scholarly journals Morphology and Functional Changes of Intestine, Trophology Status and Systemic Inflammation in Patients with Chronic Heart Failure

10.5772/38283 ◽  
2012 ◽  
Author(s):  
G.P. Arutyunov ◽  
N.A. Bylov
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Systemic Inflammation ◽  
Functional Changes

scholarly journals CHRONIC HEART FAILURE CAUSES OSTEOPATHY OR IS OSTEOPATHY A FACTOR IN DEVELOPMENT OF CHRONIC HEART FAILURE?

2018 ◽  
Vol 11 (1) ◽  
pp. 111
Author(s):  
Mariya Marushchak ◽  
Inna Krynytska ◽  
Anna Mikolenko ◽  
Yurii Andreychyn ◽  
Yaroslav Bodnar
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Bone Mineralization ◽  
Stage I ◽  
Proximal Segment ◽  
Equal Proportion ◽  
Lumbar Region ◽  
Mineral Density ◽  
Functional Changes ◽  
The Right

Objective: As their proportion rises in the aging population, cardiovascular disease and osteoporosis increasingly become significant health problems of the developed world, leading to reduced lifespan and substantial financial burdens, not the least because of complications and comorbidities associated with each disorder. This study investigates bone mineralization in patients with coronary heart disease (CHD) complicated by Stage I chronic heart failure (CHF).Methods: The study group consisted of 41 patients of both sexes with CHF Stage I against the background of CHD that with no severe comorbidities that could have potentially caused changes in bone tissue. Bone mineral density was measured using dual-energy X-ray densitometry of lumbar region of spine and proximal right femur.Results: Structural and functional changes in the bone of the lumbar spine were found in 75.9% of the patients with Stage I CHF caused by CHD. Osteopenia was diagnosed in 64.4% of the patients, while osteosclerotic bone changes were less frequent and found in 11.5% of the patients. 75.8% of the patients had structural and functional changes in the proximal segment of the right femur bone. In men with Stage I CHF against the background of CHD osteopenia was more often diagnosed in the proximal segment of the right femur, while in women it was found in almost equal proportion in the spine and hip.Conclusions: In both sexes with I Stage CHF against the background of CHD were diagnosed changes in bone mineralization, with osteopenia being the prevailing diagnosis. 

Possible cause of systemic inflammation in patients with chronic heart failure of different classes

2008 ◽  
Vol 17 ◽  
pp. S9
Author(s):  
Nadezda Bylova ◽  
Gregory Arutyunov ◽  
Ludmila Kafarskaya ◽  
Nikolay Savelov ◽  
Yurii Pokrovsky ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Systemic Inflammation ◽  
Possible Cause

Systemic inflammation and cell activation reflects morbidity in chronic heart failure

Cytokine ◽  
2011 ◽  
Vol 56 (3) ◽  
pp. 593-599 ◽  
Author(s):  
Dani-Louise Dixon ◽  
Kim M. Griggs ◽  
Andrew D. Bersten ◽  
Carmine G. De Pasquale
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Systemic Inflammation ◽  
Cell Activation

scholarly journals Metabolic syndrome and chronic heart failure: a modern aspect of the problem

2022 ◽  
Vol 21 (1) ◽  
pp. 105-113
Author(s):  
Tatiana Fedorova ◽  
Natalya Semenenko ◽  
Serafima Tazina ◽  
Alexander Mamonov ◽  
Tatiana Sotnikova
Keyword(s):  
Heart Failure ◽  
Metabolic Syndrome ◽  
Chronic Heart Failure ◽  
Clinical Course ◽  
Rapid Development ◽  
Medical Science ◽  
Left Ventricular ◽  
Modern Aspect ◽  
Functional Changes

