failure to emmetropize in childhood. In anisohyperopia, it is unclear why one eye may remain hyperopic while the fellow eye grows toward an emmetropic state. Animal studies have shown that manipulating peripheral defocus through optical means while simultaneously providing correct axial focus can either discourage or encourage axial eye growth to effectively treat myopia or hyperopia, respectively. Myopia progression and axial eye growth can be significantly reduced in children and adolescents through the use of multifocal contact lenses. These contact lenses correct distance central myopia while simultaneously imposing relative peripheral myopic defocus. The effect of correcting distance central hyperopia while simultaneously imposing relative peripheral hyperopic defocus is yet to be elucidated in humans. OBJECTIVE The objective of our study is to understand the natural progression of axial eye growth and refractive error in hyperopes and anisohyperopes and to establish whether axial eye growth and refractive error can be modified using multifocal contact lenses in hyperopes and anisohyperopes. METHODS There are 3 elements to the program of research. First, the natural progression of axial eye growth and refractive error will be measured in spectacle-wearing hyperopic and anisohyperopic subjects aged between 5 and <20 years. In other words, the natural growth of the eye will be followed without any intervention. Second, as a paired-eye control study, anisohyperopes aged between 8 and <16 years will be fitted with a center-near multifocal design contact lens in their more hyperopic eye and a single-vision contact lens in the fellow eye if required. The progression of axial eye growth and refractive error will be measured and compared. Third, subjects aged between 8 and <16 years with similar levels of hyperopia in each eye will be fitted with center-near multifocal design contact lenses in each eye; the progression of axial eye growth and refractive error in these subjects will be measured and compared with those of subjects in the natural progression study. RESULTS Recruitment commenced on 6 June 2016 and was completed on 8 April 2017. We estimate the data collection to be completed by April 2020. CONCLUSIONS This trial will establish whether axial eye growth can be accelerated in children with hyperopia by imposing relative peripheral hyperopic defocus using center-near multifocal contact lenses. CLINICALTRIAL ClinicalTrials.gov NCT02686879; https://clinicaltrials.gov/ct2/show/NCT02686879 (Archived by Webcite at http://www.webcitation.org/71o5p3fD2) REGISTERED REPORT IDENTIFIER RR1-10.2196/9320


Sign in / Sign up

Export Citation Format

Share Document