scholarly journals Treatment of Distal Radius Bone Defects with Injectable Calcium Sulphate Cement

Bone Grafting ◽  
10.5772/30445 ◽  
2012 ◽  
Author(s):  
Deng Lei ◽  
Ma Zhanzhong ◽  
Yang Huaikuo ◽  
Xue Lei ◽  
Yang Gongbo
Keyword(s):  
Distal Radius ◽  
Calcium Sulphate ◽  
Bone Defects

Osseous integration of bovine hydroxyapatite ceramic in metaphyseal bone defects of the distal radius

2000 ◽  
Vol 25 (5) ◽  
pp. 833-841 ◽  
Author(s):  
Klaus-Dieter Werber ◽  
Robert B. Brauer ◽  
Wolfgang Weiß ◽  
Karen Becker
Keyword(s):  
Distal Radius ◽  
Bone Defects ◽  
Hydroxyapatite Ceramic ◽  
Osseous Integration ◽  
Bovine Hydroxyapatite ◽  
Metaphyseal Bone

scholarly journals Sinus Lift Augmentation by Using Calcium Sulphate. A Retrospective 12 Months Radiographic Evaluation Over 25 Treated Italian Patients

2015 ◽  
Vol 9 (1) ◽  
pp. 414-419 ◽  
Author(s):  
L. Laino ◽  
G. Troiano ◽  
G. Giannatempo ◽  
U. Graziani ◽  
D. Ciavarella ◽  
...  
Keyword(s):  
Bone Substitutes ◽  
Calcium Sulphate ◽  
Bone Defects ◽  
Bone Volume ◽  
Radiographic Evaluation ◽  
Sinus Lift ◽  
Valid Instrument ◽  
Tooth Extractions ◽  
Large Bone

Purpose : The aim of this investigation was to assess bone healing of sinus lift procedure in which the augmentation has been performed by using calcium sulphate like bone substitutes. The methods of this investigation how the use of Cone Beam Computed Tomography (CBCT) may be a valid instrument to support reconstructive surgery of the jaws. Patients and Methodology: 25 Patients presented large bone defects after tooth extractions located in the upper jaw posterior area. Vertical bone volume was assessed by CBCT examinations before and about six months after sinus lift surgery. Results: Examined defects treated with sinus lift surgery and evaluated by CBCT showed a strong increasing on the bone volume at 6 months follow up control. Conclusion: Calcium sulphate application in sinus lift surgery represent a safe and predictable option in the place of autologous bone. Therefore the application of CBCT investigation may give the clinicians the opportunity of evaluating with high precision value, the consistence of the bone defects before the surgery.

scholarly journals In VivoOsteogenesis of Vancomycin Loaded Nanohydroxyapatite/Collagen/Calcium Sulfate Composite for Treating Infectious Bone Defect Induced by Chronic Osteomyelitis

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaojie Lian ◽  
Kezheng Mao ◽  
Xi Liu ◽  
Xiumei Wang ◽  
Fuzhai Cui
Keyword(s):  
Bone Graft ◽  
Bone Defect ◽  
Calcium Sulfate ◽  
Chronic Osteomyelitis ◽  
Rabbit Model ◽  
Calcium Sulphate ◽  
Bone Defects ◽  
Bone Graft Substitute ◽  
Calcium Sulphate Hemihydrate

A novel antibacterial bone graft substitute was developed to repair bone defects and to inhibit related infections simultaneously. This bone composite was prepared by introducing vancomycin (VCM) to nanohydroxyapatite/collagen/calcium sulphate hemihydrate (nHAC/CSH). XRD, SEM, and CCK-8 tests were used to characterize the structure and morphology and to investigate the adhesion and proliferation of murine osteoblastic MC3T3-E1 cell on VCM/nHAC/CSH composite. The effectiveness in restoring infectious bone defects was evaluatedin vivousing a rabbit model of chronic osteomyelitis. Ourin vivoresults implied that the VCM/nHAC/CSH composite performed well both in antibacterial ability and in bone regeneration. This novel bone graft substitute should be very promising for the treatment of bone defect-related infection in orthopedic surgeries.

scholarly journals Treatment of Cavitary Bone Defects in Chronic Osteomyelitis: Bioactive glass S53P4 vs. Calcium Sulphate Antibiotic Beads

2017 ◽  
Vol 2 (4) ◽  
pp. 194-201 ◽  
Author(s):  
Albert Ferrando ◽  
Joan Part ◽  
Jose Baeza
Keyword(s):  
Postoperative Complications ◽  
Hospital Stay ◽  
Chronic Osteomyelitis ◽  
Average Length ◽  
Length Of Hospital Stay ◽  
Calcium Sulphate ◽  
Bone Defects ◽  
Group 2 ◽  
Group 1

