scholarly journals Enteral Nutrition as a Life-Saving Treatment in Patients with Severe Anorexia Nervosa

Author(s):  
Maria Gabriella
Author(s):  
Jonathan Pugh

This chapter brings the rationalist account of decision-making capacity to bear on three case studies. The first concerns a patient who ‘unwisely’ refuses treatment for a condition that can be treated straightforwardly, but which will otherwise be fatal. The second concerns a Jehovah’s Witness who refuses a life-saving blood transfusion. The third concerns an individual suffering from anorexia nervosa, who recognizes that she is dangerously underweight, but who nonetheless refuses to consume food. The author argues that a rationalist approach can accommodate the thought that an individual’s decision-making capacity is not precluded by their making an ‘unwise’ decision. It can also accommodate both the thought that Jehovah’s Witnesses can have decision-making capacity to refuse blood transfusions, and that some sufferers of anorexia nervosa may lack decision-making capacity. The author argues that his account is better equipped to investigate the nuances of these hard cases than the standard account.


2006 ◽  
Vol 30 (3) ◽  
pp. 231-239 ◽  
Author(s):  
Agostino Paccagnella ◽  
Alessandra Mauri ◽  
Carla Baruffi ◽  
Rita Berto ◽  
Raffaella Zago ◽  
...  

2008 ◽  
Vol 26 (3) ◽  
pp. 129-136 ◽  
Author(s):  
M. Nardi ◽  
L. CAREGARO ◽  
A. FAVARO ◽  
E. Zola ◽  
G. BOFFO ◽  
...  

2021 ◽  
Vol 46 ◽  
pp. S598
Author(s):  
M. Dicembre ◽  
D. Sanchez ◽  
M. Duquesnoy ◽  
C. Finck ◽  
N. Kayser ◽  
...  

Gut ◽  
1997 ◽  
Vol 41 (2) ◽  
pp. 203-208 ◽  
Author(s):  
M Azcue ◽  
M Rashid ◽  
A Griffiths ◽  
P B Pencharz

Background—Malnutrition and growth retardation are common complications of Crohn’s disease in children. The contribution of resting energy expenditure (REE) to malnutrition is unclear.Aims—To characterise the REE and body composition in children with Crohn’s disease and compare them with normal controls and patients with anorexia nervosa; to compare the effects of prednisolone and enteral nutrition on energy expenditure and body composition.Subjects—Twenty four children with Crohn’s disease, 19 malnourished females with anorexia nervosa, and 22 healthy control subjects were studied.Methods—In children with Crohn’s disease measurements were done when the disease was acute and repeated at one and three months after treatment with either prednisolone or enteral nutrition. Resting energy expenditure was measured by indirect calorimetry and body composition by anthropometry, bioelectrical impedance analysis, total body potassium, H218O, and bromide space studies.Results—Body weight and ideal body weight were significantly lower in patients with Crohn’s disease than in healthy controls. Lean tissue was depleted and there was an increase in extracellular water. Per unit of lean body mass, there was no difference between REE in patients with Crohn’s disease and controls, whereas patients with anorexia nervosa had significantly reduced REE. With enteral nutrition all body compartments and REE increased significantly (p<0.001). In a subgroup of age-matched men there was a significant increase in height after three months of enteral nutrition compared with prednisolone (p<0.01). Those treated with steroids did not show a significant change in height but did show an increase in all body compartments. However, intracellular water as well as lean body mass accretion were significantly higher in the enteral nutrition group than in the prednisolone group.Conclusions—Despite being malnourished, children with Crohn’s disease fail to adapt their REE per unit of lean body mass. This might be a factor contributing to their malnutrition. Lean tissue accretion is higher in patients treated with enteral nutrition than in those treated with prednisolone.


Neurosurgery ◽  
2017 ◽  
Vol 83 (1) ◽  
pp. 86-92 ◽  
Author(s):  
Wei Liu ◽  
Dianyou Li ◽  
Fafa Sun ◽  
Xiaoxiao Zhang ◽  
Tao Wang ◽  
...  

Abstract BACKGROUND Anorexia nervosa (AN) is one of the most challenging psychiatric disorders to treat. The poor clinical outcomes warrant novel treatments for AN, especially in severe and persistent cases. OBJECTIVE To explore the feasibility of magnetic resonance imaging-guided bilateral anterior capsulotomy in the treatment of refractory AN. METHODS Seventy-four patients diagnosed with refractory AN who underwent capsulotomy completed this 3-yr follow-up study. Outcomes included body mass index (BMI) and results from a series of psychiatric scales (for obsessive, depressive, and anxious symptoms) that were implemented at baseline (presurgery), and 1 mo, 1 yr, and 3 yr after surgery. RESULTS Compared to presurgical levels, BMI increased significantly at 1-yr and 3-yr follow-ups. Compared to presurgery scores, psychiatric scale scores were significantly improved at 1-mo postsurgery, and continued to remain low at the 1-yr and 3-yr follow-ups. In addition, Mini-Mental State Examination (MMSE) scores were in the normal range during the long-term follow-up. The most common short-term side effects included urinary incontinence (n = 7), sleep disorders (n = 8), and fatigue (n = 6). Long-term complications included disinhibition (n = 6), memory loss (n = 3), and lethargy (n = 4). No patient in this study experienced death or disability. CONCLUSION Capsulotomy enabled patients with refractory AN to normalize their weight, especially those in life-threatening conditions. While it appears to be an acceptable life-saving treatment, it is indicated only when fulfilling strict criteria given its complications and irreversibility.


1990 ◽  
Vol 14 (4) ◽  
pp. 404-407 ◽  
Author(s):  
Giovanni Bufano ◽  
Carlotta Bellini ◽  
Gianfranco Cervellin ◽  
Carlo Coscelli

Nutrients ◽  
2012 ◽  
Vol 4 (9) ◽  
pp. 1293-1303 ◽  
Author(s):  
Maria Gabriella Gentile

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