scholarly journals Cardiovascular Disease in Inflammatory Disorders - Psoriasis and Psoriatic Arthritis

10.5772/31651 ◽  
2012 ◽  
Author(s):  
Aizuri Murad ◽  
Anne-Marie Tobi
Keyword(s):  
Cardiovascular Disease ◽  
Psoriatic Arthritis ◽  
Inflammatory Disorders

An Investigation of Comorbid Disease and Health Service Utilization Among Patients With Moderate to Severe Psoriasis in Newfoundland and Labrador

2018 ◽  
Vol 23 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Wayne P. Gulliver ◽  
Shane Randell ◽  
Susanne Gulliver ◽  
Don Macdonald ◽  
Valerie Gregory ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Psoriatic Arthritis ◽  
Newfoundland And Labrador ◽  
Skin Condition ◽  
Biologic Drugs ◽  
Biologic Treatment ◽  
Cross Sectional ◽  
Hospital Stays ◽  
Inflammatory Bowel ◽  
Systemic Therapies

Psoriasis is an inflammatory skin condition affecting 2% to 3% of the population and is associated with several comorbidities, including cardiovascular disease, depression, inflammatory bowel disease, metabolic syndrome, mood disorder, psoriatic arthritis, and weight gain. Psoriasis is treated with a number of topical and systemic therapies, including biologic drugs that directly target proinflammatory cytokines. This cross-sectional retrospective study investigated comorbid conditions reported in the Newfoundland and Labrador psoriasis population, outcomes associated with therapeutic treatment, and use of health care resources. Of the psoriasis comorbidities investigated, psoriatic arthritis was significantly associated with the use of biologic therapy while a failure to respond to biologics was associated with a higher incidence of cardiovascular disease. Patients responsive to biologic treatment had fewer hospital stays than patients treated with other therapies. Our results suggest that biologic therapies have a cardioprotective effect and reduce the number of hospital visits in patients whose symptoms are responsive to treatment.

Strategies for Biomarker Development in Psoriatic Disease: A Report from the GRAPPA 2010 Annual Meeting

2012 ◽  
Vol 39 (2) ◽  
pp. 423-426 ◽  
Author(s):  
CHRISTOPHER T. RITCHLIN
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Psoriatic Arthritis ◽  
Psoriatic Disease ◽  
Funding Sources ◽  
Inflammatory Bowel ◽  
Biomarker Research ◽  
Anxiety Depression ◽  
Collaborative Efforts ◽  
Musculoskeletal Involvement

Psoriatic disease includes psoriasis and associated comorbidities (arthritis, uveitis, inflammatory bowel disease, cardiovascular disease, metabolic syndrome, and anxiety/depression) and is remarkably diverse in disease presentation and course. The marked heterogeneity of musculoskeletal involvement in psoriatic arthritis (PsA) presents major challenges to clinicians regarding diagnosis, risk stratification, and management. Members of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) have begun collaborative efforts to develop biomarkers that can assist in the diagnosis and management of patients with psoriasis and related comorbidities. This brief review provides a rationale for biomarker research in PsA, consideration of types and sources of biomarkers, and examples of important biomarker studies in PsA, followed by a review of trial designs for biomarker research and a discussion of potential funding sources.

Risk of type 2 diabetes and cardiovascular disease in an incident cohort of people with psoriatic arthritis: a population-based cohort study

Rheumatology ◽  
2018 ◽  
Vol 58 (1) ◽  
pp. 144-148 ◽  
Author(s):  
Rachel Charlton ◽  
Amelia Green ◽  
Gavin Shaddick ◽  
Julia Snowball ◽  
Alison Nightingale ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Cohort Study ◽  
Psoriatic Arthritis ◽  
Population Based ◽  
Incident Cohort

scholarly journals Cutaneous and Systemic Psoriasis: Classifications and Classification for the Distinction

2021 ◽  
Vol 8 ◽  
Author(s):  
Bing-Xi Yan ◽  
Xue-Yan Chen ◽  
Li-Ran Ye ◽  
Jia-Qi Chen ◽  
Min Zheng ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Psoriatic Arthritis ◽  
Inflammatory Disease ◽  
Bowel Disease ◽  
Cutaneous Manifestation ◽  
Brain Diseases ◽  
World Population ◽  
The World ◽  
Erythematous Plaques

Psoriasis is a chronic multisystem inflammatory disease that affects ~0.1–1.5% of the world population. The classic cutaneous manifestation of psoriasis is scaly erythematous plaques, limited or widely distributed. Moreover, psoriasis could be associated with comorbidities like psoriatic arthritis, metabolic syndrome, diabetes, cardiovascular disease, nephropathy, bowel disease, and brain diseases. In this review, we suggest that psoriasis should be classified as cutaneous psoriasis or systemic psoriasis and propose the classification for distinction. This would help to better understand and manage psoriasis.

Sign in / Sign up

Export Citation Format

Share Document