Abstract. Aim: To evaluate the efficacy of bioglass (BAG-S53P4) in the treatment of patients with chronic osteomyelitis and compare the results with calcium sulphate antibiotic beads in one medical centre.Methods: Retrospective analysis of 25 cases. Inclusion criteria: patients diagnosed clinically and radiographically of osteomyelitis and treated surgically (Group 1: cavitary bone defects treated with bioglass and Group 2: cavitary bone defects treated with calcium sulphate antibiotic beads) during the period of 2014 and 2015 in one medical centre.Results: Patients in group 1 (bioglass treatment): total of 12 patients (11 males and 1 female) with mean age: 50 years (30-86). Average length of hospital stay was 22 days and mean follow-up time: 23 months (16-33). Mean erythrocyte sedimentation rate (ESR) and mean c-reactive protein (CRP) before surgery: 55mm/hr and 54 mg/L, respectively. Mean ESR and mean CRP in last blood exam: 18 mm/hr and 8 mg/L, respectively. There were 2 postoperative complications: seroma formation and delayed wound healing. Only 1 patient had recurrence of infection.Patients in group 2 (calcium sulphate antibiotic beads treatment): total of 13 patients (9 males and 4 females) with mean age: 48 years (17-67). Average length of hospital stay was 21 days and mean follow-up time 22 months (16-29). Mean ESR and mean CRP before surgery: 51mm/hr and 41 mg/L, respectively. Mean ESR and mean CRP in last blood test: 15 mm/hr and 11 mg/L. 2 postoperative complications were registered: chronic expanding hematoma of the muscle flap donor site and seroma formation. 1 patient had recurrence of infection. Overall, there were no differences in recurrence of infection, p=0.740 and in complication rate, p=0.672. 11 (91,7%) patients in group 1 and 12 (92,3%) patients in group 2 showed no signs of recurrence of infection both clinically and radiologically at final follow-up.The most frequent cause of osteomyelitis in group 1 was post traumatic while a postsurgical aetiology was more frequent in group 2. The distal tibia was the most common location. The most frequent pathogen isolated in both groups was methicillin sensible staphylococcus aureus.Conclusions: An advance in treatment of patients with cavitary bone defects in chronic osteomyelitis is the use of synthetic bone substitutes although current evidence is low. In this study, we demonstrate how bioglass without local antibiotics and calcium sulphate antibiotic beads are both equally effective treatment options. Overall, there were no differences between groups in mean hospital stay, complication rates and recurrence of infection.

Indentation Testing of a Bone Defect Filled with Two Different Injectable Bone Substitutes

2005 ◽  
Vol 284-286 ◽  
pp. 89-92 ◽  
Author(s):  
Jian Sheng Wang ◽  
K.E. Tanner ◽  
Saba Abdulghani ◽  
Lars Lidgren
Keyword(s):  
Calcium Phosphate ◽  
Mechanical Loading ◽  
Bone Substitutes ◽  
Calcium Sulphate ◽  
Bone Defects ◽  
Indentation Load ◽  
Indentation Testing ◽  
Significant Difference ◽  
Bone Integration ◽  
And Control

Injectable bone substitutes (IBS) based on calcium phosphate (CaP) and/or calcium sulphate (CaS) are used as fillers in bone defects to stimulate bone integration and allow mechanical loading. Two types of IBS, IBS-1 is CaP+20%CaS and IBS-2 is CaS+40% hydroxyapatite, were investigated. The materials were injected into holes in the femur and tibia in rabbits. After 10 weeks the femora were subjected to indentation testing and tibiae were prepared for histology evaluation. IBS-1 lead to an higher indentation load compared to control, that is no material inserted, while IBS-2 showed no significant difference between material and control. Histology showed that with IBS-1, the bone penetrated into and integrated with the material in the defect. With IBS-2, new bone grew into the outer 0.5-1.0 mm. The materials could be used for different indications, such as to support fracture healing or in contained cavities.

scholarly journals Early Results of the Study of Reparative Peculiarities of Various Osteoplastic Materials in Experimental Bone Defects

2017 ◽  
pp. 40-47
Author(s):  
K. A. Egiazaryan ◽  
G. D. Lazishvili ◽  
K. I. Akmataliev ◽  
A. P. Ettinger ◽  
A. P. Rat’Ev ◽  
...  
Keyword(s):  
Bone Cement ◽  
Bone Tissue ◽  
Tricalcium Phosphate ◽  
Calcium Sulphate ◽  
Bone Defects ◽  
Spongy Bone ◽  
Early Results ◽  
Calcium Phosphate Bone Cement ◽  
Bone Trabeculae ◽  
Osteoplastic Material

