scholarly journals Infective Endocarditis in the Elderly

Endocarditis ◽  
10.5772/27101 ◽  
2012 ◽  
Author(s):  
Lucy Miller ◽  
Jim George
Author(s):  
Philippe Moreillon ◽  
Alain Bizzini ◽  
Yok Ai Que

2016 ◽  
Vol Volume 11 ◽  
pp. 1199-1206 ◽  
Author(s):  
Emmanuel Forestier ◽  
Thibaut Fraisse ◽  
Claire Roubaud-Baudron ◽  
Christine Selton-Suty ◽  
Leonardo Pagani

2015 ◽  
Vol 31 (1) ◽  
pp. 41-49 ◽  
Author(s):  
Xabier García-Albéniz ◽  
John Hsu ◽  
Marc Lipsitch ◽  
Roger W. Logan ◽  
Sonia Hernández-Díaz ◽  
...  

2007 ◽  
Vol 16 ◽  
pp. S73-S74
Author(s):  
M. Alasady ◽  
D. Sathianathan ◽  
D. Coles ◽  
A. Farshid ◽  
D. McGill ◽  
...  

2019 ◽  
Author(s):  
Zhenzhu Wu ◽  
Yi Chen ◽  
Tingting Xiao ◽  
Tianshui Niu ◽  
Qingyi Shi ◽  
...  

Abstract Background Infective endocarditis (IE) is a serious disease, with a worse prognosis in the elderly. Aims To explore the clinical features and prognosis of old patients with IE in a tertiary hospital. Methods A retrospective cohort study was conducted. A total of 407 patients diagnosed as IE were divided into two groups: 348 patients under 65 years old and 59 patients over 65 years old. Results For older patients, clinical symptoms such as fever, anemia, and heart murmur were as common as in younger patients. Comorbidities like hypertension (P<0.001) and diabetes (P=0.023) were more common in older patients. Complications like renal insufficiency (P=0.027) and arrhythmia (P<0.001) were also more common in older patients. The old patients had a lower operation rate (40.7% vs 60.6%, P=0.004) and higher in-hospital mortality (20.3% vs 8.9%, P=0.008) compared with the younger patients. Pitt score ≥4 (P=0.043, OR=28.0, 95% CI 1.1-700.4) and renal insufficiency (P=0.011, OR=34.2, 95% CI 2.2-521.2) were independent risk factors of in-hospital mortality for older patients. Surgical treatment was a significant predictor of one-year mortality even after adjusting for the confounders (HR = 1.722, 95% CI 0.563-5.365, P = 0.005).The one-year survival rate was higher for older patients with surgical intervention than those without (95.8% vs 68.6%, P=0.007). Conclusions IE in older patients present with more comorbidities and complications as well as a higher mortality than younger patients. Surgery were underused in old patients and old patients with surgical treatment had better long-term prognosis.


2021 ◽  
Vol 3 (4) ◽  
pp. 350-355
Author(s):  
Uğur Küçük ◽  
◽  
Sevil Alkan ◽  
Cemile Uyar ◽  
◽  
...  

Introduction: Although infective endocarditis (IE) is rare disease, this disease has importance due to its high morbidity and mortality rates. The exact incidence is not known as it is not a reportable disease. Unlike developed countries, the disease affects the young more than the elderly in developing countries. Most of the time, the diagnosis cannot be made at the first examination and the disease is often overlooked. In order to reduce the mortality and morbidity of this disease, it is important to quickly recognize the disease by following current diagnosis and treatment methods, to identify the causative agent and to treat accordingly. Both the epidemiology and the management of IE are changing due to medical advances. This situation may also be reflected in scientific publications. We aimed to analyze the global researches on IE. Material and methods: The Scopus database was searched for bibliometric analysis without selecting document type. Data were retrieved for the time period January 1, 1940 and Semptember 26, 2021, containing the keywords " Infective’’ and’’endocarditis " in their title. Results: 7911 publications were included in the study. The first publication was made in the year 1891. Most of the publications were research articles [n=5784 (73.11%)] and were from the United States of America (USA) [n =1622 (20.50%)]. Japan, France, United Kingdom and Spain were also in the top 5 publishing countries on IE. Conclusions: Infective endocarditis is still an important reason of mortality, and there are many unanswered questions about the managament and preventation of this disease. This situation reflected the scientific publications. Since this is a global problem, not just some developed countries involved in the IE research, also more countries should be encouraged to participate the studies on IE.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Zhenzhu Wu ◽  
Yi Chen ◽  
Tingting Xiao ◽  
Tianshui Niu ◽  
Qingyi Shi ◽  
...  

Abstract Background Infective endocarditis (IE) especially in the elderly is a serious disease, with a worse prognosis. Methods A retrospective cohort study was conducted. A total of 405 patients with definite IE were divided into three groups: 205 patients under 50 years old, 141 patients between 50 and 64 years old and 59 patients over 65 years old. Results For older patients, clinical symptoms such as fever, anemia, and heart murmur were as common as the younger patients. IE in old patients had more frequent nosocomial origin (P = 0.007) and tended to be more frequent with bad oral hygiene (p = 0.008). The most frequent isolated pathogens in the old groups was streptococci and coagulase-negative staphylococci. The old patients had a lower operation rate (40.7% vs 58.9% vs 62.4%, P = 0.012) and higher in-hospital mortality (20.3% vs 10.6% vs 8.8%, P = 0.044) compared with the younger patients. Surgical treatment was a significant predictor of one-year mortality even after adjusting for the confounders (HR = 2.45, 95% CI 1.027–10.598, P = 0.009). The one-year survival rate was higher for older patients with surgical intervention than those without (95.8% vs 68.6%, P = 0.007). Conclusions Older patients with IE presented with more comorbidities, bad oral hygiene, more nosocomial origin and a more severe prognosis than younger patients. Streptococci was the most frequent micro-organisms in this group. Surgery were underused in old patients and those with surgical treatment had better prognosis.


The Lancet ◽  
1923 ◽  
Vol 201 (5192) ◽  
pp. 460
Author(s):  
DavidA. Alexander

Gerontology ◽  
2007 ◽  
Vol 53 (5) ◽  
pp. 245-249 ◽  
Author(s):  
Leopoldo Pérez de Isla ◽  
José Zamorano ◽  
Vera Lennie ◽  
Jorge Vázquez ◽  
José Manuel Ribera ◽  
...  

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