scholarly journals Human Papilloma Virus and Anal Cancer

10.5772/31135 ◽  
2012 ◽  
Author(s):  
Joo Batista de Sousa ◽  
Leonardo de Castro Dures
Keyword(s):  
Human Papilloma Virus ◽  
Anal Cancer ◽  
Papilloma Virus

The Incidence and Prevalence of Human Papilloma Virus–associated Cancers in IBD

2020 ◽  
Vol 27 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Jonathan P Segal ◽  
Alan Askari ◽  
Susan K Clark ◽  
Ailsa L Hart ◽  
Omar D Faiz
Keyword(s):  
Inflammatory Bowel Disease ◽  
Human Papilloma Virus ◽  
Anal Cancer ◽  
Bowel Disease ◽  
Cox Regression ◽  
Population Data ◽  
Population Based ◽  
Papilloma Virus ◽  
Cox Regression Analysis ◽  
Inflammatory Bowel

Abstract Aim The human papilloma virus has been associated with anal, cervical, vaginal, and penile cancers. The primary aim of this population-based study is to determine whether HPV-associated cancers are more commonplace in patients with inflammatory bowel disease (IBD). Method The Hospital Episode Statistics (HES) database from 1997 to 2012, linked with officer for age standardized rates (ASR), were calculated using population data, and Cox regression analysis was used to determine whether IBD patients have poorer survival compared with non-IBD patients. Results A total of 61,648 patients were included in this study; of these, 837 patients had a preexisting diagnosis of IBD (1.4%). Inflammatory bowel disease patients had a significantly higher ASR of anal cancers than the non-IBD population: 5.5 per 100,000 in the IBD group compared with 1.8 in the non-IBD group. The IBD group was also diagnosed with anal cancers at a younger age (60 years compared with 66 years in the non-IBD group, P < 0.001). The survival of IBD patients with anal cancer was also poorer than the non-IBD group (hazard ratio, 1.32; 95% confidence interval, 1.15–1.52; P < 0.001). On average, survival was significantly shorter in the IBD group with anal cancer (46 months) compared with the non-IBD group (61 months, P < 0.001). Age standardized rates for cervical cancer was significantly higher in the IBD group (5.2 of 100,000) compared with the non-IBD group (4.6 of 100,000 P = 0.042). Conclusion Patients with IBD have a higher rate of anal cancer compared with the general population. Survival is also worse for anal cancers in the IBD group.

scholarly journals Human Papilloma Virus Infection and Anal Cancer in Kidney Transplant Recipient

2019 ◽  
Vol 7 (5) ◽  
pp. 60
Author(s):  
Kmar Mnif ◽  
Soumaya Yaich ◽  
Fatma Fendri ◽  
Abdelrahmen Masmoudi ◽  
Khaled Charfeddine ◽  
...  
Keyword(s):  
Virus Infection ◽  
Transplant Recipient ◽  
Human Papilloma Virus ◽  
Kidney Transplant ◽  
Anal Cancer ◽  
Kidney Transplant Recipient ◽  
Human Papilloma Virus Infection ◽  
Papilloma Virus

EP-1942: Human papilloma virus status impact upon the full tumor response for treatment anal cancer

2014 ◽  
Vol 111 ◽  
pp. S337
Author(s):  
M. Chernykh ◽  
I. Gladilina ◽  
O. Kozlov ◽  
A. Trigolosov ◽  
M. Nechushkin ◽  
...  
Keyword(s):  
Human Papilloma Virus ◽  
Anal Cancer ◽  
Tumor Response ◽  
Papilloma Virus ◽  
Human Papilloma Virus Status

scholarly journals Human Papilloma Virus and Squamous Cell Carcinoma of the Anus

2014 ◽  
Vol 8 ◽  
pp. CMO.S13241 ◽  
Author(s):  
Bhavna Gami ◽  
Faris Kubba ◽  
Paul Ziprin
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papilloma Virus ◽  
Cell Carcinoma ◽  
Anal Cancer ◽  
Squamous Cell ◽  
Organ Transplant ◽  
Intraepithelial Neoplasia ◽  
Papilloma Virus ◽  
Sex With Men ◽  
The Uk

The incidence of anal cancer is increasing. In the UK, the incidence is estimated at approximately 1.5 per 100,000. Most of this increase is attributed to certain at-risk populations. Persons who are human immunodeficiency virus (HIV)–positive and men who have sex with men (MSM), Organ transplant recipients, women with a history of cervical cancer, human papilloma virus (HPV), or cervical intraepithelial neoplasia (CIN) are known to have a greater risk for anal cancer. This paper will focus on HPV as a risk factor for anal intraepithelial neoplasia (AIN) and discusses the etiology, anatomy, pathogenesis, management of squamous cell carcinoma (SCC) of the anus.

scholarly journals Human papilloma virus load and PD-1/PD-L1, CD8+ and FOXP3 in anal cancer patients treated with chemoradiotherapy: Rationale for immunotherapy

2017 ◽  
Vol 6 (3) ◽  
pp. e1288331 ◽  
Author(s):  
Panagiotis Balermpas ◽  
Daniel Martin ◽  
Ulrike Wieland ◽  
Margret Rave-Fränk ◽  
Klaus Strebhardt ◽  
...  
Keyword(s):  
Human Papilloma Virus ◽  
Cancer Patients ◽  
Anal Cancer ◽  
Papilloma Virus ◽  
Virus Load

E6 and E7 oncogene expression by human papilloma virus (HPV) and the aggressive behavior of recurrent laryngeal papillomatosis (RLP)

2006 ◽  
Vol preprint (2007) ◽  
pp. 1
Author(s):  
Bahig Shehata ◽  
Kristen Otto ◽  
Steven Sobol ◽  
Christina Stockwell ◽  
Cora Foulks ◽  
...  
Keyword(s):  
Human Papilloma Virus ◽  
Aggressive Behavior ◽  
Laryngeal Papillomatosis ◽  
Papilloma Virus ◽  
Oncogene Expression ◽  
E6 And E7 ◽  
E7 Oncogene
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