scholarly journals Additive Manufacturing Solutions for Improved Medical Implants

Biomedicine ◽  
10.5772/38349 ◽  
2012 ◽  
Author(s):  
Vojislav Petrovic ◽  
Juan Vicente ◽  
Jose Ramn ◽  
Luis Portols
Keyword(s):  
Additive Manufacturing ◽  
Medical Implants

scholarly journals A Review on Development of Bio-Inspired Implants Using 3D Printing

Biomimetics ◽  
2021 ◽  
Vol 6 (4) ◽  
pp. 65
Author(s):  
Ansheed A. Raheem ◽  
Pearlin Hameed ◽  
Ruban Whenish ◽  
Renold S. Elsen ◽  
Aswin G ◽  
...  
Keyword(s):  
Additive Manufacturing ◽  
3D Printing ◽  
Layer By Layer ◽  
Medical Implants ◽  
3D Print ◽  
Metal Implants ◽  
Natural Tissue ◽  
And Control ◽  
Natural Architecture ◽  
Fine Tune

Biomimetics is an emerging field of science that adapts the working principles from nature to fine-tune the engineering design aspects to mimic biological structure and functions. The application mainly focuses on the development of medical implants for hard and soft tissue replacements. Additive manufacturing or 3D printing is an established processing norm with a superior resolution and control over process parameters than conventional methods and has allowed the incessant amalgamation of biomimetics into material manufacturing, thereby improving the adaptation of biomaterials and implants into the human body. The conventional manufacturing practices had design restrictions that prevented mimicking the natural architecture of human tissues into material manufacturing. However, with additive manufacturing, the material construction happens layer-by-layer over multiple axes simultaneously, thus enabling finer control over material placement, thereby overcoming the design challenge that prevented developing complex human architectures. This review substantiates the dexterity of additive manufacturing in utilizing biomimetics to 3D print ceramic, polymer, and metal implants with excellent resemblance to natural tissue. It also cites some clinical references of experimental and commercial approaches employing biomimetic 3D printing of implants.

ADDITIVE MANUFACTURING PARAMETERS OPTIMIZATION OF Ti6AL4V ELI FOR MEDICAL IMPLANTS

2022 ◽  
Author(s):  
VIJAY KUMAR MEENA ◽  
PARVEEN KALRA ◽  
RAVINDRA KUMAR SINHA
Keyword(s):  
Surface Roughness ◽  
Additive Manufacturing ◽  
Weight Ratio ◽  
High Strength ◽  
Surface Characteristics ◽  
Parameters Optimization ◽  
Medical Implants ◽  
Scan Speed ◽  
Grey Relational ◽  
Manufacturing Parameters

Additive manufacturing (AM) of titanium (Ti) alloys has always fascinated researchers owing to its high strength to weight ratio, biocompatibility, and anticorrosive properties, making Ti alloy an ideal candidate for medical applications. The aim of this paper is to optimize the AM parameters, such as Laser Power (LP), Laser Scan Speed (LSS), and Hatch Space (HS), using Analysis of Variance (ANOVA) and Grey Relational analysis (GRA) for mechanical and surface characteristics like hardness, surface roughness, and contact angle, of Ti6Al4V ELI considering medical implant applications. The input parameters are optimized to have optimum hardness, surface roughness and hydrophilicity required for medical implants.

Structural optimisation for medical implants through additive manufacturing

2020 ◽  
Vol 5 (2) ◽  
pp. 95-110
Author(s):  
Abdulsalam Abdulaziz Al-Tamimi ◽  
Henrique Almeida ◽  
Paulo Bartolo
Keyword(s):  
Additive Manufacturing ◽  
Medical Implants ◽  
Structural Optimisation

scholarly journals Qualification of Customised Medical Implants Produced by Ti6Al4V(ELI) Additive Manufacturing

2020 ◽  
Vol 321 ◽  
pp. 03012
Author(s):  
W B du Preez ◽  
G J Booysen
Keyword(s):  
Additive Manufacturing ◽  
Quality Management ◽  
Management System ◽  
Quality Management System ◽  
Titanium Implants ◽  
International Standards ◽  
Patient Specific ◽  
Medical Implants ◽  
Design Development ◽  
Custom Made

