scholarly journals Trigger Factors, Allergens and Allergy Testing in Atopic Dermatitis

10.5772/27058 ◽  
2012 ◽  
Author(s):  
Evmorfia Ladoyanni
Keyword(s):  
Atopic Dermatitis ◽  
Trigger Factors ◽  
Allergy Testing

scholarly journals Management of patients with atopic dermatitis during pregnancy

2021 ◽  
Author(s):  
Е.А. Орлова ◽  
О.П. Виноградова ◽  
Е.М. Костина ◽  
Ю.А. Кандрашкина
Keyword(s):  
Atopic Dermatitis ◽  
Pregnant Woman ◽  
Early Diagnosis ◽  
Pregnant Women ◽  
Clinical Studies ◽  
Allergic Diseases ◽  
Close Attention ◽  
Trigger Factors ◽  
Complex Therapy ◽  
Degree Of Risk

Проблема особенностей течения аллергических заболеваний на фоне беременности, а также рациональные и безопасные подходы к их лечению находятся в фокусе пристального внимания специалистов. В статье представлена клинико-патогенетическая характеристика атопического дерматита у беременных женщин. Уделяется внимание принципам диагностики атопического дерматита при беременности. Ранняя диагностика особенно важна при наступлении беременности, поскольку у детей, рожденных в семье, где оба родителя страдают атопией, риск развития атопического дерматита равняется 75%. В первую очередь для профилактики возможных обострений атопического дерматита у беременных необходимо решить вопрос с ликвидацией триггерных факторов и исключить контакт с аллергенами, особое внимание следует уделять гипоаллергенной диете. Рассматриваются вопросы выбора тактики ведения и терапии дерматоза с учетом клинических исследований, оценки степени риска для беременной и плода. Обсуждаются особенности применения эмолентов, топических глюкокортикостероидов, топических противозудных средств, седативных и антигистаминных препаратов в составе комплексной терапии беременных с атопическим дерматитом. The problem of the peculiarities of the course of allergic diseases during pregnancy, as well as rational and safe approaches to their treatment, is in the focus of close attention of specialists. The article presents the clinical and pathogenetic characteristics of atopic dermatitis in pregnant women. Attention is paid to the principles of diagnosis of atopic dermatitis during pregnancy. Early diagnosis is especially important when pregnancy occurs, since children born to a family where both parents have atopy have a 75% risk of developing atopic dermatitis. First of all, for the prevention of possible exacerbations of atopic dermatitis in pregnant women, it is necessary to resolve the issue of eliminating trigger factors and exclude contact with allergens, special attention should be paid to a hypoallergenic diet. The issues of the choice of tactics of management and therapy of dermatosis are considered, taking into account clinical studies, assessment of the degree of risk for the pregnant woman and the fetus. The features of the use of emollients, topical glucocorticosteroids, topical antipruritic agents, sedatives and antihistamines as part of the complex therapy of pregnant women with atopic dermatitis are discussed.

scholarly journals PROFIL DERMATITIS ATOPIK DI POLIKLINIK KULIT DAN KELAMIN RSUP PROF. DR. R.D KANDOU MANADO PERIODE JANUARI 2010 - DESEMBER 2012

2015 ◽  
Vol 7 (3) ◽  
Author(s):  
Juan P. E. Febriansyah ◽  
Grace M. Kapantow ◽  
Agus Hariyanto
Keyword(s):  
Atopic Dermatitis ◽  
Retrospective Study ◽  
Topical Corticosteroid ◽  
Inflammatory Disease ◽  
Medical Records ◽  
Clinical Manifestations ◽  
Age Group ◽  
Trigger Factors ◽  
Infancy And Childhood ◽  
Almost All

