scholarly journals Thermal Perturbations in Supersonic Transition

Author(s):  
Hong Yan
2015 ◽  
Vol 120 (2) ◽  
pp. 1210-1228 ◽  
Author(s):  
Khumo Leseane ◽  
Estella A. Atekwana ◽  
Kevin L. Mickus ◽  
Mohamed G. Abdelsalam ◽  
Elisha M. Shemang ◽  
...  

2012 ◽  
Vol 150 (3) ◽  
pp. 441-454 ◽  
Author(s):  
VINCENZO FESTA ◽  
ALFREDO CAGGIANELLI ◽  
ANTONIO LANGONE ◽  
GIACOMO PROSSER

AbstractTectonic and thermal perturbations, related to emplacement of granodiorite in the upper continental crust, have been investigated in the late-Hercynian basement exposed in southern Calabria (Italy). Here, the structural aureole is marked by the presence of a major rim fold adjacent to the intrusive contact for a length of at least 20 km. Geometrical analysis of the structural aureole and related foliations, lineations and crenulations reveals that the perturbed zone is at least 3000 m wide and characterized by an open synform trending nearly parallel to the intrusive contact. This pattern is compatible with a laccolith-like mode of magma emplacement, related to the accretion of the pluton that shouldered weak phyllitic and slaty wall rocks. The metamorphic aureole, about 1800 m wide, is characterized by biotite, cordierite and andalusite that appear sequentially in spotted schists and hornfelses approaching the intrusive contact. The peak assemblage equilibrated between 535 and 590°C at pressures between 175 and 200 MPa, confirmed by Al-in-hornblende barometry on granodiorite. Microstructural analysis allowed the inference of a time lag between the thermal and tectonic perturbations. With the aid of thermal modelling it was possible to quantify the time required to reach the peak temperature at a distance from the intrusive contact where cordierite spots and andalusite porphyroblasts clearly overprint crenulations. This estimate represents the time limit to accomplish deformation in the inner portion of the aureole and thus indicates a minimum strain rate of 4 × 10−14 s−1 within the country rocks during granodiorite intrusion.


2019 ◽  
Vol 20 (22) ◽  
pp. 5702 ◽  
Author(s):  
Rebecca C. Feiner ◽  
Julian Teschner ◽  
Kathrin E. Teschner ◽  
Marco T. Radukic ◽  
Tobias Baumann ◽  
...  

Recombinant adeno-associated viruses (rAAV) provide outstanding options for customization and superior capabilities for gene therapy. To access their full potential, facile genetic manipulation is pivotal, including capsid loop modifications. Therefore, we assessed capsid tolerance to modifications of the structural VP proteins in terms of stability and plasticity. Flexible glycine-serine linkers of increasing sizes were, at the genetic level, introduced into the 587 loop region of the VP proteins of serotype 2, the best studied AAV representative. Analyses of biological function and thermal stability with respect to genome release of viral particles revealed structural plasticity. In addition, insertion of the 29 kDa enzyme β-lactamase into the loop region was tested with a complete or a mosaic modification setting. For the mosaic approach, investigation of VP2 trans expression revealed that a Kozak sequence was required to prevent leaky scanning. Surprisingly, even the full capsid modification with β-lactamase allowed for the assembly of capsids with a concomitant increase in size. Enzyme activity assays revealed lactamase functionality for both rAAV variants, which demonstrates the structural robustness of this platform technology.


2020 ◽  
Vol 124 ◽  
pp. 103636
Author(s):  
Gong-Da Lu ◽  
Xing-Guo Yang ◽  
Shun-Chao Qi ◽  
Xi-Long Li ◽  
Pei-Pei Ding ◽  
...  

2008 ◽  
Vol 47 (2) ◽  
pp. 397-410 ◽  
Author(s):  
M. Baldi ◽  
G. A. Dalu ◽  
R. A. Pielke

Abstract It is shown that landscape variability decreases the temperature in the surface layer when, through mesoscale flow, cool air intrudes over warm patches, lifting warm air and weakening the static stability of the upper part of the planetary boundary layer. This mechanism generates regions of upward vertical motion and a sizable amount of available potential energy and can make the environment of the lower troposphere more favorable to cloud formation. This process is enhanced by light ambient wind through the generation of trapped propagating waves, which penetrate into the midtropospheric levels, transporting upward the thermal perturbations and weakening the static stability around the top of the boundary layer. At moderate ambient wind speeds, the presence of surface roughness changes strengthens the wave activity, further favoring the vertical transport of the thermal perturbations. When the intensity of the ambient wind is larger than 5 m s−1, the vertical velocities induced by the surface roughness changes prevail over those induced by the diabatic flux changes. The analysis is performed using a linear theory in which the mesoscale dynamics are forced by the diurnal diabatic sensible heat flux and by the surface stress. Results are shown as a function of ambient flow intensity and of the wavelength of a sinusoidal landscape variability.


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