scholarly journals Treatment of Renal Cell Carcinoma in Elderly and Frail Patients

10.5772/27262 ◽  
2012 ◽  
Author(s):  
Mirjana Rajer
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Frail Patients

scholarly journals Stereotactic Body Radiotherapy for Frail Patients with Primary Renal Cell Carcinoma: Preliminary Results after 4 Years of Experience

Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3129
Author(s):  
Laure Grelier ◽  
Michael Baboudjian ◽  
Bastien Gondran-Tellier ◽  
Anne-Laure Couderc ◽  
Robin McManus ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Stereotactic Body Radiotherapy ◽  
Renal Cell ◽  
Dose Fractionation ◽  
Free Survival ◽  
Primary Renal Cell Carcinoma ◽  
Frail Patients ◽  
Fractionation Schedule ◽  
Tertiary Center

Introduction: The aim of this study was to report the oncological outcomes and toxicity of stereotactic body radiotherapy (SBRT) to treat primary renal cell carcinoma (RCC) in frail patients unfit for surgery or standard alternative ablative therapies. Methods: We retrospectively enrolled 23 patients who had SBRT for primary, biopsy-proven RCC at our tertiary center between October 2016 and March 2020. Treatment-related toxicities were defined using CTCAE, version 4.0. The primary outcome was local control which was defined using the Response Evaluation Criteria in Solid Tumors. Results: The median age, Charlson score and tumor size were 81 (IQR 79–85) years, 7 (IQR 5–8) and 40 (IQR 28–48) mm, respectively. The most used dose fractionation schedule was 35 Gy (78.3%) in five or seven fractions. The median duration of follow-up for all living patients was 22 (IQR 10–39) months. Local recurrence-free survival, event-free survival, cancer-specific survival and overall survival were 96 (22/23), 74 (18/23), 96 (22/23) and 83% (19/23), respectively. There were no grade 3–4 side effects. No patients required dialysis during the study period. No treatment-related deaths or late complications were reported. Conclusion: SBRT appears to be a promising alternative to surgery or ablative therapy to treat primary RCC in frail patients.

1253: Different Survival in PT3A Renal Cell Carcinoma with Sinus Fat Invasion or Perinephric Fat Invasion

2007 ◽  
Vol 177 (4S) ◽  
pp. 413-413
Author(s):  
Marco Roscigno ◽  
Roberto Bertini ◽  
Cesare Cozzarini ◽  
Alessandra Pasta ◽  
Mattia Sangalli ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Perinephric Fat

1252: Relative Survival Following Treatment for Renal Cell Carcinoma (RCC)- A S.E.E.R. Analysis: Is Age Important?

2007 ◽  
Vol 177 (4S) ◽  
pp. 413-413
Author(s):  
Yu-Ning Wong ◽  
Brian L. Egleston ◽  
Ismail R. Saad ◽  
Robert G. Uzzo
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Relative Survival

920: Pediatric Renal Cell Carcinoma: An Aggressive Tumor with Biologic Features Distinct From Its Adult Counterpart

2007 ◽  
Vol 177 (4S) ◽  
pp. 305-305
Author(s):  
Richard A. Ashley ◽  
Jonathan C. Routh ◽  
Sameer A. Siddiqui ◽  
Brant A. Inman ◽  
Thomas J. Sebo ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Pediatric Renal Cell Carcinoma ◽  
Aggressive Tumor

915: Prognosis and Survival of Synchronous Bilateral Renal Cell Carcinoma: A Multicenter Experience

2007 ◽  
Vol 177 (4S) ◽  
pp. 303-304 ◽  
Author(s):  
Tobias Klatte ◽  
Heiko Wunderlich ◽  
Jean-Jacques Patard ◽  
Mark D. Kleid ◽  
John S. Lam ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Bilateral Renal Cell Carcinoma

908: Preoperative C-Reactive Protein Elevation as a Predictor of Localized Renal Cell Carcinoma

2007 ◽  
Vol 177 (4S) ◽  
pp. 301-301
Author(s):  
Yasumasa Iimura ◽  
Kazutaka Saito ◽  
Minato Yokoyama ◽  
Hitoshi Masuda ◽  
Tsuyoshi Kobayashi ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Localized Renal Cell Carcinoma

506: A Risk-Adjusted Follow-up for Patients with Stage I and II Renal Cell Carcinoma

2007 ◽  
Vol 177 (4S) ◽  
pp. 169-169
Author(s):  
Quoc-Dien Trinh ◽  
Pierre I. Karakiewicz ◽  
Thierry Lebeau ◽  
Dan Lewinshtein ◽  
Elie Antebi ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Stage I
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