scholarly journals The Determination of the Stoichiometry of Cyclodextrin Inclusion Complexes by Spectral Methods: Possibilities and Limitations

10.5772/34287 ◽  
2012 ◽  
Author(s):  
Cristina Tablet ◽  
Iulia Matei ◽  
Mihaela Hillebr
Keyword(s):  
Inclusion Complexes ◽  
Spectral Methods ◽  
Cyclodextrin Inclusion Complexes ◽  
Cyclodextrin Inclusion

Cyclodextrin Inclusion Complexes of Two Non-Steroidal Antiinflammatory Drugs and of an Analgesic Drug

1991 ◽  
Vol 44 (6) ◽  
pp. 855 ◽  
Author(s):  
SE Brown ◽  
JH Coates ◽  
CJ Easton ◽  
SF Lincoln ◽  
Y Luo ◽  
...  
Keyword(s):  
Inclusion Complexes ◽  
Stability Constants ◽  
Analgesic Drug ◽  
Antiinflammatory Drugs ◽  
Cyclodextrin Inclusion Complexes ◽  
Spectral Changes ◽  
Cyclodextrin Inclusion ◽  
Non Steroidal Antiinflammatory Drugs ◽  
The Stability

U.v .-visible spectrophotometric studies of the interactions of Naproxen, Ibuprofen and Panadol with α-cyclodextrin , β-cyclodextrin, γ-cyclodextrin and dimethyl β- cyclodextrin enable the determination of stability constants of inclusion complexes when their formation gives rise to appreciable spectral changes. The magnitudes of the stability constants are discussed in terms of the relative sizes and the chemical natures of the cyclodextrins and the included molecules.

Sign in / Sign up

Export Citation Format

Share Document