scholarly journals Update on IgM Nephropathy

10.5772/39039 ◽  
2012 ◽  
Author(s):  
Javed I. ◽  
Muhammed Mubarak
Keyword(s):  
Igm Nephropathy

scholarly journals Immunoglobulin m (IGM) Nephropathy in children - report of two cases

2015 ◽  
Vol 23 (1) ◽  
pp. 131-133
Author(s):  
Shireen Afroz ◽  
Maliha Alam Simi ◽  
Shanjida Sharmin ◽  
Laila Yeasmin ◽  
LC Kundu
Keyword(s):  
Complete Remission ◽  
Immunoglobulin M ◽  
Oral Steroid ◽  
Membrane Thickness ◽  
Variable Degree ◽  
Basement Membrane Thickness ◽  
Igm Nephropathy ◽  
Steroid Dependence ◽  
First Case ◽  
Refractory Nephrotic Syndrome

Immunoglobulin M nephropathy (IgMN) is an idiopathic glomerulonephritis characterized by a variable degree of mesangialhypercellularity and diffuse IgM deposits.Patients usually presents with refractory nephrotic syndrome (NS) and hematuria. We present two patients with IgM nephropathy one with frequently relapsing NS with steroid dependence, treated with oral steroid and cyclophosphamide subsequently with tacrolimus. The patient showed complete remission but breakthrough relapses occurredduring the course of steroid treatment.The second case presented with persistentgross hematuria and nephroticrange proteinuria for 6 months. The patient showed complete remission of proteinuria and hematuria with oral steroid andremained on remission for9 months. Then again developed hematuria & proteinuria and subsequently showed response to oral steroid and cyclphosphamide . Renal histopathology & immunofluorescence study of first case revealed normal mesangial cellularity and basement membrane thickness with mesangial deposits of IgM. Second case showed global mesangial proliferation with increasing mesangial matrix with moderate mesangial deposits of IgM. DOI: http://dx.doi.org/10.3329/jdmc.v23i1.22709 J Dhaka Medical College, Vol. 23, No.1, April, 2014, Page 131-133

Clinical Follow-Up of 54 Patients with IgM-Nephropathy

1989 ◽  
Vol 9 (2) ◽  
pp. 124-128 ◽  
Author(s):  
Heikki Saha ◽  
Jukka Mustonen ◽  
Amos Pasternack ◽  
Heikki Helin
Keyword(s):  
Igm Nephropathy

scholarly journals Recurrence of IgM nephropathy in a renal allograft

2004 ◽  
Vol 19 (10) ◽  
pp. 2650-2652 ◽  
Author(s):  
A. H. J. Salmon ◽  
D. Kamel ◽  
P. W. Mathieson
Keyword(s):  
Renal Allograft ◽  
Igm Nephropathy

A Cause of Nephrotic Syndrome Rarely Seen in Adults: IgM Nephropathy

2014 ◽  
Vol 15 (3) ◽  
Author(s):  
Ayhan Haspulat ◽  
Ebru Gok Oguz ◽  
Tolga Yildirim ◽  
Zafer Ercan ◽  
Ozgur Merhametsiz ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Igm Nephropathy

Resolution of IgM Nephropathy After Rituximab Treatment

2009 ◽  
Vol 53 (6) ◽  
pp. 1059-1062 ◽  
Author(s):  
Michiel G.H. Betjes ◽  
Joke I. Roodnat
Keyword(s):  
Igm Nephropathy

scholarly journals Clinical Profile &Treatment Outcome in Children with IgM Nephropathy

2017 ◽  
Vol 16 (01) ◽  
pp. 14-19
Author(s):  
Pawan Mutalik ◽  
Subal Kumar Pradhan ◽  
Saroj Kumar Satapathy
Keyword(s):  
Treatment Outcome ◽  
Clinical Profile ◽  
Igm Nephropathy

scholarly journals IgM nephropathy in children: clinical, immunological, pathomorphological features

2019 ◽  
Vol 23 (5) ◽  
pp. 71-76
Author(s):  
I. A. Kazyra ◽  
A. V. Sukalo
Keyword(s):  
World Literature ◽  
Pediatric Nephrology ◽  
Morphological Characteristics ◽  
Igm Nephropathy ◽  
Steroid Dependence ◽  
Frequent Relapses ◽  
The World ◽  
Adults And Children ◽  
Few Data ◽  
Republican Center

BACKGROUND. Studies on the problem of IgM nephropathy in children in the world literature are few. Data on the disease in adults and children In Belarus have not previously been presented.THE AIM: to analyze the clinical, immunological, morphological characteristics, treatment regimen and prognostic factors of IgM nephropathy in children.PATIENTS AND METHODS. The study included 153 patients during the 6 years observed in the Republican Center for Pediatric Nephrology, among whom 21 were diagnosed with IgM nephropathy.RESULTS. Analysis of clinical, morphological features, the participation of markers of activation of T- and B-lymphocytes, pro-inflammatory and profibrotic molecules was performed.CONCLUSIONS. In most cases, IgM nephropathy is characterized by steroid dependence or resistance, or frequent relapses, which dictates the need to join cytostatic agent. In childhood is characterized by a benign course with no signs of progression.

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