Although many cases of medical implants produced through additive manufacturing (AM) in Ti6Al4V have been reported in literature, most of these processes had not been qualified. To enable certification and commercialisation of medical implants and devices an ISO 13485:2016 quality management system was successfully implemented in the Centre for Rapid Prototyping and Manufacturing (CRPM) at the Central University of Technology, Free State in South Africa. This certification covers qualification of both design, development and production of patient specific custom made titanium implants, as well as preoperative models, jigs and cutting guides in nylon by means of AM and supports commercialisation. With this quality management system as framework for ensuring the reliability and repeatability of the AM performed at the CRPM, the generation of data to validate the individual processes in the AM process chain was pursued. Sufficient research data has been produced and published to prove that medical implants produced through AM can fully comply with the international standards for material, physical, chemical and mechanical properties. In this paper the research performed towards the qualification of AM of Ti6Al4V medical implants is discussed. Examples are given of internationally leading work on utilising these implants in maxillofacial and orthopaedic surgeries.

Tribological Review of Medical Implants Manufactured by Additive Manufacturing

2021 ◽  
pp. 379-395
Author(s):  
Mohd Javaid ◽  
Suresh Babu ◽  
Shanay Rab ◽  
Raju Vaishya ◽  
Abid Haleem
Keyword(s):  
Additive Manufacturing ◽  
Medical Implants

Establishing a Quality Management System for Production of Certified Customised Titanium Medical Implants through Additive Manufacturing

MRS Advances ◽  
2020 ◽  
Vol 5 (26) ◽  
pp. 1387-1396
Author(s):  
W B du Preez ◽  
D J de Beer ◽  
G J Booysen
Keyword(s):  
Additive Manufacturing ◽  
Quality Management ◽  
Management System ◽  
Quality Management System ◽  
Titanium Implants ◽  
Patient Specific ◽  
Medical Implants ◽  
Validation Data ◽  
Custom Made

ABSTRACTVarious cases of medical implants produced through additive manufacturing (AM) in Ti6Al4V have been reported in literature. Not all manufacturing processes used, were qualified. In striving to deliver certified AM medical implants and devices, an ISO 13485:2016 quality management system was implemented in the Centre for Rapid Prototyping and Manufacturing (CRPM) of the Central University of Technology, Free State (CUT) in Bloemfontein, South Africa. This certification is valid for design, development and production of patient-specific custom-made titanium implants, preoperative models, jigs and cutting-guides in nylon through AM, and contract-production of these products. For maintaining this quality management system, the generation of data to validate the individual processes in the AM process-chain is crucial to prove the DMLS product-quality of CRPM’s products. During the past five years, directed research data was produced and published to prove that medical implants produced through DMLS can fully comply with the accepted international standards for material, physical, chemical and mechanical properties of such parts. The paper discusses the quality management system’s establishment; materials research projects executed to generate validation data are mentioned; and examples of customised titanium implants for restoring the quality of life of patients are shown.

scholarly journals A New Methodology for Designing a Skull Implant

2021 ◽  
pp. 21-30
Author(s):  
Nassim Markiz ◽  
Eszter Horváth ◽  
Péter Ficzere
Keyword(s):  
Computed Tomography ◽  
Additive Manufacturing ◽  
Bone Defect ◽  
Development Time ◽  
Rapid Development ◽  
Medical Implants ◽  
Current State ◽  
Cranial Implant ◽  
Industrial Software ◽  
Replacement Part

Cranioplasty is a surgery used to repair a bone defect in the skull caused by an injury. It involves lifting the scalp and restoring the contour of the skull with an implant usually manufactured by additive manufacturing. The cranial implant is a sensitive topic; thus, it must be manufactured to the highest standards. Medical implants are growing significantly due to industrial digitalization and the rapid development of industrial software. With the help of computed Tomography (CT) equipment, a spatial, rotating model of the patient's current state can be obtained quickly, even in minutes where the replacement part of the deficiency can be perfectly designed. Although this requires considerable routine, computational capacity, and time, but taking advantage of the latest software presented in our manuscript, the development time of the implant can be up to 50 times shorter with significant improvements in suitability and adaptability. Subsequently, we can produce more accurate implants with more accessible and faster manufacturing with our developed method. The development steps and methods of designing an implant are described in our article.

scholarly journals A Comprehensive Review on Bio-Nanomaterials for Medical Implants and Feasibility Studies on Fabrication of Such Implants by Additive Manufacturing Technique

