scholarly journals Perinatal Mortality in Multiple Pregnancy

10.5772/32441 ◽  
2012 ◽  
Author(s):  
Patricia Steenhaut ◽  
Corinne Hubinont
Keyword(s):  
Perinatal Mortality ◽  
Multiple Pregnancy

Preterm labour in multiple pregnancies

1993 ◽  
Vol 5 (2) ◽  
pp. 105-119 ◽  
Author(s):  
James P Neilson ◽  
Caroline A Crowther
Keyword(s):  
Perinatal Mortality ◽  
Preterm Labour ◽  
Multiple Pregnancy ◽  
High Rate ◽  
Fetal Malformation ◽  
Multiple Pregnancies ◽  
Neonatal Deaths ◽  
Late Abortion ◽  
Early Neonatal Deaths ◽  
Singleton Pregnancies

Multiple pregnancy is associated with a high rate of perinatal loss – mainly due to preterm labour but with important contributions from fetal malformation, intrauterine growth retardation and twin-twin transfusion syndrome. The overall perinatal mortality rate is consistently around six times that of singleton pregnancies but the rate rises progressively with the number of fetuses. Rates of 63,164,200,214 and 416 per 1000 births have been recently reported for twins, triplets, quadruplets, quintuplets and sextuplets respectively. In addition to these alarming figures, it should be emphasized that the restricted concept of perinatal mortality obscures the real extent of loss. If we include late abortion (after 20 weeks), late neonatal deaths and deaths in infancy from perinatal causes, as well as the usual indices of perinatal mortality (stillbirths and early neonatal deaths) we find that the total loss rate from twin pregnancy alone doubles and may be close to 10%. Although the rate of loss from multiple pregnancies is now substantially higher than that associated with the pregnancies of diabetic women, the challenge of multiple pregnancy has not been met with the same commitment or organisation of specialized perinatal services as has diabetes.

scholarly journals Comparative study of vaginal delivery and caesarean section in antepartum eclampsia at tertiary care hospital

2017 ◽  
Vol 6 (2) ◽  
pp. 457 ◽  
Author(s):  
Priti Kumari ◽  
Sipra Singh ◽  
Salma Khatun ◽  
. Shashikar
Keyword(s):  
Caesarean Section ◽  
Perinatal Mortality ◽  
Vaginal Delivery ◽  
Tertiary Care ◽  
Mode Of Delivery ◽  
Multiple Pregnancy ◽  
Fetal Outcome ◽  
Sudden Onset ◽  
Care Hospital ◽  
Maternal Complications

Background: Eclampsia is characterized by the sudden onset of generalized tonic clonic seizures. Eclampsia is usually preceded by a history of the pre-eclampsia but rarely arises in a woman with minimally increased blood pressure and no proteinuria. Eclampsia most commonly occurs in the third trimester, though rarely eclampsia may occur before 20 wks in molar or multiple pregnancy. The aim of the study was to compare maternal and fetal outcome in antepartum eclampsia when terminated by vaginal delivery and caesarean section.Methods: 50 women with eclampsia attending emergency department OBG department of Katihar Medical College, Katihar were collected from Feb 2015 to Sep 2016. Depending upon the mode of delivery, they were divided into two groups, CD group where caesarean section was performed and VD group where vaginal delivery was performed.Results: Of the 50 cases, caesarean section was done in 40% of the cases, while vaginal delivery was carried was carried in 60%.Maternal complications in CD group was 35% and 80% in VD group (p<0.001).The incidence of live births, still birth and neonatal death was 85%, 15%, 0% in CD group and 60%, 40%, 10% in VD group. The corrected perinatal mortality was 50%.Conclusions: Timely caesarean section reduces maternal and perinatal mortality and improves their outcome in antepartum eclampsia.

scholarly journals Antenatal fetal death in multiple pregnancy: is early prediction possible?

2021 ◽  
Vol 14 (6) ◽  
pp. 602-611
Author(s):  
V. I. Tsibizova ◽  
D. V. Blinov ◽  
V. O. Bitsadze ◽  
T. M. Pervunina ◽  
E. V. Komlichenko ◽  
...  
Keyword(s):  
Perinatal Mortality ◽  
Reference Values ◽  
Fetal Death ◽  
Multiple Pregnancy ◽  
First Trimester ◽  
Multiple Pregnancies ◽  
Vitro Fertilization ◽  
Diagnostic Potential ◽  
Increased Risk

