scholarly journals Influence of Freeze-Drying and Irradiation on Mechanical Properties of Human Cancellous Bone: Application to Impaction Bone Grafting

Bone Grafting ◽  
10.5772/32811 ◽  
2012 ◽  
Author(s):  
Olivier Cornu
Keyword(s):  
Mechanical Properties ◽  
Cancellous Bone ◽  
Bone Grafting ◽  
Freeze Drying ◽  
Impaction Bone Grafting ◽  
Human Cancellous Bone

Synergetic effect of freeze-drying and gamma irradiation on the mechanical properties of human cancellous bone

2010 ◽  
Vol 12 (4) ◽  
pp. 281-288 ◽  
Author(s):  
Olivier Cornu ◽  
Jérome Boquet ◽  
Olivier Nonclercq ◽  
Pierre-Louis Docquier ◽  
John Van Tomme ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Gamma Irradiation ◽  
Cancellous Bone ◽  
Freeze Drying ◽  
Synergetic Effect ◽  
Human Cancellous Bone

Effect of freeze-drying and gamma irradiation on the mechanical properties of human cancellous bone

2000 ◽  
Vol 18 (3) ◽  
pp. 426-431 ◽  
Author(s):  
O. Cornu ◽  
X. Banse ◽  
P. L. Docquier ◽  
S. Luyckx ◽  
Ch. Delloye
Keyword(s):  
Mechanical Properties ◽  
Gamma Irradiation ◽  
Cancellous Bone ◽  
Freeze Drying ◽  
Human Cancellous Bone

scholarly journals Effect of synthetic bone replacement material of different size on shear stress resistance within impacted native and thermodisinfected cancellous bone: an in vitro femoral impaction bone grafting model

2021 ◽  
Author(s):  
C. Fölsch ◽  
P. Sahm ◽  
C. A. Fonseca Ulloa ◽  
G. A. Krombach ◽  
M. Kampschulte ◽  
...  
Keyword(s):  
Cancellous Bone ◽  
Bone Grafting ◽  
Shear Force ◽  
Distal Region ◽  
Impaction Bone Grafting ◽  
Proximal Point ◽  
Local Antibiotics ◽  
Joint Replacements ◽  
Native Bone

AbstractAntibiotic carrier particles of variable size might influence mechanic properties within impacted thermodisinfected and native cancellous bone different. Herafill®G containing calciumsulfate and calciumcarbonate provides high local concentrations of gentamicin being important for revision surgery in infected joint replacements. Native and thermodisinfected cancellous bone derived from 6 to 7 months old piglets was used for in vitro impaction bone grafting and supplemented each with Herafill®G granules of two different sizes. Micromovement of implants related to shear force was measured in 29 specimens distributed in 6 groups. Thermodisinfected cancellous bone revealed a significant higher shear force resistance than native bone with a mean difference of 423.8 mdeg/Nm (p < 0.001) ranging within 95% confidence interval from 181.5 to 666.0 mdeg/Nm. Adding small granules to thermodisinfected bone did not reduce shear force resistance significantly since adding large granules to native bone improved it by 344.0 mdeg/Nm (p < 0.003). Shear force resistance was found higher at the distal region of the implant compared to a proximal point of measurement throughout all specimens. Less impaction impulses were necessary for thermodisinfected bone. Thermodisinfected cancellous bone might achieve a higher degree of impaction compared with native bone resulting in increased resistance against shear force since impaction was found increased distally. Supplementation of thermodisinfected bone with small granules of Herafill®G might be considered for application of local antibiotics. Large granules appeared more beneficial for supplementation of native bone. Heterogeneity of bone graft and technical aspects of the impaction procedure have to be considered regarding the reproducibility of femoral impaction bone grafting.

Mechanical properties of human cancellous bone in the femoral head

1974 ◽  
Vol 12 (3) ◽  
pp. 313-317 ◽  
Author(s):  
C. M. Schoenfeld ◽  
E. P. Lautenschlager ◽  
P. R. Meyer
Keyword(s):  
Mechanical Properties ◽  
Femoral Head ◽  
Cancellous Bone ◽  
Human Cancellous Bone

Influence of the fixation technique on the mechanical properties of human cancellous bone of the femoral head

2021 ◽  
Vol 82 ◽  
pp. 105280
Author(s):  
Benjamin Fischer ◽  
Alexander Hofmann ◽  
Sascha Kurz ◽  
Melanie Edel ◽  
Dirk Jörg Zajonz ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Femoral Head ◽  
Cancellous Bone ◽  
Fixation Technique ◽  
Human Cancellous Bone

scholarly journals Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0247764
Author(s):  
Chenglong Shi ◽  
Nana Lu ◽  
Yaru Qin ◽  
Mingdi Liu ◽  
Hongxia Li ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Pore Size ◽  
Cancellous Bone ◽  
Simulation Analysis ◽  
Porous Scaffold ◽  
Angle Distribution ◽  
Artificial Bone ◽  
Mechanical Compression ◽  
Human Cancellous Bone ◽  
Computational Fluid Dynamics Cfd

