scholarly journals Targeting Molecular Pathways for Prevention of High Risk Breast Cancer: A Model for Cancer Prevention

10.5772/31700 ◽  
2012 ◽  
Author(s):  
Shayna Showalter ◽  
Brian J.
Keyword(s):  
Breast Cancer ◽  
High Risk ◽  
Cancer Prevention ◽  
Molecular Pathways ◽  
High Risk Breast Cancer ◽  
High Risk Breast ◽  
Risk Breast Cancer

Are ATM Mutations 7271T→G and IVS10-6T→G Really High-Risk Breast Cancer-Susceptibility Alleles?

2004 ◽  
Vol 64 (3) ◽  
pp. 840-843 ◽  
Author(s):  
Csilla I. Szabo ◽  
Mieke Schutte ◽  
Annegien Broeks ◽  
Jeanine J. Houwing-Duistermaat ◽  
Yvonne R. Thorstenson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
High Risk ◽  
Cancer Susceptibility ◽  
Breast Cancer Susceptibility ◽  
High Risk Breast Cancer ◽  
High Risk Breast ◽  
Risk Breast Cancer

Abstract PS1-06: High-risk breast cancer in oldest old: Exploring the effect of different treatments on outcomes

2021 ◽  
Author(s):  
Abdulla Al-Rashdan ◽  
Yuan Xu ◽  
Lisa Barbera ◽  
Jeffrey Cao ◽  
Winson Cheung ◽  
...  
Keyword(s):  
Breast Cancer ◽  
High Risk ◽  
Oldest Old ◽  
High Risk Breast Cancer ◽  
High Risk Breast ◽  
Risk Breast Cancer

Predicting reattendance at a high-risk breast cancer clinic

2015 ◽  
Vol 13 (5) ◽  
pp. 1441-1448 ◽  
Author(s):  
Sarah R. Ormseth ◽  
David K. Wellisch ◽  
Adam E. Aréchiga ◽  
Taylor L. Draper
Keyword(s):  
Breast Cancer ◽  
High Risk ◽  
Perceived Risk ◽  
Depressive Symptomatology ◽  
High Risk Breast Cancer ◽  
High Risk Breast ◽  
Risk Breast Cancer ◽  
Cancer Clinic ◽  
High Risk Clinic

AbstractObjective:The research about follow-up patterns of women attending high-risk breast-cancer clinics is sparse. This study sought to profile daughters of breast-cancer patients who are likely to return versus those unlikely to return for follow-up care in a high-risk clinic.Method:Our investigation included 131 patients attending the UCLA Revlon Breast Center High Risk Clinic. Predictor variables included age, computed breast-cancer risk, participants' perceived personal risk, clinically significant depressive symptomatology (CES–D score ≥ 16), current level of anxiety (State–Trait Anxiety Inventory), and survival status of participants' mothers (survived or passed away from breast cancer).Results:A greater likelihood of reattendance was associated with older age (adjusted odds ratio [AOR] = 1.07, p = 0.004), computed breast-cancer risk (AOR = 1.10, p = 0.017), absence of depressive symptomatology (AOR = 0.25, p = 0.009), past psychiatric diagnosis (AOR = 3.14, p = 0.029), and maternal loss to breast cancer (AOR = 2.59, p = 0.034). Also, an interaction was found between mother's survival and perceived risk (p = 0.019), such that reattendance was associated with higher perceived risk among participants whose mothers survived (AOR = 1.04, p = 0.002), but not those whose mothers died (AOR = 0.99, p = 0.685). Furthermore, a nonlinear inverted “U” relationship was observed between state anxiety and reattendance (p = 0.037); participants with moderate anxiety were more likely to reattend than those with low or high anxiety levels.Significance of Results:Demographic, medical, and psychosocial factors were found to be independently associated with reattendance to a high-risk breast-cancer clinic. Explication of the profiles of women who may or may not reattend may serve to inform the development and implementation of interventions to increase the likelihood of follow-up care.

Sign in / Sign up

Export Citation Format

Share Document