scholarly journals Corneal Endothelial Tissue Bioengineering Using Cultured Human Corneal Endothelial Precursor Cells

10.5772/55541 ◽  
2013 ◽  
Author(s):  
Tatsuya Mimura ◽  
Seiichi Yokoo ◽  
Satoru Yamagami
Keyword(s):  
Precursor Cells ◽  
Endothelial Tissue

Induction of Endothelial Tissue Factor by Endotoxin and Its Precursors

1993 ◽  
Vol 70 (04) ◽  
pp. 702-706 ◽  
Author(s):  
Charles F Moldow ◽  
Ronald R Bach ◽  
Katherine Staskus ◽  
Paul D Rick
Keyword(s):  
Tissue Factor ◽  
Lipid A ◽  
Umbilical Vein ◽  
Structural Determinants ◽  
Monophosphoryl Lipid A ◽  
Maximal Induction ◽  
Umbilical Vein Endothelial Cells ◽  
Acyloxyacyl Hydrolase ◽  
Endothelial Tissue ◽  
Specific Mrna

SummaryThe structural determinants of lipopolysaccharide required for the induction of tissue factor in human umbilical vein endothelial cells were studied. Intact lipid A was essential for the induction of tissue factor whereas the incomplete lipid A precursors lipid IVA and lipid X, as well as monophosphoryl lipid A and acyloxyacyl hydrolase-treated lipopolysaccharide, were unable to induce tissue factor and tissue factor specific mRNA. However, the lipid A precursor, lipid IVA, was able to inhibit LPS-mediated induction of tissue factor; structural determinants distal to lipid A were found to be required for maximal induction of tissue factor activity and tissue factor mRNA. The presence of serum in the assay was found to amplify but was not obligate for tissue factor induction by LPS.

The influence of T-lymphocyte precursor cells and thymus grafts on the cellular immunodeficiencies of the BB rat

Diabetes ◽  
1985 ◽  
Vol 34 (11) ◽  
pp. 1134-1138 ◽  
Author(s):  
J. W. Francfort ◽  
A. Naji ◽  
W. K. Silvers ◽  
C. F. Barker
Keyword(s):  
T Lymphocyte ◽  
Precursor Cells ◽  
Bb Rat
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