scholarly journals Periodontal Disease and Carotid Atherosclerosis: Mechanisms of the Association

10.5772/27514 ◽  
2012 ◽  
Author(s):  
Maria Serena De Franceschi ◽  
Leonzio Fortunato ◽  
Claudio Carallo ◽  
Cesare Tripolino ◽  
Concetta Irace ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Carotid Atherosclerosis

Periodontal disease and carotid atherosclerosis: A meta-analysis of 17,330 participants

2016 ◽  
Vol 203 ◽  
pp. 1044-1051 ◽  
Author(s):  
Xian-Tao Zeng ◽  
Wei-Dong Leng ◽  
Yat-Yin Lam ◽  
Bryan P. Yan ◽  
Xue-Mei Wei ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Carotid Atherosclerosis ◽  
Meta Analysis

scholarly journals BIOCHEMICAL AND CLINICAL EVALUATION OF CORRELATION OF PERIODONTITIS AND EARLY CAROTID ATHEROSCLEROSIS

2019 ◽  
Vol 3 (12) ◽  
Author(s):  
Shazia Khatoon ◽  
Samir Jain
Keyword(s):  
Oral Health ◽  
Periodontal Disease ◽  
Lipid Profile ◽  
Clinical Evaluation ◽  
Carotid Atherosclerosis ◽  
Periodontal Diseases ◽  
Control Group ◽  
World Population ◽  
Periodontal Tissues ◽  
Systemic Health

Periodontal disease is a disease characterized by inflammation of the periodontal tissues caused by microorganisms in the oral cavity and affects approximately 90% of the world population. Losses in the alveolar bone and connective tissue are observed due to periodontal diseases, which may lead to tooth loss. In addition, periodontal disease has been associated with many systemic diseases such as coronary artery diseases, stroke, head and neck cancer, pregnancy complications and diabetes. Periodontal disease is affected by risk factors such as smoking and diabetes, similar to vascular diseases. Hence based on above findings the present study was planned for Biochemical and Clinical Evaluation of Correlation of Periodontitis and Early Carotid Atherosclerosis. The present study was planned in Department of Dentistry, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar, India. In the present study 20 cases of the Generalized chronic Periodontitis were enrolled in the Group A as study group patients. And 20 cases of Periodontally healthy individuals were enrolled in Group B as control group patients for comparative evaluation. Under aseptic measures, venous blood samples were drawn by venipuncture in antecubital fossa using 5ml syringe and collected in a plain vacuum tubes and transported to clinical laboratory for lipid profile analysis. Both the groups were subjected for ultrasonography for the assessment of Carotid Intima-Media Thickness (IMT) and Lipid Profile. The data generated from the present study concluded that periodontal disease has association with early carotid atherosclerosis which is a risk factor for cardiovascular diseases .Thus oral health and systemic health are closely related and overall systemic health of an individual can be improved by maintaining a proper oral health regimen. It is important in terms of health policies that there is no need for an additional cost for this early diagnosis. Keywords: Periodontitis, Early Carotid Atherosclerosis, Heart disease, etc.

Periodontal disease and carotid atherosclerosis: Are hemodynamic forces a link?

2010 ◽  
Vol 213 (1) ◽  
pp. 263-267 ◽  
Author(s):  
Claudio Carallo ◽  
Leonzio Fortunato ◽  
Maria Serena de Franceschi ◽  
Concetta Irace ◽  
Cesare Tripolino ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Carotid Atherosclerosis ◽  
Hemodynamic Forces

C-reactive protein as a marker of progression of carotid atherosclerosis in subjects with type 2 diabetes mellitus

VASA ◽  
2017 ◽  
Vol 46 (3) ◽  
pp. 187-192 ◽  
Author(s):  
Aleš Pleskovič ◽  
Marija Šantl Letonja ◽  
Andreja Cokan Vujkovac ◽  
Jovana Nikolajević Starčević ◽  
Katarina Gazdikova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Carotid Atherosclerosis ◽  
Inflammatory Marker ◽  
Progression Rate ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Hs Crp ◽  
Unstable Plaques

Abstract. Background: This prospective study was designed to evaluate the effect of inflammatory markers on the presence and progression of subclinical markers of carotid atherosclerosis in a 3.8-year follow-up period in patients with type 2 diabetes mellitus (T2DM). Patients and methods: A total of 595 subjects with T2DM were enrolled. Subclinical markers of carotid atherosclerosis (carotid intima media thickness (CIMT), plaque thickness, and plaques presence) were assessed with ultrasound at the time of recruitment and again after 3.8 years. Subjects with T2DM were divided into 2 groups according to the plasma high sensitive C-reactive protein (hs-CRP) levels (subjects with hs-CRP ≥ 2 mg/L and subjects with hs-CRP below 2 mg/L). Results: Subjects with T2DM and hs-CRP levels ≥ 2 mg/L had higher CIMT in comparison with subjects with T2DM and hs-CRP levels below 2 mg/L, and higher incidence of plaques/unstable plaques in comparison with subjects with T2DM and hs-CRP levels below 2 mg/L. Multivariate logistic regression analysis found the association between the HDL cholesterol level and presence of plaques, whereas the inflammatory marker hs-CRP was not associated with subclinical markers of progression of carotid atherosclerosis. Multiple linear regression analysis found the association between the hs-CRP levels and either CIMT progression rate or a change in the number of sites with plaques in a 3.8-year follow-up. Conclusions: We demonstrated an association between the inflammatory marker hs-CRP and either CIMT or incidence of plaques/unstable plaques at the time of recruitment in Caucasians with T2DM. Moreover, we found the association between hs-CRP levels and either CIMT progression rate or a change in the number of sites with plaques in a 3.8-year follow-up in subjects with T2DM.

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