Introduction. Perinatal mortality in multiple pregnancies increases by 8–10 times compared to singletons. Stillbirth is a significant part of all complications of multiple pregnancies. Although the incidence of perinatal mortality in multiple pregnancies has decreased consistently compared to extremely high rates in the past, it remains relatively high, despite significant positive changes in the management of such pregnancies. Aim: to assess the diagnostic potential of the first trimester's biochemical screening in multiple pregnancies for predicting antenatal fetal death. Materials and Methods. As part of a retrospective study, a cohort of twin pregnancies after in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), or spontaneous conception underwent screening of the first trimester at 11+0–13+6 weeks of gestation as recommended by the Fetal Medicine Foundation. Determination of pregnancy-associated plasma protein-A (PAPP-A) in blood serum with subsequent calculation of the relative PAPP-A MoM (multiples of median) – a multiple of the median (an indicator of how much the individual test result deviates from the reference values) was performed. Results. Prenatal screening and outcomes of 302 multiple pregnancies showed that with PAPP-A MoM < 0.5, antenatal fetal death occurred with a frequency of 42.86 % (6/14), with PAPP-A MoM within the reference values – In 12.67 % (28/221), with PAPP-A MoM > 2.0 – in 6.7 % (2/30). Differences between patients with PAPP-A MoM < 0.5 and PAPP-A MoM within the reference values, as well as PAPP-A MoM < 0.5 and PAPP-A MoM > 2.0 were statistically significant (p = 0.002 and p = 0.004, respectively). No differences were detected between spontaneous and assisted reproductive technology (ART) pregnancies. Conclusion. In women with multiple pregnancies resulting from ART or spontaneous, PAPP-A MoM values below the reference interval (< 0.5) in the first trimester are associated with an increased risk of antenatal fetal death.

scholarly journals PP.12 Weight Discordance and Perinatal Mortality in Twins: The Stork Multiple Pregnancy Cohort

2013 ◽  
Vol 98 (Suppl 1) ◽  
pp. A85.2-A85
Author(s):  
F D’Antonio ◽  
A Khalil ◽  
T Dias ◽  
A Bhide ◽  
B Thilaganathan
Keyword(s):  
Perinatal Mortality ◽  
Multiple Pregnancy ◽  
Pregnancy Cohort

Perinatal Mortality in Multiple Pregnancy Patients

1988 ◽  
Vol 37 (3-4) ◽  
pp. 331-337 ◽  
Author(s):  
F.P. Meehan ◽  
I.M. Magani ◽  
G. Mortimer
Keyword(s):  
Mortality Rate ◽  
Perinatal Mortality ◽  
Low Birthweight ◽  
Multiple Pregnancy ◽  
Fetal Loss ◽  
External Cephalic Version ◽  
Elective Cesarean Section ◽  
Regional Analgesia ◽  
Perinatal Mortality Rate ◽  
Second Twin

AbstractA study of perinatal mortality in multiple pregnancy over a period of 12 years, 1972 to 1984, showed prematurity and low birthweight as the major causes of fetal loss. The highest risk was found at 28 to 30 weeks gestation (306/1,000). There was a significantly greater risk to babies delivered by the breech (136/1,000), and likewise in the second twin when compared with the first, ratio 1:1.4. A significant drop in the perinatal mortality rate, from 98/1,000 to 39/1,000, was observed between 1972-1978 and 1979-1984. Ultrasound has facilitated the earlier diagnosis of twins and provides more accurate serial fetal assessment. Bedrest, more vigilant antenatal care, intrapartum surveillance and improved neonatal care, are required to maintain and further reduce the perinatal mortality rate. When regional analgesia was employed in labour, the number of babies lost was 41/1,000, vs 93/1,000 in patients not receiving regional analgesia. External cephalic version and vertex delivery of the second twin is preferable to internal version and breech extraction. It should also be contemplated, as an alternative to elective cesarean section for a transverse lie or brrech presentation of the second fetus.

scholarly journals Weight discordance and perinatal mortality in monoamniotic twin pregnancy: analysis of MONOMONO, NorSTAMP and STORK multiple‐pregnancy cohorts

2020 ◽  
Vol 55 (3) ◽  
pp. 332-338 ◽  
Author(s):  
G. Saccone ◽  
A. Khalil ◽  
B. Thilaganathan ◽  
S. V. Glinianaia ◽  
V. Berghella ◽  
...  
Keyword(s):  
Perinatal Mortality ◽  
Twin Pregnancy ◽  
Multiple Pregnancy

Amnion Nodosum Revisited: Clinicopathologic and Placental Correlations

2007 ◽  
Vol 131 (12) ◽  
pp. 1829-1833
Author(s):  
Adebowale J. Adeniran ◽  
Jerzy Stanek
Keyword(s):  
Granular Material ◽  
Perinatal Mortality ◽  
Clinical Features ◽  
Gestational Age ◽  
Multiple Pregnancy ◽  
Control Group ◽  
Study Group ◽  
Chorionic Villi ◽  
Vascular Abnormalities

Abstract Amnion nodosum is commonly regarded as a placental hallmark of severe and prolonged oligohydramnios. It consists of nodules of amorphous granular material present on the surface of the amnion. We reviewed all 45 cases of amnion nodosum from our placental database from 1994 through 2003 (study group). The control group consisted of 45 cases from the same database matched for gestational age but without amnion nodosum. Oligohydramnios, multiple pregnancy, perinatal mortality, macerated stillbirths, and chronic twin-twin transfusion were the most common clinical features encountered in the study group. Luminal vascular abnormalities of chorionic villi, fibrosis of chorionic villi, and placental edema were the placental features that were more frequently present in the study group.

Sign in / Sign up

Export Citation Format

Share Document