Objective: The increase of morbidity results from both an increase of life expectancy of the population, and influence of various risk factors contributing to development and increase of chronic heart failure (CHF). The combination of several atherogenic mechanisms (abdominal obesity (AO), insulin resistance (IR), arterial hypertension (AH), hyperglycemia, dyslipidemia), combined as “metabolic syndrome” (MS), causes a more rapid development of CHF. Materials and methods: The research finding of 74 patients with class II-III of CHF, including 37 patients (50%) with MS, are presented. The age structure of the pathology, severity of clinical course, data of laboratory and instrumental examination in various groups of patients were evaluated. A special program included an echocardiographic test with an assessment of various myocardial parameters. Results and Discussion: Research materials find out a number of characteristics of CHF clinical course (its earlier development and severe course) in patients with MS. Echocardiographic tests reveal an increase of heart chambers sizes, thickness of left and right ventricle, pulmonary hypertension. Myocardium morpho-functional changes are more significant in patients with CHF and MS than in those without MS. An increase in leptin levels, a marker of obesity, fibrosis and inflammation, has been found. Leptin, C-reactive peptide (CRP) and high-sensitive troponin in patients with MS significantly exceeded those in patientswithout MS. Correlations of leptin levels, adiponectin, CRP and left ventricular mass, thickness of epicardial fat (TEF), ejection fraction were established. Conclusion: Materials of the research indicate the important role of inflammatory and dysmetabolic processes in development and progression of CHF in patients with MS. Bangladesh Journal of Medical Science Vol. 21(1) 2022 Page : 105-113

Cardiac and vascular ageing

2017 ◽  
pp. 729-736
Author(s):  
Hidetaka Ota ◽  
Masahiro Akishita
Keyword(s):  
Heart Failure ◽  
Cardiovascular Disease ◽  
Cardiovascular Diseases ◽  
Chronic Heart Failure ◽  
Left Ventricular Hypertrophy ◽  
Blood Vessels ◽  
Left Ventricular ◽  
Functional Changes ◽  
Healthy Humans ◽  
Vascular Ageing

There is a continuum of expression of cardiac structural and functional alterations that occurs with ageing in healthy humans, and these age-associated cardiac changes seem to be relevant to the increase in left ventricular hypertrophy, chronic heart failure, and arrhythmia that are commonly observed with increasing age. This chapter describes the structural and functional changes in the ageing process of the heart and blood vessels, and provides an overview of representative cardiovascular disease caused by ageing including hypertension, atherosclerosis, and heart failure. In addition, an outline of interventions that have be utilized to prevent and treat ageing related cardiovascular diseases is provided.

scholarly journals Results of the Ultrasound Study of Intracardial Hemodynamics in Patients with Ischemic Heart Disease in Combination with Arterial Hypertension and Complicated by Chronic Heart Failure 2A and 2B

2017 ◽  
Vol 24 (3) ◽  
Author(s):  
Nina Matsegora ◽  
Nataliia Mitasova
Keyword(s):  
Heart Failure ◽  
Pulmonary Hypertension ◽  
Heart Disease ◽  
Chronic Heart Failure ◽  
Ischemic Heart Disease ◽  
Arterial Hypertension ◽  
Functional Class ◽  
Ischemic Heart ◽  
Functional Changes ◽  
Ultrasound Study

Objective. To conduct a comprehensive study of patients with ischemic heart disease (IHD) in combination with arterial hypertension (AH) complicated by chronic heart failure (HF) 2A and 2B, by studying parameters of intracardiac hemodynamics considering the pressure in the pulmonary artery.Research results. We examined 120 patients with coronary heart disease in combination with hypertension aged 44 to 90 years old (mean age 72.29 ± 1.66), the majority were men (86.7%). All patients were divided into two groups according to the degree of heart failure: HF 2A - 54 persons, with HF 2B - 66 people. The groups were compared in age, gender, functional class of IHD, severity of AH and HF.Analysis of heart ultrasound showed the following. In IHD in combination with hypertension, complicated by HF 2A, the pressure in the pulmonary artery rises in an average to 46.46 ± 3.64 mm Hg and it increases in HF 2B to 57.00 ± 5.19 mm Hg., that corresponding to the average level of pulmonary hypertension (p<0.01); at the same time, the fraction of ejection of left ventricle in the first patients decreases moderately up to 45.96 ± 2.01%, in others - to 39.93 ± 1.99% (p ˂0.01).In patients with IHD in combination with hypertension complicated by chronic heart failure the structural and functional changes are formed on the side of the left heart, accompanied by an increase in their size due to hypertrophy, formation of stagnant phenomena, regurgitation, functional state disorders by the restrictive type, progressive systolic and diastolic dysfunction, increased pressure in the pulmonary artery.Conclusions. Consideration of pulmonary hypertension, along with other parameters of intracardiac hemodynamics, is an important component in determining the degree and nature of heart failure, which requires the selection of adequate and timely therapeutic tactics.

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