scholarly journals Conformational and Disorder to Order Transitions in Proteins: Structure / Function Correlation in Apolipoproteins

10.5772/37217 ◽  
2012 ◽  
Author(s):  
José Campos-Terán ◽  
Paola Mendoza Espinosa ◽  
Jaime Mas ◽  
Rolando Castillo
Keyword(s):  
Structure Function ◽  
Function Correlation

scholarly journals The structure–function correlation analysed by OCT and full field ERG in typical and pericentral subtypes of retinitis pigmentosa

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ching-Wen Huang ◽  
Jung-Je Yang ◽  
Chang-Hao Yang ◽  
Chung-May Yang ◽  
Fung-Rong Hu ◽  
...  
Keyword(s):  
Retinitis Pigmentosa ◽  
Structure Function ◽  
Subgroup Analysis ◽  
Primary Analysis ◽  
Cross Sectional ◽  
Zone Length ◽  
Full Field ◽  
Multiple Parameters ◽  
Typical Type ◽  
Function Correlation

AbstractTo investigate the structure–function correlation analysed by full-field electroretinography (ffERG) and optical coherence tomography (OCT) in typical and pericentral subtypes of retinitis pigmentosa (RP). A retrospective, cross-sectional, observational study of right eyes was conducted. The primary analysis used ffERG data to compare the RP subtypes. The subgroup analysis was used to correlate the structure, analysed by OCT, and function, determined by ffERG. Linear regressions explored the relationship between best-corrected visual acuity (BCVA) and multiple parameters. A total of 188 eyes were included. Amplitudes of responses of rod, rod-cone, cone, and 30 Hz flicker of typical type were lower than those of pericentral and other types. In the subgroup analysis, 41 and 21 eyes of the typical and pericentral types were studied, respectively. The correlation between the estimated preserved photoreceptor area and all ffERG amplitude parameters were significant in the typical type, but not in pericentral type. Old age, decreased intact ellipsoid zone length, typical type, and thin central retinal thickness were negatively correlated with BCVA. Typical type RP developed more extensive degeneration and poorer BCVA compared to others. Strong structure–function correlation was found in typical type while not in pericentral type. OCT may be a useful tool for monitoring RP status in typical type, providing useful parameters for the prediction of BCVA.

Structure−Function Correlation of Chloroquine and Analogues as Transgene Expression Enhancers in Nonviral Gene Delivery

2006 ◽  
Vol 49 (22) ◽  
pp. 6522-6531 ◽  
Author(s):  
Jianjun Cheng ◽  
Ryan Zeidan ◽  
Swaroop Mishra ◽  
Aijie Liu ◽  
Suzie H. Pun ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Structure Function ◽  
Transgene Expression ◽  
Nonviral Gene Delivery ◽  
Function Correlation

Macromolecular Prodrugs of Ribavirin: Structure–Function Correlation as Inhibitors of Influenza Infectivity

2016 ◽  
Vol 14 (1) ◽  
pp. 234-241 ◽  
Author(s):  
Camilla Frich Riber ◽  
Tracey M. Hinton ◽  
Paulina Gajda ◽  
Kaja Zuwala ◽  
Martin Tolstrup ◽  
...  
Keyword(s):  
Structure Function ◽  
Function Correlation ◽  
Macromolecular Prodrugs

Structure–function correlation of human programmed cell death 5 protein

2009 ◽  
Vol 486 (2) ◽  
pp. 141-149 ◽  
Author(s):  
Hongwei Yao ◽  
Lanjun Xu ◽  
Yingang Feng ◽  
Dongsheng Liu ◽  
Yingyu Chen ◽  
...  
Keyword(s):  
Cell Death ◽  
Programmed Cell Death ◽  
Structure Function ◽  
Function Correlation ◽  
Programmed Cell Death 5

Mechanochromism and aggregation induced emission in benzothiazole substituted tetraphenylethylenes: a structure function correlation

RSC Advances ◽  
2015 ◽  
Vol 5 (38) ◽  
pp. 29878-29884 ◽  
Author(s):  
Thaksen Jadhav ◽  
Bhausaheb Dhokale ◽  
Shaikh M. Mobin ◽  
Rajneesh Misra
Keyword(s):  
Structure Function ◽  
Aggregation Induced Emission ◽  
Function Correlation

The mechanochromic and aggregation induced emission (AIE) properties of benzothiazole (BT) substituted tetraphenylethylene (TPE) 3a–3c were found to be dependent on the linkage between BT and TPE.

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