scholarly journals MicroRNAs in Invasion and Metastasis in Lung Cancer

Author(s):  
Lili Jiang ◽  
Xueshan Qiu
2019 ◽  
Vol 10 (8) ◽  
pp. 1879-1889 ◽  
Author(s):  
Shuoke Li ◽  
Yangwei Ou ◽  
Shaobo Liu ◽  
Jiye Yin ◽  
Wei Zhuo ◽  
...  

2010 ◽  
Vol 70 (20) ◽  
pp. 7830-7840 ◽  
Author(s):  
Min-Wei Chen ◽  
Kuo-Tai Hua ◽  
Hsin-Jung Kao ◽  
Chia-Chun Chi ◽  
Lin-Hung Wei ◽  
...  

2018 ◽  
Vol 61 (1) ◽  
pp. T1-T10 ◽  
Author(s):  
Cheryl A Conover ◽  
Claus Oxvig

The zinc metalloproteinase, PAPP-A, enhances local insulin-like growth factor (IGF) action through cleavage of inhibitory IGF-binding proteins, thereby increasing IGF available for IGF receptor-mediated cell proliferation, migration and survival. In many tumors, enhanced IGF receptor signaling is associated with tumor growth, invasion and metastasis. We will first discuss PAPP-A structure and function, and post-translational inhibitors of PAPP-A expression or proteolytic activity. We will then review the evidence supporting an important role for PAPP-A in many cancers, including breast, ovarian and lung cancer, and Ewing sarcoma.


Oncotarget ◽  
2017 ◽  
Vol 8 (41) ◽  
pp. 70685-70694 ◽  
Author(s):  
Xiupeng Zhang ◽  
Yong Zhang ◽  
Yuan Miao ◽  
Haijing Zhou ◽  
Guiyang Jiang ◽  
...  

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