scholarly journals SATB1: Key Regulator of T Cell Development and Differentiation

10.5772/36303 ◽  
2012 ◽  
Author(s):  
Kamalvishnu P. ◽  
Mithila Burute ◽  
Sanjeev Galande
Keyword(s):  
T Cell ◽  
T Cell Development ◽  
Cell Development ◽  
Development And Differentiation

scholarly journals The Effects of TLR Activation on T-Cell Development and Differentiation

2012 ◽  
Vol 2012 ◽  
pp. 1-32 ◽  
Author(s):  
Bo Jin ◽  
Tao Sun ◽  
Xiao-Hong Yu ◽  
Ying-Xiang Yang ◽  
Anthony E. T. Yeo
Keyword(s):  
T Cells ◽  
T Cell ◽  
Regulatory T Cells ◽  
T Cell Development ◽  
Cell Receptor ◽  
Treg Cells ◽  
Cell Development ◽  
T Cell Subsets ◽  
Follicular Helper ◽  
Development And Differentiation

Invading pathogens have unique molecular signatures that are recognized by Toll-like receptors (TLRs) resulting in either activation of antigen-presenting cells (APCs) and/or costimulation of T cells inducing both innate and adaptive immunity. TLRs are also involved in T-cell development and can reprogram Treg cells to become helper cells. T cells consist of various subsets, that is, Th1, Th2, Th17, T follicular helper (Tfh), cytotoxic T lymphocytes (CTLs), regulatory T cells (Treg) and these originate from thymic progenitor thymocytes. T-cell receptor (TCR) activation in distinct T-cell subsets with different TLRs results in differing outcomes, for example, activation of TLR4 expressed in T cells promotes suppressive function of regulatory T cells (Treg), while activation of TLR6 expressed in T cells abrogates Treg function. The current state of knowledge of regarding TLR-mediated T-cell development and differentiation is reviewed.

scholarly journals β-Catenin/TCF-1 Pathway in T Cell Development and Differentiation

2012 ◽  
Vol 7 (4) ◽  
pp. 750-762 ◽  
Author(s):  
Jian Ma ◽  
Ruiqing Wang ◽  
Xianfeng Fang ◽  
Zuoming Sun
Keyword(s):  
T Cell ◽  
T Cell Development ◽  
Cell Development ◽  
Development And Differentiation

scholarly journals Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation

2014 ◽  
Vol 111 (32) ◽  
pp. E3306-E3315 ◽  
Author(s):  
A. Tsagaratou ◽  
T. Aijo ◽  
C.-W. J. Lio ◽  
X. Yue ◽  
Y. Huang ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Development ◽  
Cell Development ◽  
Dynamic Changes ◽  
Development And Differentiation

scholarly journals Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation

2013 ◽  
Vol 14 (11) ◽  
pp. 1190-1198 ◽  
Author(s):  
Gangqing Hu ◽  
Qingsong Tang ◽  
Suveena Sharma ◽  
Fang Yu ◽  
Thelma M Escobar ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Development ◽  
Noncoding Rnas ◽  
Cell Development ◽  
Long Noncoding Rnas ◽  
Development And Differentiation

scholarly journals Interleukin-4 Regulates Eomesodermin in CD8+ T Cell Development and Differentiation

PLoS ONE ◽  
2014 ◽  
Vol 9 (9) ◽  
pp. e106659 ◽  
Author(s):  
Shannon A. Carty ◽  
Gary A. Koretzky ◽  
Martha S. Jordan
Keyword(s):  
T Cell ◽  
T Cell Development ◽  
Cd8 T Cell ◽  
Cell Development ◽  
Interleukin 4 ◽  
Development And Differentiation
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