scholarly journals The Role of the Pap Smear Diagnosis: Atypical Glandular Cells (AGC)

10.5772/31971 ◽  
2012 ◽  
Author(s):  
Chiung-Ru Lai ◽  
Chih-Yi Hsu ◽  
Anna Fen-Yau
Keyword(s):  
Pap Smear ◽  
Glandular Cells ◽  
Atypical Glandular Cells

scholarly journals Comparison of the Histologic Results of Atypical Glandular Cells-Favor Neoplasia and Atypical Glandular Cells-Not Otherwise Specified

2016 ◽  
Vol 22 (1) ◽  
Author(s):  
Alper Karalök ◽  
Özgür Koçak ◽  
Tolga Taşçı ◽  
Bülent Yırcı ◽  
Işın Üreyen ◽  
...  
Keyword(s):  
Pap Smear ◽  
Screening Tests ◽  
Cytologic Examination ◽  
Screening Programs ◽  
Not Otherwise Specified ◽  
Significant Difference ◽  
Risk Of Malignancy ◽  
Glandular Cells ◽  
Atypical Glandular Cells ◽  
Group A

<p>Objective: Cervical cancer screening programs are widely performed in all around the world. The interpretation of the Pap smear test is a big challenge in gynecology practice particularly when associated with atypical glandular cells. In this study, we performed a retrospective analysis of cytologic results associated with atypical glandular cells in our institution.<br />Material and Method: We retrospectively reviewed Pap smear tests resulted as “atypical glandular cells”. A total of 122 women had screening tests reported as “atypical glandular cells” between 2003 and 2013 at the Ministry of Health, Etlik Maternity and Women’s Health Teaching Research. The cytology reported as “atypical glandular cells” were evaluated in two main groups: Atypical glandular cells-favor neoplasia (AGC-FN) and atypical glandular cells-not otherwise specified (AGC-NOS) compared by means of histologic results.<br />Results: Thirty-two women have been reported as AGC-NOS on cytologic examination and 90 women were defined as AGC-FN. There was no significant difference between AGC-FN and AGC NOS groups in terms of age. In AGC-FN group, a total of 13 women (13/90) (14.4%) had malignant histological diagnosis. In AGC-NOS group only one woman (1/32) (3.1%) was diagnosed as malignant. All the malignant cases in this study are older than 35 years.<br />Conclusion: The incidence of AGC is less than 1% in all Pap smear examinations. Two main factors were important in the outcome of the AGC. The first one is the subgroup. AGC-FN group has a higher risk of malignancy. The second important factor is the age of the patient. To be older than 35 years old seems to increase the risk of malignancy.<br /><br /></p>

The Diagnostic Value of Routine Papanicolaou Smears for Detecting Endometrial Cancers: An Update

2015 ◽  
Vol 59 (4) ◽  
pp. 315-318 ◽  
Author(s):  
Chiung-Ru Lai ◽  
Chih-Yi Hsu ◽  
Jen-Fan Hang ◽  
Anna Fen-Yau Li
Keyword(s):  
Pap Smear ◽  
Diagnostic Value ◽  
Routine Screening ◽  
Pap Smears ◽  
Cervical Lesions ◽  
Endometrial Cells ◽  
Glandular Cells ◽  
Atypical Glandular Cells ◽  
Endometrial Cancers ◽  
New Criteria

Objective: The presence of degenerative endometrial debris and abnormal endometrial cells is considered to be the hint for endometrial pathology. The purpose of this study was to evaluate the efficacy of Papanicolaou (Pap) smears in detecting endometrial cancers. Study Design: There were 146 cases of endometrial cancer diagnosed at our institute in 2000-2002 and 271 in 2010-2012. Among them, 57 and 95 relevant reports of Pap smears 6 months prior to the histology diagnosis were retrieved for this study, respectively. In the first time period, new criteria for detecting endometrial lesions had not yet been incorporated into routine screening. Results: Twenty cases (21%) of adenocarcinoma, 12 (13%) of atypical glandular cells, 4 (4%) of endometrial debris and 59 (62%) negative reports were found among the more recent 95 relevant Pap smears. The overall efficacy of the Pap smear for detecting endometrial malignancy was 38%, higher than 10 years previously (30%). Conclusion: Although the Pap smear was originally designed to screen cervical lesions, more effective detection of endometrial lesions could be achieved by adding new criteria to the routine screening.

scholarly journals Atypical glandular cells in pap smear as a primarily presentation of ovarian serous borderline tumor

2021 ◽  
Vol 49 (2-3) ◽  
pp. 138-142
Author(s):  
Danijela Jurič ◽  
Ana Barišić ◽  
Sanda Rajhvajn ◽  
Vesna Mahovlić ◽  
Davor Petrović ◽  
...  
Keyword(s):  
Pap Smear ◽  
Borderline Tumor ◽  
Serous Borderline Tumor ◽  
Glandular Cells ◽  
Atypical Glandular Cells

scholarly journals The value of Pap test in women with endometrial cancer

2011 ◽  
Vol 1 (3) ◽  
pp. 122-125
Author(s):  
Aleksandra Petrić ◽  
Vekoslav Lilić ◽  
Radomir Živadinović ◽  
Predrag Vukomanović ◽  
Olivera Dunjić ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Pap Smear ◽  
Statistical Significance ◽  
Menopausal Status ◽  
Screening Method ◽  
Pap Test ◽  
Transvaginal Sonography ◽  
Glandular Cells ◽  
Atypical Glandular Cells ◽  
The Difference

Introduction: Endometrial cancer is the second most common gynecological tumor. There is still no recommended screening method for endometrial cancer. The application of transvaginal sonography, hysteroscopy and Pap test may prove useful in screening for this disease. Atypical glandular cells represent an important finding in Pap tests and they are related to histopathological verification of the endometrium. The aim of the study was to determine the usefulness of the Pap test in assessing the cervical infiltration, as well as to determine the significance of hormonal status and histopathological type of tumor in a pathological Pap test in patients with endometrial cancer.Methods: The study was retrospective. The analysis included the data obtained from 62 operated patients diagnosed with enometrial cancer, medical history (menopausal status), histopathological findings after surgery (type and stage of the disease) and a preoperative Pap smear. The chi squared and Fisher’s test were used.Results: The difference in the prevalence of pathological Pap test in premenopausal and postmenopausal group of patients was not statistically significant. The difference in the prevalence of pathological Pap test in the group of endometrioid and non-endometrioid tumours of the uterine corpus had statistical significance. The difference in the prevalence of pathological Pap test compared to the present stage (I and II) was not statistically significant.Conclusion: Pap smear does not correlate with menopausal status in women with endometrial carcinoma. Abnormal Pap test is more commonly found in cases of non-endometroid tumours. Pap smears cannot beused to assess cervical involvement.

Clinical significance of atypical glandular cells on Pap smear

2006 ◽  
Vol 17 (4) ◽  
pp. 279
Author(s):  
Eun Kyoung Shin ◽  
Mi Kyoung Kim ◽  
You Jung Han ◽  
Soo Yoon Lee ◽  
Woong Ju ◽  
...  
Keyword(s):  
Clinical Significance ◽  
Pap Smear ◽  
Glandular Cells ◽  
Atypical Glandular Cells
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