scholarly journals Encephalopathy Associated with Psychotropic Drug Therapy

Author(s):  
Yuji Odagaki
2012 ◽  
Vol 24 (4) ◽  
pp. 247-250
Author(s):  
József Simkó ◽  
Gabriella Nagy ◽  
Anikó Dózsa ◽  
István Lörincz

Background: Although sinus node dysfunction is primarily related to degenerative fibrosis of nodal tissue in the elderly, it may occur at any age secondary to other cardiac abnormalities or extrinsic causes. Pharmacologic agents including psychotropic drug therapy may also play a role.Method: We present the case of a 53-year-old woman with bipolar affective disorder in whom antipsychotic agents were suspected of inducing sinus node dysfunction.Result: The combination of psychotropic agents including lithium, quetiapine and carbamazepine (first occasion) or escitalopram (second occasion) has been implicated as a cause for sinus node dysfunction.Conclusion: Patients with severe mental illness usually require long-term psychotropic drug therapy, often in combination. This may enhance efficacy but also involves an increased risk of adverse effects including cardiotoxicity.


1993 ◽  
Vol 5 (1) ◽  
pp. 33-48 ◽  
Author(s):  
Ingmar Skoog ◽  
Lars Nilsson ◽  
Sten Landahl ◽  
Bertil Steen

The prevalence of mental disorders was studied in a representative sample of 85-year-old living in Gothenburg, Sweden, (n=494). All subjects were examined by a psychiatrist, whose diagnoses were defined according to the DSM-III-R criteria. In the sample, the prevalence of dementia was 29.8%, and of any other mental disorder was 24.3%. Psychotic disorders were present in 4.7%, depressive disorders in 12.6%, and anxiety disorders in 10.5%. Anxiety disorders were more common in women than in men. Of all subjects, 42.5% used a psychotropic drug (men 30.1%, women 47.6%, p<0.001), 34.2% used anxiolytic-sedatives, 14.0% used antidepressants, and 5.7% used neuroleptics. Women used significantly more anxiolytic-sedatives and antidepressants than did men. Of those with no mental disorders, 29.1% used a psychotropic drug. Although the prescription of psychotropic drugs was high, only one fifth of those with depressive disorders received antidepressant drug therapy and one tenth of those with psychotic disorders received neuroleptics.


1974 ◽  
Vol 2 (3) ◽  
pp. 129-134 ◽  
Author(s):  
Elina Hemminki

The use of psychotropic drugs is on the increase. The purpose of this study was to analyse the information provided by patients themselves with regard to the nature of the diseases and the symptoms for which psychotropic drugs are prescribed. The subjects ( N=307) for the study were chosen from among people visiting a pharmacy. The cases were consecutively picked up of customers receiving psychotropic drugs by prescription; the control group comprised the next-following customers to buy some other prescribed drug. Comparison of the two groups suggested that the reasons for the increased use of drugs should be traced back to the doctor and the factors that influence him. It seems that one mechanism to which the increased utilization of psychotropic drugs is attributable arises from the broadened field of indications.


Sign in / Sign up

Export Citation Format

Share Document