scholarly journals Abuse in Childhood and HPA Axis Functioning in Mentally Ill Patients

10.5772/29368 ◽  
2012 ◽  
Author(s):  
Spila Bozena ◽  
Urbanska A
Keyword(s):  
Hpa Axis ◽  
Mentally Ill ◽  
Hpa Axis Functioning

Attachment style and salivary cortisol awakening response in eating disorders

2016 ◽  
Vol 33 (S1) ◽  
pp. S162-S162
Author(s):  
F. De Riso ◽  
R. Giugliano ◽  
A.M. Monteleone ◽  
M. Nigro ◽  
F. Pellegrino ◽  
...  
Keyword(s):  
Eating Disorders ◽  
Attachment Style ◽  
Hpa Axis ◽  
Adult Attachment ◽  
Attachment Styles ◽  
Cortisol Awakening Response ◽  
Anxious Attachment ◽  
Significant Difference ◽  
Anxious Group ◽  
Hpa Axis Functioning

IntroductionEarly life experiences can influence hypotalamus-pituitary-adrenal (HPA) axis regulation and adult attachment styles. Furthermore, several studies showed that in patients with eating disorders (EDs) there is a prevalence of insecure attachment. However, the relationship between adult attachment style, HPA axis functioning and onset of EDs is largely unknown.Objectives and aimsIn order to evaluate possible associations between attachment styles and HPA axis functioning in EDs, we investigated Cortisol Awakening Response (CAR) in ED patients with different attachment styles.MethodsTwenty adult patients with EDs were classified in three groups, according to the Experience in Close Relationship questionnaire (6 with secure attachment, 6 with anxious attachment and 8 with avoidant attachment). Saliva samples were collected at awakening and 15, 30 and 60 minutes after.ResultsThere was a significant difference among the groups in both awakening and post-awakening cortisol concentrations. In particular, compared to secure and avoidant groups, the anxious group exhibited lower cortisol concentrations at awakening and post-awakening with a preservation of the timing of the CAR.DiscussionPresent findings demonstrate that anxious attachment style is linked to flattened CAR in EDs. This pattern has been associated with other psychiatric disorders. Therefore, attachment style could influence the HPA functioning and it could play, although not specifically, a role in pathophysiology of EDs.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Maternal depression across the first years of life compromises child psychosocial adjustment; relations to child HPA-axis functioning

2016 ◽  
Vol 64 ◽  
pp. 47-56 ◽  
Author(s):  
Yael Apter-Levi ◽  
Maayan Pratt ◽  
Adam Vakart ◽  
Michal Feldman ◽  
Orna Zagoory-Sharon ◽  
...  
Keyword(s):  
Maternal Depression ◽  
Hpa Axis ◽  
Psychosocial Adjustment ◽  
Hpa Axis Functioning

scholarly journals Emotion Regulation Regulates More Than Emotion

2016 ◽  
Vol 5 (1) ◽  
pp. 37-51 ◽  
Author(s):  
Kirsten Gilbert ◽  
Susan Mineka ◽  
Richard E. Zinbarg ◽  
Michelle G. Craske ◽  
Emma K. Adam
Keyword(s):  
Emotion Regulation ◽  
Problem Solving ◽  
Hpa Axis ◽  
Emotional Expression ◽  
Internalizing Disorders ◽  
Cortisol Reactivity ◽  
History Of ◽  
Support Seeking ◽  
Regulation Strategies ◽  
Hpa Axis Functioning

Maladaptive emotion regulation and dysregulated hypothalamic-pituitary-adrenal (HPA) axis functioning are characteristic of depression and anxiety. However, little research examines whether and how emotion regulation affects HPA axis functioning. We utilized an experience sampling methodology to examine associations between three emotion regulation strategies (problem solving, disengagement, and emotional expression/support seeking) and diurnal cortisol rhythms and reactivity in everyday life. Participants were young adults with current, past, or no history of internalizing disorders (depression or anxiety; N = 182). Across participants, problem solving was associated with an elevated cortisol awakening response (CAR), whereas disengagement was associated with a steeper cortisol slope. Only for individuals with internalizing disorders was momentary problem solving and emotional expression/support seeking associated with higher cortisol reactivity and emotional expression/support seeking associated with a flatter diurnal slope and blunted CAR. Results provide insight into associations between emotion regulation and day-to-day HPA axis functioning.

scholarly journals Identifying pathways from early adversity to psychopathology: A review on dysregulated HPA axis functioning and impaired self-regulation in early childhood

2020 ◽  
Vol 17 (6) ◽  
pp. 808-827 ◽  
Author(s):  
Christiane Wesarg ◽  
Alithe L. Van Den Akker ◽  
Nicole Y. L. Oei ◽  
Machteld Hoeve ◽  
Reinout W. Wiers
Keyword(s):  
Early Childhood ◽  
Hpa Axis ◽  
Self Regulation ◽  
Early Adversity ◽  
Hpa Axis Functioning

Novel agents in development for the treatment of depression

CNS Spectrums ◽  
2013 ◽  
Vol 18 (s1) ◽  
pp. 34-41 ◽  
Author(s):  
Meghan M. Grady ◽  
Stephen M. Stahl
Keyword(s):  
Protein Synthesis ◽  
Hpa Axis ◽  
Therapeutic Efficacy ◽  
Novel Agents ◽  
The Novel ◽  
Glutamatergic Neurotransmission ◽  
Downstream Effects ◽  
Investigational Drugs ◽  
Treatment Of Depression ◽  
Hpa Axis Functioning

There are several investigational drugs in development for the treatment of depression. Some of the novel antidepressants in development target monoaminergic neurotransmission in accordance with the “monoamine hypothesis of depression.” However, the current conceptualization of antidepressant actions is that it is the downstream effects on protein synthesis and neuroplasticity that account for therapeutic efficacy, rather than the immediate effects on synaptic monoamine levels. Thus, a number of novel agents in development directly target components of this “neuroplasticity hypothesis of depression,” including hypothetically overactive glutamatergic neurotransmission and dysfunctional hypothalamic–pituitary–adrenal (HPA) axis functioning.

Worse than sticks and stones? Bullying is associated with altered HPA axis functioning and poorer health

2011 ◽  
Vol 77 (2) ◽  
pp. 183-190 ◽  
Author(s):  
Jennifer M. Knack ◽  
Lauri A. Jensen-Campbell ◽  
Andrew Baum
Keyword(s):  
Hpa Axis ◽  
Sticks And Stones ◽  
Hpa Axis Functioning

scholarly journals Differential associations between childhood trauma subtypes and adolescent HPA-axis functioning

2015 ◽  
Vol 54 ◽  
pp. 103-114 ◽  
Author(s):  
Kate R. Kuhlman ◽  
Elisa G. Geiss ◽  
Ivan Vargas ◽  
Nestor L. Lopez-Duran
Keyword(s):  
Childhood Trauma ◽  
Hpa Axis ◽  
Hpa Axis Functioning

scholarly journals Psychological and Environmental Correlates of HPA Axis Functioning in Parentally Bereaved Children: Preliminary Findings

2013 ◽  
Vol 26 (2) ◽  
pp. 233-240 ◽  
Author(s):  
Julie B. Kaplow ◽  
Danielle N. Shapiro ◽  
Britney M. Wardecker ◽  
Kathryn H. Howell ◽  
James L. Abelson ◽  
...  
Keyword(s):  
Hpa Axis ◽  
Environmental Correlates ◽  
Parentally Bereaved ◽  
Bereaved Children ◽  
Hpa Axis Functioning ◽  
Parentally Bereaved Children
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