In this paper, we take the elliptical pore structure which is similar to the microstructure of cancellous bone as the research object, four groups of bone scaffolds were designed from the perspective of pore size, porosity and pore distribution. The size of the all scaffolds were uniformly designed as 10 × 10 × 12 mm. Four groups of model samples were prepared by selective laser melting (SLM) and Ti6Al4V materials. The statics performance of the scaffolds was comprehensively evaluated by mechanical compression simulation and mechanical compression test, the manufacturing error of the scaffold samples were evaluated by scanning electron microscope (SEM), and the permeability of the scaffolds were predicted and evaluated by simulation analysis of computational fluid dynamics (CFD). The results show that the different distribution of porosity, pore size and pores of the elliptical scaffold have a certain influence on the mechanical properties and permeability of the scaffold, and the reasonable size and angle distribution of the elliptical pore can match the mechanical properties and permeability of the elliptical pore scaffold with human cancellous bone, which has great potential for research and application in the field of artificial bone scaffold.

scholarly journals Mechanical Loading Causes Detectable Changes in Morphometric Measures of Trabecular Structure in Human Cancellous Bone

2013 ◽  
Vol 135 (5) ◽  
Author(s):  
Yener N. Yeni ◽  
Brenda Wu ◽  
Lily Huang ◽  
Daniel Oravec
Keyword(s):  
Mechanical Properties ◽  
Cancellous Bone ◽  
Coefficient Of Variation ◽  
Bone Microstructure ◽  
Strain History ◽  
Mechanical Loads ◽  
Bone Mechanical Properties ◽  
Custom Made ◽  
Human Cancellous Bone ◽  
Trabecular Number

The relationships between mechanical loads and bone microstructure are of interest to those who seek to predict bone mechanical properties from microstructure or to predict how organization of bone microstructure is driven by mechanical loads. While strains and displacements in the material are inherently responsible for mechanically caused changes in the appearance of the microstructure, it is the morphometric measures of microstructural organization that are often available for assessment of bone quality. Therefore, an understanding of how strain history is reflected in morphometric measures of bone microstructure has practical implications in that it may provide clinically measurable indices of mechanical history in bone and improve interpretation of bone mechanical properties from microstructural information. The objective of the current study was to examine changes in morphometric measures of cancellous bone microstructure in response to varying levels of continuum level strains. The experimental approach included stereologic analysis of microcomputed tomography (μCT) images of human cancellous bone samples obtained at sequentially increasing levels of strain in a custom-made loading apparatus mounted in a μCT scanner. We found that the degree of anisotropy (DA) decreased from baseline to failure and from failure to postfailure. DA partially recovered from postfailure levels upon unloading; however, the final DA was less than at failure and less than at baseline. We also found that average trabecular thickness (Tb.Th.Av) increased with displacements at postfailure and did not recover when unloaded. Average trabecular number decreased when the specimens were unloaded. In addition, the heterogeneity of Tb.Th as measured by intra-specimen standard deviation (Tb.Th.SD) increased and that of trabecular number (Tb.N.SD) decreased with displacements at postfailure. Furthermore, the intraspecimen coefficient of variation of trabecular number decreased at postfailure displacements but did not recover upon unloading. Finally, the coefficient of variation of trabecular separation at unload was less than that at baseline. These measures can be developed into image-based indices to estimate strain history, damage, and residual mechanical properties where direct analysis of stresses and strains, such as through finite element modeling, may not be feasible. It remains to be determined how wide a time interval can be used to estimate strain history before remodeling becomes an overriding effect on the trabecular architecture.

scholarly journals The Weibull Distribution on Reliability Evaluation of Mechanical Property for Impaction Bone Grafting

2020 ◽  
Author(s):  
Mumingjiang Yishake ◽  
Lan Tang ◽  
Chenyi Ye ◽  
Rongxin He
Keyword(s):  
Mechanical Properties ◽  
Weibull Distribution ◽  
Bone Grafting ◽  
Elastic Moduli ◽  
High Reliability ◽  
Bone Grafts ◽  
Impaction Bone Grafting ◽  
Large Bone

Abstract Background: The mechanical properties of bone grafts used to reconstruct defects during revision surgery, and their long-term reliability, are important in terms of treatment outcomes. However, few relevant studies have appeared. Herein, we use a new method, the Weibull distribution, to evaluate reliability.Methods: We created impacted bone grafts of two distinct sizes (7–10 mm and small slurry) using an impacting apparatus. The elastic moduli were evaluated in vitro and the Weibull moduli (m values) were calculated.Results: The elastic moduli fitted the Weibull distribution well. Large bone grafts (7–10 mm) exhibited high elastic moduli but low Weibull moduli, suggestive of poor reliability.Conclusions: The Weibull distribution was useful to evaluate the reliability of bone graft mechanical properties. A high Weibull modulus indicated high reliability and thus low variability. Both the values and reliability of mechanical properties must be considered when contemplating bone grafting.

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