scholarly journals Glucose-6-Phosphate Dehydrogenase Deficiency and Malaria: A Method to Detect Primaquine-Induced Hemolysis in vitro

10.5772/48403 ◽  
2012 ◽  
Author(s):  
Adil M. ◽  
Malahat Bagirova ◽  
Serhat Elcicek ◽  
Rabia Cakir ◽  
Sezen Canim ◽  
...  
Keyword(s):  
Dehydrogenase Deficiency ◽  
Glucose 6 Phosphate Dehydrogenase

scholarly journals N-Acetylcysteine Reduces Methemoglobin in an In-vitro Model of Glucose-6-phosphate Dehydrogenase Deficiency

1998 ◽  
Vol 5 (3) ◽  
pp. 225-229 ◽  
Author(s):  
Robert O. Wright ◽  
Alan D. Woolf ◽  
Michael W. Shannon ◽  
Barbarajean Magnani
Keyword(s):  
In Vitro Model ◽  
Dehydrogenase Deficiency ◽  
Vitro Model ◽  
Glucose 6 Phosphate Dehydrogenase

scholarly journals Haemolytic potential of three chemotherapeutic agents and aspirin in glucose-6-phosphate dehydrogenase deficiency

1999 ◽  
Vol 5 (3) ◽  
pp. 457-464
Author(s):  
N. A. J. Ali ◽  
L. M. Al Naama ◽  
L. O. Khalid
Keyword(s):  
High Frequency ◽  
Dehydrogenase Deficiency ◽  
Local Population ◽  
Chemotherapeutic Agents ◽  
Red Cells ◽  
New Drugs ◽  
Local Variant ◽  
Glucose 6 Phosphate Dehydrogenase ◽  
Significant Concentration

The potential haemolytic effect of three chemotherapeutic drugs and aspirin was tested in vitro by gluthathione stability tests. Blood was collected from the local population of Basra, Iraq where previous studies had found a high frequency of glucose-6-phosphate dehydrogenase [G6PD] deficiency. Primaquine, chloramphenicol and sulfanilamide caused significant concentration-dependent reductions of glutathione levels in G6PD-deficient red cells when compared to normal red cells. Acetylsalicylic acid had no effect on glutathione level. The G6PD-deficient erythrocytes behaved as previously reported, probably due to similar patterns in the distribution of its variants. Studies on each local variant are warranted and new drugs should be tested for haemolytic potential prior to their introduction in areas where the deficiency is common

scholarly journals Sulfhemoglobinemia and Acute Hemolytic Anemia with Heinz Bodies Following Contact with a Fungicide— Zinc Ethylene Bisdithiocarbamate—in a Subject with Glucose-6-Phosphate Dehydrogenase Deficiency and Hypocatalasemia

Blood ◽  
1963 ◽  
Vol 21 (4) ◽  
pp. 484-494 ◽  
Author(s):  
JACK PINKHAS ◽  
MEIR DJALDETTI ◽  
HENRY JOSHUA ◽  
CHAIM RESNICK ◽  
ANDRÉ DE VRIES
Keyword(s):  
Red Blood Cells ◽  
Hemolytic Anemia ◽  
Blood Cells ◽  
Dehydrogenase Deficiency ◽  
Reduced Glutathione ◽  
Body Formation ◽  
Low Glucose ◽  
Glucose 6 Phosphate Dehydrogenase ◽  
Enzymatic Defect

Abstract Sulfhemoglobinemia associated with Heinz body formation and acute hemolytic anemia following contact with a fungicide, zinc ethylene bisdithiocarbamate, is described in a Persian Jew whose red blood cells had low glucose-6-phosphate dehydrogenase activity with low and unstable reduced glutathione and low catalase activity. The fungicide, similarly to acetylphenylhydrazine, was capable of decreasing in vitro the reduced glutathione of the patient’s red blood cells, as well as of those of other subjects with the same enzymatic defect. The sulfhemoglobinemia and the hemolytic anemia are considered to have been produced independently by the fungicide, the glucose-6-phosphate dehydrogenase deficiency having played a role only in the latter. The possibility that the hypocatalasemia was a factor in rendering the patient’s red blood cells sensitive to the hemolysis- and sulfhemoglobin-producing action of the fungicide is discussed. The importance of zinc ethylene bisdithiocarbamate as a sulfhemoglobin-producing and hemolytic agent is stressed, in view of the widespread use of this fungicide.

scholarly journals N-acetylcysteine Reduces Methemoglobin in an In Vitro Model of Glucose-6-phosphate Dehydrogenase Deficiency ♦ 364

1997 ◽  
Vol 41 ◽  
pp. 63-63
Author(s):  
Robert O. Wright ◽  
Barbarajean Magnani ◽  
Michael W. Shannon ◽  
Alan D. Woolf
Keyword(s):  
In Vitro Model ◽  
Dehydrogenase Deficiency ◽  
Vitro Model ◽  
Glucose 6 Phosphate Dehydrogenase

Glucose-6-Phosphate Dehydrogenase Deficiency in an Old Woman

2020 ◽  
Vol 6 (3) ◽  
Author(s):  
Briantais Antoine ◽  
Froidefond Margaux ◽  
Seguier Julie ◽  
Swiader Laure ◽  
Durand Jean Marc
Keyword(s):  
Dehydrogenase Deficiency ◽  
Glucose 6 Phosphate Dehydrogenase

Diversity in expression of glucose-6-phosphate dehydrogenase deficiency in females

1999 ◽  
Vol 55 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Yousef M Abdulrazzaq ◽  
Rosette Micallef ◽  
M Mansoor Qureshi ◽  
Adekunle Dawodu ◽  
Ibrahim Ahmed ◽  
...  
Keyword(s):  
Dehydrogenase Deficiency ◽  
Glucose 6 Phosphate Dehydrogenase
Sign in / Sign up

Export Citation Format

Share Document