scholarly journals Genetic Factors Influencing the Risk and Clinical Outcome of Neuroblastoma

Author(s):  
Diana T. ◽  
Lesley J.
2017 ◽  
Vol 24 (10) ◽  
pp. 969-978 ◽  
Author(s):  
Peggy M. Kostakou ◽  
George Hatzigeorgiou ◽  
Vana Kolovou ◽  
Sophie Mavrogeni ◽  
Genovefa D. Kolovou

2019 ◽  
Vol 29 ◽  
pp. S798
Author(s):  
Till Andlauer ◽  
Thomas Mühleisen ◽  
Felix Hoffstaedter ◽  
Alexander Teumer ◽  
Anja Teuber ◽  
...  

2002 ◽  
Vol 13 (11) ◽  
pp. 614-618 ◽  
Author(s):  
Christina K. Haston ◽  
Mary Corey ◽  
Lap-Chee Tsui

2013 ◽  
Vol 31 (6) ◽  
pp. 708-716 ◽  
Author(s):  
Andrew May ◽  
John M. Pettifor ◽  
Shane A. Norris ◽  
Michèle Ramsay ◽  
Zané Lombard

Crop Science ◽  
2001 ◽  
Vol 41 (1) ◽  
pp. 51-56 ◽  
Author(s):  
Yolanda López ◽  
Olin D. Smith ◽  
Scott A. Senseman ◽  
William L. Rooney

2019 ◽  
Vol 85 (10) ◽  
pp. S128
Author(s):  
Josephine Mollon ◽  
Emma Knowles ◽  
Samuel Mathais ◽  
Amanda Rodrigue ◽  
Marinka Koenis ◽  
...  

2019 ◽  
Vol 53 (04) ◽  
pp. 155-161 ◽  
Author(s):  
Daniel J. Müller ◽  
Zoe Rizhanovsky

AbstractPharmacogenetics is the division of science addressing how genetic factors contribute to the metabolism, response, and side effects of a given medication. What was once regarded as a subdivision of genetics and pharmacology is now recognized as its own field and has its own unique story of origin. While the term “pharmacogenetics” was coined by Friedrich Vogel in 1959, the relevance of inherited genetic traits in affecting the clinical outcome to xenobiotics has been observed long before. In fact, there is much hope that pharmacogenetics can help unravel the “mysteries” as to why different people may display variable responses to the same medication as well as identify new drug targets. This article will highlight the conceptual framework for pharmacogenetics advanced by pioneer scientists Arno Motulsky and Friedrich Vogel (both human geneticists), as well as Werner Kalow (clinical pharmacologist), leading up to the creation of modern pharmacogenetics. Finally, the practical implications and first steps toward implementation for current psychiatric treatment are reviewed followed by an outlook on future studies.


2000 ◽  
Vol 19 (1) ◽  
pp. 89-99 ◽  
Author(s):  
Jay Joseph

Mental health textbooks sometimes provide inaccurate information, typically supporting common beliefs in the field. Psychiatry and psychology textbooks' discussion of the schizophrenia adoption studies is examined. Particular attention is paid to the earlier studies, which helped pave the way for the current widespread acceptance of the importance of genetic factors influencing psychological trait differences. This article compares the accounts of 30 textbooks to the original studies they reviewed. Generally, problems with these textbooks' accounts include (1) the failure to critically assess the original researchers' methods and conclusions, (2) some textbooks' reliance on secondary sources, (3) the failure to discuss published critiques of the schizophrenia adoption studies, (4) inaccuracy in reporting the original findings, (5) the claim that studies finding nonsignificant results support the genetic position, and (6) a failure to discuss the potentially invalidating environmental confounds in the schizophrenia adoption studies (through the selective placement of adoptees). It is concluded that, in general, these textbooks have served to rubber-stamp mainstream psychiatry's questionable claims about the schizophrenia adoption studies at the expense of a thorough critical analysis.


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