scholarly journals NVS and Staphylococci in the Oral Cavity – A Cause of Infective Endocarditis

Endocarditis ◽  
10.5772/29960 ◽  
2012 ◽  
Author(s):  
Yuko Ohara-Nemoto ◽  
Shigenobu Kimura ◽  
Takayuki K.
Keyword(s):  
Infective Endocarditis ◽  
Oral Cavity

scholarly journals Draft Genome Sequence of a Cardiobacterium hominis Strain Isolated from Blood Cultures of a Patient with Infective Endocarditis

2016 ◽  
Vol 4 (5) ◽  
Author(s):  
Florian Tagini ◽  
Trestan Pillonel ◽  
Sandra Asner ◽  
Guy Prod’hom ◽  
Gilbert Greub
Keyword(s):  
Infective Endocarditis ◽  
Oral Cavity ◽  
Genome Sequence ◽  
Draft Genome ◽  
Blood Cultures ◽  
Pathogenic Strain ◽  
Infectious Endocarditis ◽  
Draft Genome Sequence ◽  
Commensal Bacterium

Cardiobacterium hominis is a well-known commensal bacterium of the oral cavity and an agent of infective endocarditis in humans. Here, we provide a draft genome sequence of a pathogenic strain isolated from blood cultures of a patient with infectious endocarditis.

scholarly journals Complete Genome Sequence of Streptococcus oralis SF100, Isolated from Blood Cultures from a Patient with Infective Endocarditis

2021 ◽  
Vol 10 (28) ◽  
Author(s):  
Ji Hee Lee ◽  
Hyun Jung Ji ◽  
Ho Seong Seo ◽  
Paul M. Sullam
Keyword(s):  
Infective Endocarditis ◽  
Animal Models ◽  
Oral Cavity ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Blood Cultures ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Content Type ◽  
Streptococcus Oralis

Streptococcus oralis is a commensal viridans group streptococcus of the human oral cavity and a frequent cause of endovascular infection. Here, we report the complete whole-genome sequence of S. oralis strain SF100, which was originally isolated from the blood of a patient with infective endocarditis. This strain contains the lysogenic bacteriophage SM1, which enhances the virulence of SF100 in animal models of endocardial infection.

scholarly journals Isolation and characterization of Streptococcus mutans in heart valve and dental plaque specimens from a patient with infective endocarditis

2006 ◽  
Vol 55 (8) ◽  
pp. 1135-1140 ◽  
Author(s):  
Ryota Nomura ◽  
Kazuhiko Nakano ◽  
Hirotoshi Nemoto ◽  
Kazuyo Fujita ◽  
Satoko Inagaki ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Dental Caries ◽  
Oral Cavity ◽  
Streptococcus Mutans ◽  
Heart Valve ◽  
Dental Plaque ◽  
Biochemical Properties ◽  
Oral Streptococci ◽  
Isolation And Characterization

Streptococcus mutans, known to be an aetiologic agent of dental caries, also causes infective endocarditis (IE), although a comparison of isolates from the oral cavity and infected heart valve of the same patient has not been reported. In the present study, infected heart valve and dental plaque samples from a patient with IE were analysed. Broad-range PCR with DNA sequencing revealed that 50 clones from the dental plaque isolates were composed of oral streptococci and periodontopathic bacteria, whereas only Streptococcus mutans was detected in 50 clones from the heart valve. Eighteen strains of Streptococcus mutans were isolated from dental plaque and seven from the heart valve, and the biochemical properties of each were in accordance with those of Streptococcus mutans. DNA fingerprinting analysis revealed that all the oral isolates of Streptococcus mutans had similar patterns, which were different from those of the isolates from the infected heart valve. Western blotting using glucosyltransferase (GTF)-specific antiserum showed that the seven strains from the heart valve lacked the three types of intact GTF. In addition, the sucrose-dependent adhesion rates of these isolates were significantly lower than those of the oral isolates (P<0.001). Furthermore, the isolates from the heart valve were less susceptible to erythromycin and kanamycin. These results indicate that the properties of the Streptococcus mutans strains isolated from the infected valve were different from those of typical oral strains, which may be related to the effects of IE.

scholarly journals Relationship between 18F-FDG Uptake in the Oral Cavity, Recent Dental Treatments, and Oral Inflammation or Infection: A Retrospective Study of Patients with Suspected Endocarditis

Diagnostics ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 625
Author(s):  
Geertruida W. Dijkstra ◽  
Andor W. J. M. Glaudemans ◽  
Paola A. Erba ◽  
Marjan Wouthuyzen-Bakker ◽  
Bhanu Sinha ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Oral Health ◽  
Infective Endocarditis ◽  
Oral Cavity ◽  
Fdg Pet ◽  
Oral Health Status ◽  
Pet Ct ◽  
Oral Inflammation ◽  
18F Fdg ◽  
Fdg Pet Ct

