scholarly journals Role of Growth Factor Receptors in Neural Stem Cells Differentiation and Dopaminergic Neurons Generation

10.5772/31099 ◽  
2012 ◽  
Author(s):  
Luca Calatrava ◽  
Rafael Gonzalo-Gobernado ◽  
Antonio S. ◽  
Diana Reimers ◽  
Maria J. ◽  
...  
Keyword(s):  
Stem Cells ◽  
Growth Factor ◽  
Neural Stem Cells ◽  
Dopaminergic Neurons ◽  
Growth Factor Receptors

scholarly journals Role of Fibroblast Growth Factor Receptors in Astrocytic Stem Cells

2012 ◽  
Vol 7 (1) ◽  
pp. 81-86 ◽  
Author(s):  
Alma Y. Galvez-Contreras ◽  
Rocio E. Gonzalez-Castaneda ◽  
Sonia Luquin ◽  
Oscar Gonzalez-Perez
Keyword(s):  
Stem Cells ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Growth Factor Receptors ◽  
Fibroblast Growth ◽  
Fibroblast Growth Factor Receptors

Growth factors, stem cells, and stroke

2008 ◽  
Vol 24 (3-4) ◽  
pp. E14 ◽  
Author(s):  
Haviryaji S. G. Kalluri ◽  
Robert J. Dempsey
Keyword(s):  
Stem Cells ◽  
Growth Factors ◽  
Growth Factor ◽  
Neural Stem Cells ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Compensatory Mechanism ◽  
Ischemic Tissue ◽  
And Migration

✓ Postischemic neurogenesis has been identified as a compensatory mechanism to repair the damaged brain after stroke. Several factors are released by the ischemic tissue that are responsible for proliferation, differentiation, and migration of neural stem cells. An understanding of their roles may allow future therapies based on treatment with such factors. Although damaged cells release a variety of factors, some of them are stimulatory whereas some are inhibitory for neurogenesis. It is interesting to note that factors like insulin-like growth factor–I can induce proliferation in the presence of fibroblast growth factor–2 (FGF-2), and promote differentiation in the absence of FGF-2. Meanwhile, factors like transforming growth factor–β can induce the differentiation of neurons while inhibiting the proliferation of neural stem cells. Therefore, understanding the role of each factor in the process of neurogenesis will help physicians to enhance the endogenous response and improve the clinical outcome after stroke. In this article the authors discuss the role of growth factors and stem cells following stroke.

Ghrelin promotes midbrain neural stem cells differentiation to dopaminergic neurons through Wnt/β‐catenin pathway

2020 ◽  
Vol 235 (11) ◽  
pp. 8558-8570 ◽  
Author(s):  
Bing Gong ◽  
Lingling Jiao ◽  
Xixun Du ◽  
Yong Li ◽  
Mingxia Bi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Dopaminergic Neurons

(+)-Cholesten-3-one induces differentiation of neural stem cells into dopaminergic neurons through BMP signaling

2010 ◽  
Vol 68 (3) ◽  
pp. 176-184 ◽  
Author(s):  
Dong-Feng Chen ◽  
Ling-Jie Meng ◽  
Shao-Hui Du ◽  
Hai-Ling Zhang ◽  
Hui Li ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Dopaminergic Neurons ◽  
Bmp Signaling

Tissue regeneration and repair in multiple sclerosis: the role of neural stem cells

2011 ◽  
pp. 60-66
Author(s):  
Stefano Pluchino ◽  
Roberto Furlan ◽  
Luca Muzio ◽  
Gianvito Martino
Keyword(s):  
Multiple Sclerosis ◽  
Stem Cells ◽  
Neural Stem Cells ◽  
Tissue Regeneration
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