Abstract: Atopic dermatitis (AD) is a chronic and recurrent inflammatory disease most commonly found during infancy and childhood. This disease is very complex and has a variety of clinical manifestations. Its management depends not only on the medication, but also on skin care and avoidance of trigger factors. This study aimed to obtain the profile of atopic dermatitis at the Dermatovenerology Clinic of Prof. Dr. R. D. Kandou Hospital Manado period January 2010 to December 2012. This was a retrospective study using medical records of new registered patients at the Dermatovenerology clinic. New cases were grouped according to sex, age, occupation, treatment, and coinfection diseases. The results showed that there were 461 (16.26%) new cases of AD out of 2,835 cases, consisted of 289 (62.69%) females and 172 (37.31%) males with a ratio of 1.7:1. The most frequent age group was >12 years old (58.35%); they were commonly students (43.38%). The most frequent treatment was a combination of oral antihistamin and topical corticosteroid (49.67%). No coinfection was recorded among 332 cases (72.02%). Conclusion: Most of the atopic dermatitis cases at the Dermatovenerology Clinic of Prof. Dr. R. D. Kandou Hospital Manado for the last 3 years were females, age group >12 years old, and as students. Combination of oral antihistamin and topical corticosteroid was the most common treatment. Almost all cases had no coinfection.Keywords: atopic dermatitis, profileAbstrak: Dermatitis atopik (DA) merupakan penyakit peradangan kulit kronis dan residif yang sering terjadi pada masa bayi dan kanak-kanak. Penyakit ini sangat kompleks dengan gambaran klinis bervariasi. Penatalaksanaannya tidak hanya bergantung pada pengobatan, namun juga perawatan kulit dan menghindari faktor pencetus. Penelitian ini bertujuan untuk mendapatkan profil DA di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2010 - Desember 2012. Metode penelitian ini retrospektif dengan menggunakan catatan medik pasien baru di Poliklinik Kulit dan Kelamin tersebut. Kasus baru dikelompokkan menurut jenis kelamin, usia, pekerjaan, pengobatan, dan penyakit penyerta. Hasil penelitian memperlihatkan 461 (16,26%) kasus baru DA dari 2.835 kasus baru, terdiri dari 289 (62,69%) perempuan dan 172 (37,31%) laki-laki dengan rasio 1,7:1. Kelompok usia terbanyak ialah >12 tahun sebesar 269 (58,35%), terbanyak pada pelajar/mahasiswa yaitu 200 kasus (43,38%). Terapi tersering ialah kombinasi antihistamin oral dan kortikosteroid topikal sejumlah 229 kasus (49,67%). Sejumlah 332 (72,02%) kasus tidak disertai penyakit lain. Simpulan: Kasus dermatitis atopik di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado selama 3 tahun terakhir tersering pada perempuan, kelompok usia >12 tahun, dan pada pelajar/mahasiswa. Kombinasi anti histamin oral dan kortikosteroid topikal menjadi terapi yang tersering diberikan. Sebagian besar kasus tidak disertai penyakit lain.Kata kunci: dermatitis atopik, profil

scholarly journals Atopic Dermatitis and Fungi

2002 ◽  
Vol 15 (4) ◽  
pp. 545-563 ◽  
Author(s):  
Jan Faergemann
Keyword(s):  
Atopic Dermatitis ◽  
Standard Treatment ◽  
Neck Region ◽  
Antifungal Drugs ◽  
House Dust Mites ◽  
Dust Mites ◽  
Dry Skin ◽  
Trigger Factors ◽  
Head And Neck Region

SUMMARY Atopic dermatitis (AD) is a chronic, itching, inflammatory skin disease which is associated with asthma and/or hay fever and a familial occurrence of these conditions. Genetic factors are important in the development of AD, but the exact hereditary pathway is still unknown. Dry skin and the weakened barrier function in patients with AD is very important for the patient's reactions to irritants and other external trigger factors including microorganisms. The standard treatments are topical corticosteroids, topical immunomodulating agents, and emollients. If AD cannot be controlled by this type of treatment, systemic immunomodulating agents may be used. UVB, UVA, or psoralen-UVA may also be used for widespread severe lesions. However, some patients do not respond to these standard treatment, and then it is important to consider the role of microorganisms, house dust mites or food. The role of the Malassezia yeasts in AD, especially AD located to the head and neck region, is now documented in several papers. There are also several papers indicating the role of Candida as an aggravating factor in AD. Patients with AD also develop chronic dermatophyte infections more easily, and patients with AD and chronic dermatophyte infections may show improvement in their AD when treated with antifungal drugs.