Materials ◽  
2019 ◽  
Vol 13 (1) ◽  
pp. 92 ◽  
Author(s):  
Rajkumar Velu ◽  
Theo Calais ◽  
Arunkumar Jayakumar ◽  
Felix Raspall
Keyword(s):  
Additive Manufacturing ◽  
Medical Device ◽  
Feasibility Studies ◽  
Medical Implants ◽  
Implantable Medical Device ◽  
Comprehensive Review ◽  
Manufacturing Technique ◽  
Holistic Assessment ◽  
Processing Techniques ◽  
Bio Engineering

Nanomaterials have allowed significant breakthroughs in bio-engineering and medical fields. In the present paper a holistic assessment on diverse biocompatible nanocomposites are studied. Their compatibility with advanced fabrication methods such as additive manufacturing for the design of functional medical implants is also critically reviewed. The significance of nanocomposites and processing techniques is also envisaged comprehensively in regard with the needs and futures of implantable medical device industries.

A Comparative Study of Surface Cleaning Treatments for 3D Printed Medical Implants

2017 ◽  
Author(s):  
Lucy Guo ◽  
Zhiqiang Xie ◽  
Hong Yao ◽  
Ying Wang
Keyword(s):  
Additive Manufacturing ◽  
Comparative Study ◽  
Surface Cleaning ◽  
Valuable Insight ◽  
Medical Implants ◽  
Post Process ◽  
Metal Printing ◽  
Weak Points ◽  
3D Metal Printing ◽  
3D Printed

In the field of Additive Manufacturing (AM), one of the major applications of laser-based 3D metal printing is the creation of custom implants for medical purposes. However, a significant challenge in the manufacturing of implants using Selective Laser Melting (SLM) is the formation of partially melted particles on the surface of medical implants. These particles result in a multitude of issues including plurality of structurally weak points on the designed implants, obstruction of important design features, and possibility of dislodgement over the service life span, thereby posing a threat to the recipient. To address the above challenges, it is imperative to develop a simple but effective surface cleaning method to remove partially melted particles from the surface without damage to the designed medical implants. In this work, a comparative study was conducted to investigate the effect of both chemical and electro-plasma based cleaning processes on the removal of partially melted particles from the surfaces of 3D printed Ti-6Al-4V medical screw implants. These techniques include chemically polishing implants with HF-HNO3 acid solutions and using an electro-plasma based cleaning process. With the field of additive manufacturing rapidly expanding, this work offers valuable insight on proper post-process treatment of 3D printed parts for future medical purposes in biomedical fields.

scholarly journals Advantages of Additive Manufacturing for Biomedical Applications of Polyhydroxyalkanoates

2021 ◽  
Vol 8 (2) ◽  
pp. 29
Author(s):  
Alberto Giubilini ◽  
Federica Bondioli ◽  
Massimo Messori ◽  
Gustav Nyström ◽  
Gilberto Siqueira
Keyword(s):  
Additive Manufacturing ◽  
Biomedical Applications ◽  
Growth Conditions ◽  
Special Focus ◽  
Medical Implants ◽  
Production Techniques ◽  
Rapid Prototyping And Manufacturing ◽  
Commercial Applications ◽  
Tunable Mechanical Properties ◽  
Near Future

In recent years, biopolymers have been attracting the attention of researchers and specialists from different fields, including biotechnology, material science, engineering, and medicine. The reason is the possibility of combining sustainability with scientific and technological progress. This is an extremely broad research topic, and a distinction has to be made among different classes and types of biopolymers. Polyhydroxyalkanoate (PHA) is a particular family of polyesters, synthetized by microorganisms under unbalanced growth conditions, making them both bio-based and biodegradable polymers with a thermoplastic behavior. Recently, PHAs were used more intensively in biomedical applications because of their tunable mechanical properties, cytocompatibility, adhesion for cells, and controllable biodegradability. Similarly, the 3D-printing technologies show increasing potential in this particular field of application, due to their advantages in tailor-made design, rapid prototyping, and manufacturing of complex structures. In this review, first, the synthesis and the production of PHAs are described, and different production techniques of medical implants are compared. Then, an overview is given on the most recent and relevant medical applications of PHA for drug delivery, vessel stenting, and tissue engineering. A special focus is reserved for the innovations brought by the introduction of additive manufacturing in this field, as compared to the traditional techniques. All of these advances are expected to have important scientific and commercial applications in the near future.

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