scholarly journals Nanoparticles Toxicity and Their Routes of Exposures

10.5772/51230 ◽  
2012 ◽  
Author(s):  
Ahmet Aydn ◽  
Hande Sipahi ◽  
Mohammad Charehsaz
Keyword(s):  
Nanoparticles Toxicity

EXPERIMENTAL ASSESSMENT OF THE NANOPARTICLES TOXICITY OF NICKEL OXIDE IN TWO SIZES IN THE SUBCHRONIC EXPERIMENT

2018 ◽  
pp. 30-35
Author(s):  
M.P. Sutunkova ◽  
B.A. Katsnelson ◽  
L.I. Privalova ◽  
S.N. Solovjeva ◽  
V.B. Gurvich ◽  
...  
Keyword(s):  
Nickel Oxide ◽  
Nervous Activity ◽  
Equal Mass ◽  
The Body ◽  
Subchronic Toxicity ◽  
Physiological Mechanisms ◽  
Nickel Oxide Nanoparticles ◽  
The Relationship ◽  
The Brain ◽  
Nanoparticles Toxicity

We conducted a comparative assessment of the nickel oxide nanoparticles toxicity (NiO) of two sizes (11 and 25 nm) according to a number of indicators of the body state after repeated intraperitoneal injections of these particles suspensions. At equal mass doses, NiO nanoparticles have been found to cause various manifestations of systemic subchronic toxicity with a particularly pronounced effect on liver, kidney function, the body’s antioxidant system, lipid metabolism, white and red blood, redox metabolism, spleen damage, and some disorders of nervous activity allegedly related to the possibility of nickel penetration into the brain from the blood. The relationship between the diameter and toxicity of particles is ambiguous, which may be due to differences in toxicokinetics, which is controlled by both physiological mechanisms and direct penetration of nanoparticles through biological barriers and, finally, unequal solubility.

Quantum mechanics descriptors in a nano-QSAR model to predict metal oxide nanoparticles toxicity in human keratinous cells

2021 ◽  
Vol 23 (8) ◽  
Author(s):  
Eliecer Peláez Sifonte ◽  
Fidel Antonio Castro-Smirnov ◽  
Argenis Adrian Soutelo Jimenez ◽  
Héctor Raúl González Diez ◽  
Fernando Guzmán Martínez
Keyword(s):  
Quantum Mechanics ◽  
Metal Oxide ◽  
Metal Oxide Nanoparticles ◽  
Qsar Model ◽  
Oxide Nanoparticles ◽  
Nanoparticles Toxicity

A harmonized and standardized in vitro approach produces reliable results on silver nanoparticles toxicity in different cell lines

2021 ◽  
Author(s):  
Cristina Andreoli ◽  
Valentina Prota ◽  
Isabella De Angelis ◽  
Emiliano Facchini ◽  
Andrea Zijno ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Cell Lines ◽  
Nanoparticles Toxicity

Feedback mechanisms of periphytic biofilms to ZnO nanoparticles toxicity at different phosphorus levels

2021 ◽  
pp. 125834
Author(s):  
Shujie Cai ◽  
Haotian Wang ◽  
Jun Tang ◽  
Xiufeng Tang ◽  
Peng Guan ◽  
...  
Keyword(s):  
Zno Nanoparticles ◽  
Feedback Mechanisms ◽  
Nanoparticles Toxicity ◽  
Phosphorus Levels

Cabazitaxel-loaded poly(alkyl cyanoacrylate) nanoparticles: Toxicity and changes in the proteome of breast, colon and prostate cancer cells

2021 ◽  
pp. 1-20
Author(s):  
Anders Øverbye ◽  
Maria Lyngaas Torgersen ◽  
Tonje Sønstevold ◽  
Tore Geir Iversen ◽  
Ýrr Mørch ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Nanoparticles Toxicity

scholarly journals Redox proteomic insights into involvement of clathrin-mediated endocytosis in silver nanoparticles toxicity to Mytilus galloprovincialis

PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0205765 ◽  
Author(s):  
Younes Bouallegui ◽  
Ridha Ben Younes ◽  
Ridha Oueslati ◽  
David Sheehan
Keyword(s):  
Silver Nanoparticles ◽  
Mytilus Galloprovincialis ◽  
Nanoparticles Toxicity

scholarly journals Inorganic Nanoparticles: Toxic Effects, Mechanisms of Cytotoxicity and Phytochemical Interactions

2021 ◽  
Author(s):  
Rashid Bhatti ◽  
Hadia Shakeel ◽  
Kousar Malik ◽  
Muhammad Qasim ◽  
Mohsin Ahmad Khan ◽  
...  
Keyword(s):  
Metal Nanoparticles ◽  
Human Health ◽  
Reducing Agents ◽  
Inorganic Nanoparticles ◽  
Therapeutic Effects ◽  
Toxicological Effects ◽  
Prime Concern ◽  
Parkinson’S Diseases ◽  
Almost All ◽  
Nanoparticles Toxicity

During the last few decades, nanotechnology has gained many applications in almost all fields of life because of the unique properties of nanoparticles. Nanotechnology has specially marked its name in the field of medicine. However, nanoparticles toxicity is detrimental to human health and is a prime concern in applied medicine. They can cause insomnia, vertigo, madarosis, epistaxis, hypokalemia, lymphopenia, Alzheimer's and Parkinson's diseases, etc. There is a gap in knowledge regarding the study of the toxicological effects of nanoparticles. Mechanisms that are responsible for this toxicity are not fully understood yet. Phytochemicals have natural therapeutic effects of reducing metal nanoparticles' toxicity by acting as stabilizers and nontoxic reducing agents. However, the interaction between phytochemicals and nanoparticles is remained to be elucidated. This review will provide in-depth knowledge about the various types of inorganic nanoparticles and their associated toxicities, key parameters determining the toxic behaviour of nanoparticles, and the mechanisms behind their cytotoxicity. It also emphasizes the need for further research to understand the interaction between various phytochemicals and nanoparticles for therapeutic purposes.

Sign in / Sign up

Export Citation Format

Share Document