scholarly journals Curative Radiotherapy in Metastatic Disease: How to Develop the Role of Radiotherapy from Local to Metastases

10.5772/56556 ◽  
2013 ◽  
Author(s):  
Chul-Seung Kay ◽  
Young-Nam Kang
Keyword(s):  
Metastatic Disease ◽  
Curative Radiotherapy

scholarly journals Diagnostic Role of 18F-PSMA-1007 PET/CT in Prostate Cancer Staging: A Systematic Review

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 552
Author(s):  
Salam Awenat ◽  
Arnoldo Piccardo ◽  
Patricia Carvoeiras ◽  
Giovanni Signore ◽  
Luca Giovanella ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Systematic Review ◽  
Diagnostic Accuracy ◽  
Metastatic Disease ◽  
Cancer Staging ◽  
Relevant Information ◽  
Cochrane Library ◽  
Number Of Patients ◽  
Pet Ct

Background: The use of prostate-specific membrane antigen (PSMA)-targeted agents for staging prostate cancer (PCa) patients using positron emission tomography/computed tomography (PET/CT) is increasing worldwide. We performed a systematic review on the role of 18F-PSMA-1007 PET/CT in PCa staging to provide evidence-based data in this setting. Methods: A comprehensive computer literature search of PubMed/MEDLINE and Cochrane Library databases for studies using 18F-PSMA-1007 PET/CT in PCa staging was performed until 31 December 2020. Eligible articles were selected and relevant information was extracted from the original articles by two authors independently. Results: Eight articles (369 patients) evaluating the role of 18F-PSMA-1007 PET/CT in PCa staging were selected. These studies were quite heterogeneous, but, overall, they demonstrated a good diagnostic accuracy of 18F-PSMA-1007 PET/CT in detecting PCa lesions at staging. Overall, higher primary PCa aggressiveness was associated with higher 18F-PSMA-1007 uptake. When compared with other radiological and scintigraphic imaging methods, 18F-PSMA-1007 PET/CT had superior sensitivity in detecting metastatic disease and the highest inter-reader agreement. 18F-PSMA-1007 PET/CT showed similar results in terms of diagnostic accuracy for PCa staging compared with PET/CT with other PSMA-targeted tracers. Dual imaging with multi-parametric magnetic resonance imaging and 18F-PSMA-1007 PET/CT may improve staging of primary PCa. Notably, 18F-PSMA-1007-PET/CT may detect metastatic disease in a significant number of patients with negative standard imaging. Conclusions: 18F-PSMA-1007 PET/CT demonstrated a good accuracy in PCa staging, with similar results compared with other PSMA-targeted radiopharmaceuticals. This method could substitute bone scintigraphy and conventional abdominal imaging for PCa staging. Prospective multicentric studies are needed to confirm these findings.

scholarly journals Role of Radiotherapy in Recurrent Intra-Abdominal Yolk Sac Tumor

2021 ◽  
pp. 1010-1018
Author(s):  
Marhendra Satria Utama ◽  
Andi Kurniadi ◽  
A.A. Citra Yunda Prahastiwi ◽  
Antony A. Adibrata
Keyword(s):  
Case Reports ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Appropriate Treatment ◽  
Curative Radiotherapy ◽  
Chief Complaints ◽  
Abdominal Mri ◽  
Malignant Germ Cell Tumor

Yolk sac tumor (YST) is a rare malignant germ cell tumor with no appropriate treatment strategy to date. However, patients are treated on a case-to-case basis as per various case reports that have been published. Here, we present a case of 27-year-old female patient who presented to us with chief complaints of severe abdominal pain associated with leucorrhea. She previously had a similar pain episode, which was then evaluated by a multidisciplinary team. She was diagnosed with YST. After that, she underwent 6 cycles of chemotherapy, but there was no improvement. Then the medical oncologist referred her to performed radiotherapy. Then, the radiation oncologist decided to give her curative radiotherapy of 3D-CRT. After completing her sessions, she felt better and clinically improving. After that, she was discharged and scheduled a follow-up visit for first evaluation. At her follow-up visit, she was feeling well, and we decided to have an abdominal MRI.

scholarly journals Role of Runx2 phosphorylation in prostate cancer and association with metastatic disease

