scholarly journals Prospects of ‘Omics Based Molecular Approaches in Colorectal Cancer Diagnosis and Treatment in the Developing World: A Case Study in Cape Town, South Africa

10.5772/57485 ◽  
2014 ◽  
Author(s):  
Henry Adeola ◽  
Ryan William ◽  
Paul Goldberg ◽  
Jonathan Blackbur
Keyword(s):  
Colorectal Cancer ◽  
South Africa ◽  
Cancer Diagnosis ◽  
Developing World ◽  
Cape Town ◽  
Diagnosis And Treatment ◽  
Molecular Approaches

scholarly journals Microbial Metabolites in Colorectal Cancer: Basic and Clinical Implications

Metabolites ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 159
Author(s):  
Yao Peng ◽  
Yuqiang Nie ◽  
Jun Yu ◽  
Chi Chun Wong
Keyword(s):  
Colorectal Cancer ◽  
Gut Microbiota ◽  
Cancer Diagnosis ◽  
Intestinal Tract ◽  
Clinical Applications ◽  
Diagnosis And Treatment ◽  
Clinical Implications ◽  
Microbial Metabolites ◽  
Colorectal Tumorigenesis ◽  
Technology Studies

Colorectal cancer (CRC) is one of the leading cancers that cause cancer-related deaths worldwide. The gut microbiota has been proved to show relevance with colorectal tumorigenesis through microbial metabolites. By decomposing various dietary residues in the intestinal tract, gut microbiota harvest energy and produce a variety of metabolites to affect the host physiology. However, some of these metabolites are oncogenic factors for CRC. With the advent of metabolomics technology, studies profiling microbiota-derived metabolites have greatly accelerated the progress in our understanding of the host-microbiota metabolism interactions in CRC. In this review, we briefly summarize the present metabolomics techniques in microbial metabolites researches and the mechanisms of microbial metabolites in CRC pathogenesis, furthermore, we discuss the potential clinical applications of microbial metabolites in cancer diagnosis and treatment.

scholarly journals An Approach to Developing a Prediction Model of Fertility Intent Among HIV-Positive Women and Men in Cape Town, South Africa: A Case Study

2016 ◽  
Vol 21 (2) ◽  
pp. 597-609 ◽  
Author(s):  
Dan Bai ◽  
Cheng-Shiun Leu ◽  
Joanne E. Mantell ◽  
Theresa M. Exner ◽  
Diane Cooper ◽  
...  
Keyword(s):  
South Africa ◽  
Prediction Model ◽  
Cape Town ◽  
Hiv Positive ◽  
Hiv Positive Women

scholarly journals The ongoing challenge of restorative justice in South Africa: How and why wealthy suburban congregations are responding to poverty and inequality

2014 ◽  
Vol 70 (2) ◽  
Author(s):  
Nadine F. Bowers du Toit ◽  
Grace Nkomo
Keyword(s):  
South Africa ◽  
Restorative Justice ◽  
Cape Town ◽  
Lay Leaders ◽  
Poverty And Inequality ◽  
The World ◽  
Basic Features

South Africa remains one of the most unequal societies in the world and any discussion around poverty and the church’s response cannot exclude this reality. This article attempts to analyse the response of wealthy, ‘majority white’ suburban congregations in the southern suburbs of Cape Town to issues of poverty and inequality. This is attempted through the lense of restorative justice, which is broadly explored and defined through a threefold perspective of reconciliation, reparations and restitution. The first part explores a description of the basic features of poverty and inequality in South Africa today, followed by a discussion on restorative justice. This is followed by the case study, which gives the views of clergy and lay leaders with regard to their congregations’ perspectives and responses to poverty and inequality within the context of restorative justice. Findings from the case study begin to plot a tentative ‘way forward’ as to how our reality can more constructively be engaged from the perspective of congregational involvement in reconstruction of our society.

Impact of cancer diagnosis and treatment on glycaemic control among individuals with colorectal cancer using glucose-lowering drugs

2016 ◽  
Vol 53 (5) ◽  
pp. 727-735 ◽  
Author(s):  
Marjolein M. J. Zanders ◽  
Myrthe P. P. van Herk-Sukel ◽  
Ron M. C. Herings ◽  
Lonneke V. van de Poll-Franse ◽  
Harm R. Haak
Keyword(s):  
Colorectal Cancer ◽  
Glycaemic Control ◽  
Cancer Diagnosis ◽  
Diagnosis And Treatment ◽  
Glucose Lowering
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