[18F]-fluorodeoxyglucose positron emission tomography ([18F]FDG PET/CT) has proven to be a useful diagnostic tool in patients with suspected infective endocarditis (IE), but is conflicting in relation to dental procedures. Questions: Is there a correlation between [18F]FDG PET/CT findings, recent dental treatment, and an affected oral cavity? (2) Is there a correlation between infective endocarditis (IE), oral health status, and (extra)cardiac findings on [18F]FDG PET/CT? Methods: This retrospective study included 52 patients. All [18F]FDG PET/CT scans were examined visually by pattern recognition using a three-point scale and semi-quantified within the volume of interest (VOI) using SUVmax. Results: 19 patients were diagnosed with IE (group 1), 14 with possible IE (group 2), and 19 without IE based on the modified Duke criteria (group 3). No correlation was found between visual PET and SUVmax and sites of oral inflammation and infection. The visual PET scores and SUVmax were not significantly different between all groups. A significant difference in the SUVmax of the valve between all groups was observed. Conclusions: This study suggests that no correlation exists between the PET findings in the oral cavity and dental treatments or inflammation/infection. No correlation between IE, actual oral health status, and extra-cardiac findings was demonstrated. Additional research is needed to conclude whether [18F]FDG PET/CT imaging is a reliable diagnostic modality for oral inflammation and infection sites.

scholarly journals Prevention of infective endocarditis in dental procedures for tetralogy of fallot patients

2021 ◽  
Vol 5 (2) ◽  
pp. 66
Author(s):  
Ari Rosita Irmawati ◽  
Ayulistya Paramita Sutarto
Keyword(s):  
Infective Endocarditis ◽  
Oral Cavity ◽  
Tetralogy Of Fallot ◽  
Dental Treatment ◽  
Treatment Plan ◽  
Pediatric Dentistry ◽  
Prophylactic Antibiotics ◽  
Corrective Surgery ◽  
Pulp Chamber ◽  
Dental Procedures

Objectives: Tetralogy of Fallot (ToF) is a congenital heart defect that is often found in children. Complication that can occur is infective endocarditis caused by bacteria that are often found in the oral cavity. Children with ToF are in a high risk of caries, especially in primary dentition. Preparation of the oral cavity must be done before the cardiac surgery. A proper examination and diagnosis of caries is required in determining the dental treatment to reduce the risk of infective endocarditis. Case Report: A boy aged 4 years, weighing 20 kg came to the pediatric dentistry clinic in Surabaya on a referral from Kediri. The patient had ToF with high caries index and will undergo cardiac corrective surgery. Through a brief anamnesis, it was found that this patient's fingernails and lips easily turn blue (cyanosis) if the patient is in an anxious condition. The panoramic photo shows teeth 51, 52, 54, 61, 62, 74, 84 showing radiolucent images from the enamel to the pulp chamber. Conclusion: Prophylactic antibiotics should be given to ToF patients before procedures involving the gingiva and pulp. Radiographs are needed to help establish the diagnosis and plan treatment. Proper oral and dental care must be taken to prevent the occurrence of infective endocarditis. Errors in determining the diagnosis can lead to errors in the treatment plan and increase the risk of infective endocarditis.

scholarly journals Infective Endocarditis Caused by Granulicatella elegans Originating in the Oral Cavity

2005 ◽  
Vol 43 (3) ◽  
pp. 1405-1407 ◽  
Author(s):  
Y. Ohara-Nemoto ◽  
K. Kishi ◽  
M. Satho ◽  
S. Tajika ◽  
M. Sasaki ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Oral Cavity

scholarly journals Streptococcus gordonii: A Rare Cause of Infective Endocarditis

2019 ◽  
Vol 2019 ◽  
pp. 1-2 ◽  
Author(s):  
Natalia Mosailova ◽  
Justina Truong ◽  
Tyson Dietrich ◽  
John Ashurst
Keyword(s):  
Infective Endocarditis ◽  
Oral Cavity ◽  
Antibiotic Prophylaxis ◽  
Streptococcus Gordonii ◽  
Invasive Procedures ◽  
Dental Abscess ◽  
Dental Procedures ◽  
Life Threatening