Oncogene ◽  
2015 ◽  
Vol 35 (3) ◽  
pp. 366-376 ◽  
Author(s):  
C Ge ◽  
G Zhao ◽  
Y Li ◽  
H Li ◽  
X Zhao ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Metastatic Disease

scholarly journals ERRATUM: Role of Chemotherapy in Stage II Nasopharyngeal Carcinoma Treated with Curative Radiotherapy

2016 ◽  
Vol 48 (1) ◽  
pp. 425-425
Author(s):  
Min Kyu Kang ◽  
Dongryul Oh ◽  
Kwan Ho Cho ◽  
Sung Ho Moon ◽  
Hong-Gyun Wu ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Stage Ii ◽  
Curative Radiotherapy

Role of Surgery for Locally Advanced and Metastatic Renal Cell Carcinoma

2011 ◽  
Vol 9 (9) ◽  
pp. 985-993 ◽  
Author(s):  
Robert Torrey ◽  
Philippe E. Spiess ◽  
Sumanta K. Pal ◽  
David Josephson
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Metastatic Disease ◽  
Renal Cell ◽  
Locally Advanced ◽  
Disease Stage ◽  
Disease Characteristics ◽  
Multimodal Management

Both locally advanced and metastatic renal cell carcinoma (RCC) present a challenge in terms of their optimal management. This article reviews the literature and evaluates the role of surgery in the treatment of advanced RCC. Surgery is the optimal treatment for locally advanced RCC and minimal, resectable, metastatic disease. Patients with metastatic disease, and some forms of locally advanced disease, may also benefit from multimodal management with local surgical therapy and systemic treatment using either immunotherapy or targeted therapy. Regardless of the disease stage, patients with locally advanced or metastatic RCC represent heterogenous patient populations with different disease characteristics and risk factors. Individualization of care in the setting of a sound oncologic framework may optimize the risk/benefit ratio within individual patient cohorts.

scholarly journals MP66-10 CYTOREDUCTIVE NEPHRECTOMY AND VENOUS TUMOR THROMBECTOMY: THE ROLE OF QUANTIFIED METASTATIC DISEASE BURDEN IN A TARGETED THERAPY ERA

2018 ◽  
Vol 199 (4S) ◽  
Author(s):  
Deepak Pruthi ◽  
Hanzhang Wang ◽  
Michael Liss ◽  
Wasim Chowdhury ◽  
Ronald Rodriguez ◽  
...  
Keyword(s):  
Targeted Therapy ◽  
Metastatic Disease ◽  
Disease Burden ◽  
Cytoreductive Nephrectomy

Abstract A37: Role of autophagy inhibition in metastatic disease utilizing mouse models

2014 ◽  
Author(s):  
Rebecca Barnard ◽  
Ryan J. Hansen ◽  
Paola Maycotte ◽  
Andrew Thorburn ◽  
Daniel L. Gustafson
Keyword(s):  
Mouse Models ◽  
Metastatic Disease ◽  
Autophagy Inhibition

Principles of radiation oncology

2018 ◽  
Author(s):  
Jim Cassidy ◽  
Donald Bissett ◽  
Roy A. J. Spence OBE ◽  
Miranda Payne ◽  
Gareth Morris-Stiff
Keyword(s):  
Surgical Management ◽  
Metastatic Disease ◽  
Radiation Oncology

This chapter examines the principles of the surgical management of cancer including both curative and palliative resections, and the role of surgery in metastatic disease.

The role of surgery for locally recurrent and second recurrent rectal cancer with metastatic disease

2020 ◽  
Vol 35 ◽  
pp. 328-335
Author(s):  
Aya Tanaka ◽  
Kay Uehara ◽  
Toshisada Aiba ◽  
Atsushi Ogura ◽  
Toshiki Mukai ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Metastatic Disease ◽  
Recurrent Rectal Cancer ◽  
Locally Recurrent

The role of image-guided therapy in the management of colorectal cancer metastatic disease

2017 ◽  
Vol 75 ◽  
pp. 231-242 ◽  
Author(s):  
Thierry de Baere ◽  
Lambros Tselikas ◽  
Steven Yevich ◽  
Valérie Boige ◽  
Frederic Deschamps ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Metastatic Disease ◽  
Image Guided Therapy ◽  
Image Guided ◽  
Guided Therapy
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