scholarly journals From Animal Models to Clinical Practicality: Lessons Learned from Current Translational Progress of Diabetic Peripheral Neuropathy

10.5772/55364 ◽  
2013 ◽  
Author(s):  
Chengyuan Li ◽  
Anne E. ◽  
John J.
Keyword(s):  
Peripheral Neuropathy ◽  
Animal Models ◽  
Diabetic Peripheral Neuropathy ◽  
Lessons Learned

scholarly journals Phenotyping animal models of diabetic peripheral neuropathy in rats: advantages and limitations

2018 ◽  
Vol 64 (3) ◽  
pp. 188-193
Author(s):  
Zera N. Abdulvapova ◽  
Ekaterina V. Artemova ◽  
Anna M. Gorbacheva ◽  
Gagik R. Galstyan ◽  
Alla Yu. Tokmakova ◽  
...  
Keyword(s):  
Peripheral Neuropathy ◽  
Animal Models ◽  
Diabetic Peripheral Neuropathy ◽  
Diabetic Polyneuropathy ◽  
Late Complications ◽  
Nerve Fibers ◽  
New Drugs ◽  
Diagnostic Features ◽  
Local Immunity ◽  
Fiber Damage

Diabetic polyneuropathy is one of the most common late complications of diabetes mellitus, as well as the main cause of ulcerative foot defects. The prevalence of neuropathy among people with diabetes varies from 28 to 65%, depending on the disease duration and diagnostic features. Initial signs of damage are detected as early as in prediabetes. To date, there is a fairly limited knowledge of the mechanisms of nerve fiber damage in diabetes. Also, it is unclear which type of nerve fibers is involved in damage first and how the nervous system regulates repair of tissues and local immunity. Animal models of diabetic peripheral neuropathy enable studying new aspects of the pathogenesis of this common diabetes complication and open prospects for the search and development of new drugs.

32-LB: Variations of Sole Images on Hard and Soft Floors Are Useful in the Prediction of Diabetic Peripheral Neuropathy and Diabetic Foot Diseases

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 32-LB
Author(s):  
SHENGPU CHOU ◽  
MIKIKO HARAGUCHI ◽  
HIROYA KOMORI ◽  
KOUHEI WATANABE ◽  
SATOKI TSUICHIHARA ◽  
...  
Keyword(s):  
Peripheral Neuropathy ◽  
Diabetic Foot ◽  
Diabetic Peripheral Neuropathy ◽  
Foot Diseases
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