Infective endocarditis is a rare but life-threatening disease seen across the globe. Organisms from the oral cavity still represent a large proportion of pathogens seen in endocarditis and can be from either daily dental routines or invasive procedures. With the recent changes to antibiotic prophylaxis for infective endocarditis prior to dental procedures, the physician must have a heightened degree of suspicion when presented with a patient with undifferenced sepsis following dental procedures. The authors present a case of infective endocarditis caused by Streptococcus gordonii after the drainage of a dental abscess.

scholarly journals Infective endocarditis today

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 2188 ◽  
Author(s):  
Donato D'Agostino
Keyword(s):  
Infectious Disease ◽  
Infective Endocarditis ◽  
Literature Review ◽  
Oral Cavity ◽  
Antibiotic Therapy ◽  
Organ Failure ◽  
Clinical Experience ◽  
Cardiac Valves ◽  
Multi Organ Failure

Endocarditis is an infectious disease caused by numerous microorganisms, many of which habitually colonize the oral cavity and skin. Various bacteria and bacterial factors influence the duration of bacteremia and the possible colonization of cardiac valves. If not recognized and treated early, the disease may have serious consequences until death: despite the possibility of setting up targeted antibiotic therapy, it may occur in 30% of cases. This event is related to sepsis that develops in these patients and can result in cellular functional alterations in many districts, resulting in multi-organ failure (MOF) status. This paper is aimed to present an overview of this condition, based on the author’s own clinical experience and literature review.

scholarly journals Molecular recognition of sialoglycans by streptococcal Siglec-like adhesins: toward the shape of specific inhibitors

2021 ◽  
Author(s):  
Cristina Di Carluccio ◽  
Alba Silipo ◽  
Roberta Marchetti ◽  
Barbara Ben ◽  
Koichi Fukase ◽  
...  
Keyword(s):  
Sialic Acid ◽  
Infective Endocarditis ◽  
Molecular Recognition ◽  
Oral Cavity ◽  
Commensal Bacteria ◽  
Streptococcus Gordonii ◽  
Healthy Individuals ◽  
Sialic Acid Binding ◽  
Specific Inhibitors

Streptococcus gordonii and sanguinis, commensal bacteria present in the oral cavity of healthy individuals, upon entry into the bloodstream can become pathogenic, causing infective endocarditis (IE). Sialic acid-binding serine-rich repeat...

Oral and Oropharyngeal Sensory Function in Adults With Chronic Obstructive Pulmonary Disease

2020 ◽  
Vol 29 (2) ◽  
pp. 864-872
Author(s):  
Fernanda Borowsky da Rosa ◽  
Adriane Schmidt Pasqualoto ◽  
Catriona M. Steele ◽  
Renata Mancopes
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Oral Cavity ◽  
Pulmonary Disease ◽  
Thermal Sensation ◽  
Sensory Function ◽  
Control Group ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Age Related ◽  
Copd Patients

Introduction The oral cavity and pharynx have a rich sensory system composed of specialized receptors. The integrity of oropharyngeal sensation is thought to be fundamental for safe and efficient swallowing. Chronic obstructive pulmonary disease (COPD) patients are at risk for oropharyngeal sensory impairment due to frequent use of inhaled medications and comorbidities including gastroesophageal reflux disease. Objective This study aimed to describe and compare oral and oropharyngeal sensory function measured using noninstrumental clinical methods in adults with COPD and healthy controls. Method Participants included 27 adults (18 men, nine women) with a diagnosis of COPD and a mean age of 66.56 years ( SD = 8.68). The control group comprised 11 healthy adults (five men, six women) with a mean age of 60.09 years ( SD = 11.57). Spirometry measures confirmed reduced functional expiratory volumes (% predicted) in the COPD patients compared to the control participants. All participants completed a case history interview and underwent clinical evaluation of oral and oropharyngeal sensation by a speech-language pathologist. The sensory evaluation explored the detection of tactile and temperature stimuli delivered by cotton swab to six locations in the oral cavity and two in the oropharynx as well as identification of the taste of stimuli administered in 5-ml boluses to the mouth. Analyses explored the frequencies of accurate responses regarding stimulus location, temperature and taste between groups, and between age groups (“≤ 65 years” and “> 65 years”) within the COPD cohort. Results We found significantly higher frequencies of reported use of inhaled medications ( p < .001) and xerostomia ( p = .003) in the COPD cohort. Oral cavity thermal sensation ( p = .009) was reduced in the COPD participants, and a significant age-related decline in gustatory sensation was found in the COPD group ( p = .018). Conclusion This study found that most of the measures of oral and oropharyngeal sensation remained intact in the COPD group. Oral thermal sensation was impaired in individuals with COPD, and reduced gustatory sensation was observed in the older COPD participants. Possible links between these results and the use of inhaled medication by individuals with COPD are discussed.

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