scholarly journals Diagnosis of Chlamydia trachomatis Infection

Chlamydia ◽  
10.5772/38804 ◽  
2012 ◽  
Author(s):  
Adele Visser ◽  
Anwar Hoose
Keyword(s):  
Chlamydia Trachomatis ◽  
Chlamydia Trachomatis Infection

scholarly journals P3.026 Low Prevalence of Chlamydia Trachomatis Infection: Fact or Missed Diagnosis?

2013 ◽  
Vol 89 (Suppl 1) ◽  
pp. A156.1-A156
Author(s):  
T Bharara ◽  
D Rawat ◽  
P Bhalla ◽  
V K Garg ◽  
K Sardana ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Chlamydia Trachomatis Infection ◽  
Missed Diagnosis ◽  
Low Prevalence

scholarly journals Differential Regulation of Inflammatory Cytokine Secretion by Human Dendritic Cells upon Chlamydia trachomatis Infection

2004 ◽  
Vol 72 (12) ◽  
pp. 7231-7239 ◽  
Author(s):  
Ana Gervassi ◽  
Mark R. Alderson ◽  
Robert Suchland ◽  
Jean François Maisonneuve ◽  
Kenneth H. Grabstein ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Chlamydia Trachomatis ◽  
Wide Spectrum ◽  
Cytokine Secretion ◽  
Host Cells ◽  
Microbial Pathogens ◽  
Potential Contribution ◽  
Necrosis Factor Alpha ◽  
Chlamydia Trachomatis Infection ◽  
Tnf Α

ABSTRACT Chlamydia trachomatis is an obligate intracellular gram-negative bacterium responsible for a wide spectrum of diseases in humans. Both genital and ocular C. trachomatis infections are associated with tissue inflammation and pathology. Dendritic cells (DC) play an important role in both innate and adaptive immune responses to microbial pathogens and are a source of inflammatory cytokines. To determine the potential contribution of DC to the inflammatory process, human DC were infected with C. trachomatis serovar E or L2. Both C. trachomatis serovars were found to infect and replicate in DC. Upon infection, DC up-regulated the expression of costimulatory (B7-1) and cell adhesion (ICAM-1) molecules. Furthermore, chlamydial infection induced the secretion of interleukin-1β (IL-1β), IL-6, IL-8, IL-12p70, IL-18, and tumor necrosis factor alpha (TNF-α). The mechanisms involved in Chlamydia-induced IL-1β and IL-18 secretion differed from those of the other cytokines. Chlamydia-induced IL-1β and IL-18 secretion required infection with viable bacteria and was associated with the Chlamydia-induced activation of caspase-1 in infected host cells. In contrast, TNF-α and IL-6 secretion did not require that the Chlamydia be viable, suggesting that there are at least two mechanisms involved in the Chlamydia-induced cytokine secretion in DC. Interestingly, an antibody to Toll-like receptor 4 inhibited Chlamydia-induced IL-1β, IL-6, and TNF-α secretion. The data herein demonstrate that DC can be infected by human C. trachomatis serovars and that chlamydial components regulate the secretion of various cytokines in DC. Collectively, these data suggest that DC play a role in the inflammatory processes caused by chlamydial infections.

Scrotal mass with fever and generalized lymphadenopathy in a young man secondary to Chlamydia trachomatis infection

2005 ◽  
Vol 51 (3) ◽  
pp. e107-e108 ◽  
Author(s):  
N.E. Jenkins ◽  
L. Radcliffe ◽  
Mike Beadsworth ◽  
H. Mallinson ◽  
Fred Nye ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Scrotal Mass ◽  
Chlamydia Trachomatis Infection ◽  
Generalized Lymphadenopathy

scholarly journals Comparison of the ligase chain reaction with cell culture for the diagnosis of Chlamydia trachomatis infection in women.

1996 ◽  
Vol 49 (2) ◽  
pp. 116-119 ◽  
Author(s):  
G L Ridgway ◽  
G Mumtaz ◽  
A J Robinson ◽  
M Franchini ◽  
C Carder ◽  
...  
Keyword(s):  
Cell Culture ◽  
Chlamydia Trachomatis ◽  
Chain Reaction ◽  
Ligase Chain Reaction ◽  
Chlamydia Trachomatis Infection

Decreased occurrence of endometriosis in women with Chlamydia trachomatis infection

2021 ◽  
Author(s):  
Khaleque N. Khan ◽  
Akira Fujishita ◽  
Michio Kitajima ◽  
Tadayuki Ishimaru ◽  
Kanae Ogawa ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Chlamydia Trachomatis Infection
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