Purpose. To determine the optimum osteoplastic material for activation of reparative osteogenesis and substitution of traumatic defects in metaepiphyseal spongy bone tissue.Material and methods.Comparative experimental morphological study was performed on 12 matured male Chinchilla rabbits with body weight 2500-2800g. A model of critical defects of spongy bone tissue was used. Bone defects were filled with 3 types of osteoplastic material: composite calcium sulphate bone cement; xenogenous hydroxyapatite-based material with granulated paste of synthetic peptides (P-15); β-tricalcium phosphate-based material with gauging liquid (calcium phosphate bone cement).Results.Implantation of calcium sulphate bone cement showed rapid osteogenesis stimulation at terms 1.5 months and reduction of newly formed bone tissue mass by 3rd month due to active resorption of the residual material. Implantation of hydroxyapatite-based material with P-15 resulted in osteogenesis stimulation on its surface however because of its mechanical instability and absence of active resorption of that material only a moderate formation of bone trabeculae was observed. At implantation of β-tricalcium phosphate-based material an active resorption of osteoplastic material, formation of trabecular system and its reorganization into trabecular network of femoral metaepiphyseal spongy bone accompanied by the formation of mature bone trabeculae was noted by month 3.Conclusion. Mechanical stability of osteoplastic material and subsequent gradual resorption as well as formation of mature bine trabeculae indicates the efficacy of β-tricalcium phosphate-based material.

scholarly journals Clinical use of calcium sulphate in bone regeneration therapy: Case report

2003 ◽  
Vol 50 (1) ◽  
pp. 24-28 ◽  
Author(s):  
Milan Radulovic ◽  
Bozidar Brkovic
Keyword(s):  
Case Report ◽  
Bone Regeneration ◽  
Oral Surgery ◽  
Calcium Sulphate ◽  
Bone Defects ◽  
Clinical Use ◽  
Alloplastic Material

It is well known that a variety of materials has been used to fill bone defects after oral surgery procedures. In this study, we showed 2 patients with large osseus defects after oral surgery procedures which were filled with calcium sulphate. The use of this alloplastic material should indicate on effective bone regeneration therapy.

scholarly journals Early Results of the Study of Reparative Peculiarities of Various Osteoplastic Materials in Experimental Bone Defects

2017 ◽  
Vol 24 (2) ◽  
pp. 40-47
Author(s):  
K. A Egiazaryan ◽  
G. D Lazishvili ◽  
K. I Akmataliev ◽  
A. P Ettinger ◽  
A. P Rat’ev ◽  
...  
Keyword(s):  
Bone Cement ◽  
Bone Tissue ◽  
Tricalcium Phosphate ◽  
Calcium Sulphate ◽  
Bone Defects ◽  
Spongy Bone ◽  
Early Results ◽  
Calcium Phosphate Bone Cement ◽  
Bone Trabeculae ◽  
Osteoplastic Material

Purpose. To determine the optimum osteoplastic material for activation of reparative osteogenesis and substitution of traumatic defects in metaepiphyseal spongy bone tissue. Material and methods. Comparative experimental morphological study was performed on 12 matured male Chinchilla rabbits with body weight 2500-2800g. A model of critical defects of spongy bone tissue was used. Bone defects were filled with 3 types of osteoplastic material: composite calcium sulphate bone cement; xenogenous hydroxyapatite-based material with granulated paste of synthetic peptides (P-15); β-tricalcium phosphate-based material with gauging liquid (calcium phosphate bone cement). Results. Implantation of calcium sulphate bone cement showed rapid osteogenesis stimulation at terms 1.5 months and reduction of newly formed bone tissue mass by 3rd month due to active resorption of the residual material. Implantation of hydroxyapatite-based material with P-15 resulted in osteogenesis stimulation on its surface however because of its mechanical instability and absence of active resorption of that material only a moderate formation of bone trabeculae was observed. At implantation of β-tricalcium phosphate-based material an active resorption of osteoplastic material, formation of trabecular system and its reorganization into trabecular network of femoral metaepiphyseal spongy bone accompanied by the formation of mature bone trabeculae was noted by month 3. Conclusion. Mechanical stability of osteoplastic material and subsequent gradual resorption as well as formation of mature bine trabeculae indicates the efficacy of β-tricalcium phosphate-based material.

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