Diagnostic specificity of the Fcε-receptor based allergy screening test

2009 ◽  
Vol 37 (04) ◽  
pp. 239-243
Author(s):  
R. Neiger ◽  
M. Linek ◽  
N. Thom
Keyword(s):  
Atopic Dermatitis ◽  
House Dust ◽  
Screening Test ◽  
Skin Diseases ◽  
Specific Ige ◽  
House Dust Mites ◽  
Dust Mites ◽  
Diagnostic Specificity ◽  
Allergen Specific Immunotherapy ◽  
Allergy Testing

Summary Objective: To evaluate the diagnostic specificity of a Fcε-receptor allergy screening test using serum from clinically non-atopic dogs. Material and methods: In this prospective study allergen-specific IgE levels were measured using the Fcε-receptor method (Allercept® Heska) in the serum from 15 clinically non-atopic dogs, without any history of pruritic skin diseases or recurrent ear diseases. Five crossbreeds and 10 pure breed dogs were included with approximately equal sex distribution. Their age ranged between 2 and 14 years, with a median age of 4 years. A commercially available allergy screening test was performed evaluating three allergen groups: mites (house dust mites and forage mites), moulds and pollens, as well as flea-saliva. Results: All except one dog showed positive results for at least one of the allergen groups. Fourteen dogs were positive for mites (house dust mites and forage mites), five dogs each were additionally positive for flea-saliva antigen and for pollens, respectively; only one dog was positive for moulds. Overall diagnostic specificity of the allergy screening test was 6.7% for mites, 66.6% for flea-saliva and pollens and 93.3% for moulds. Conclusions: The Fcε-receptor based allergy screening test detects a high incidence of allergen-specific IgE among clinically non-atopic dogs. The low diagnostic specificity in this study confirms results of earlier studies with serological monoclonal and polyclonal allergy testing. Clinical relevance: This Fcε-receptor based allergy screening test should not be used to establish the diagnosis of canine atopic dermatitis. Diagnosis of atopic dermatitis in dogs is based on clinical criteria and exclusion of other causes of pruritus. Positive intradermal or serological allergy testing is only a minor diagnostic criterion. Any kind of allergy testing is performed for identification of the relevant allergens in atopic dogs as a precondition for allergen specific immunotherapy.

Challenge of food allergy testing and avoidance in children with atopic dermatitis

2021 ◽  
Vol 14 (6) ◽  
pp. e243141
Author(s):  
Stephanie Ann Kubala ◽  
Paula Mariam Mohyi ◽  
Kristin Sokol ◽  
Pamela Frischmeyer-Guerrerio
Keyword(s):  
Primary Care ◽  
Atopic Dermatitis ◽  
Food Allergy ◽  
Growth Failure ◽  
Clinical History ◽  
Primary Care Providers ◽  
Care Providers ◽  
Immediate Hypersensitivity ◽  
Allergy Testing ◽  
Food Avoidance

Atopic dermatitis (AD) is a common presenting complaint by children and their caretakers to their primary care providers. On testing, children with AD frequently exhibit positive food-specific IgE levels in the absence of immediate allergic reactions. Misinterpretation of these false positive tests can lead to unnecessary food avoidance, which can have tremendous psychosocial, economic and nutritional consequences and, in some cases, facilitate the development of an immediate hypersensitivity to the food. We present a child with persistent AD who underwent broad testing that led to unnecessary food avoidance resulting in Vitamin D deficiency, growth failure and the development of an IgE-mediated food allergy. This case underscores the need for caution by primary care clinicians in using food avoidance diets as a treatment for AD and the importance of limiting allergy testing to foods only when the clinical history indicates an immediate hypersensitivity reaction.

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