scholarly journals Current Status: Mexican Medicinal Plants with Insecticidal Potential

Author(s):  
Ludmila Elisa ◽  
Laura P. ◽  
Graciela Bustos-Zagal ◽  
Victor M.
2019 ◽  
Vol 20 (12) ◽  
pp. 1227-1243
Author(s):  
Hina Qamar ◽  
Sumbul Rehman ◽  
D.K. Chauhan

Cancer is the second leading cause of morbidity and mortality worldwide. Although chemotherapy and radiotherapy enhance the survival rate of cancerous patients but they have several acute toxic effects. Therefore, there is a need to search for new anticancer agents having better efficacy and lesser side effects. In this regard, herbal treatment is found to be a safe method for treating and preventing cancer. Here, an attempt has been made to screen some less explored medicinal plants like Ammania baccifera, Asclepias curassavica, Azadarichta indica, Butea monosperma, Croton tiglium, Hedera nepalensis, Jatropha curcas, Momordica charantia, Moringa oleifera, Psidium guajava, etc. having potent anticancer activity with minimum cytotoxic value (IC50 >3μM) and lesser or negligible toxicity. They are rich in active phytochemicals with a wide range of drug targets. In this study, these medicinal plants were evaluated for dose-dependent cytotoxicological studies via in vitro MTT assay and in vivo tumor models along with some more plants which are reported to have IC50 value in the range of 0.019-0.528 mg/ml. The findings indicate that these plants inhibit tumor growth by their antiproliferative, pro-apoptotic, anti-metastatic and anti-angiogenic molecular targets. They are widely used because of their easy availability, affordable price and having no or sometimes minimal side effects. This review provides a baseline for the discovery of anticancer drugs from medicinal plants having minimum cytotoxic value with minimal side effects and establishment of their analogues for the welfare of mankind.


2019 ◽  
Vol 3 (8) ◽  
pp. 137-144
Author(s):  
Saurabh Nimesh ◽  
Vrish Dhwaj Ashwlayan ◽  
Pankaj Barman

Author(s):  
Gadisa Melkamu Bulcha ◽  
Kebebush Zepre

Incomplete coverage of the modern medical system, shortage of pharmaceuticals, and unaffordable prices of modern drugs, make the majority of Ethiopians still depend on traditional plant medicine. Therefore, this study is aimed to assess the current status of indigenous knowledge of traditional plant medicine used among communities of Won chi District. Method: A total of 198 informants (27 key and 171 general) were selected purposively based on the availability of key informants and vegetation richness of the District. semi-structured interview, observation, and guided field walk with informants were data collection methods. Ethnobotanical scoring and ranking methods like informant consensus, paired-wise comparison, and preference ranking were used to analyze the collected data. The findings were displayed using tables and figures. Result: A total of 93 medicinal plant species were identified. Out of these,50 species (53.76%)were noted to treat only human ailments, 3(2.23%) species were used to treat livestock ailments and the rest 40 (43.01%) were used to treat both. Nearly two-thirds of the study participants have good knowledge about traditional plant medicine use. most medicinal plants were reported by elders (94.62%) than younger age group, traditional medicinal plant healers almost know all (96.77%), regarding religion waqefata (60.21%) know than other religion. More medicinal plants were reported by males (86.02%)than females, while regarding educational status illiterate (61.29%)know and mention more Medicinal plants than literate. Therefore, all stakeholders should work together in changing the current situation in order to sustainably benefit from traditional plant medicine.


2021 ◽  
Vol 12 ◽  
Author(s):  
Ziwei Hu ◽  
Jinhong Lin ◽  
Jintao Chen ◽  
Tengxi Cai ◽  
Lixin Xia ◽  
...  

Viral pneumonia has been a serious threat to global health, especially now we have dramatic challenges such as the COVID-19 pandemic. Approximately six million cases of community-acquired pneumonia occur every year, and over 20% of which need hospital admission. Influenza virus, respiratory virus, and coronavirus are the noteworthy causative agents to be investigated based on recent clinical research. Currently, anaphylactic reaction and inflammation induced by antiviral immunity can be incriminated as causative factors for clinicopathological symptoms of viral pneumonia. In this article, we illustrate the structure and related infection mechanisms of these viruses and the current status of antiviral therapies. Owing to a set of antiviral regiments with unsatisfactory clinical effects resulting from side effects, genetic mutation, and growing incidence of resistance, much attention has been paid on medicinal plants as a natural source of antiviral agents. Previous research mainly referred to herbal medicines and plant extracts with curative effects on viral infection models of influenza virus, respiratory virus, and coronavirus. This review summarizes the results of antiviral activities of various medicinal plants and their isolated substances, exclusively focusing on natural products for the treatment of the three types of pathogens that elicit pneumonia. Furthermore, we have introduced several useful screening tools to develop antiviral lead compounds.


2020 ◽  
Vol 21 (5) ◽  
pp. 443-487
Author(s):  
Snober Shabeer Wani ◽  
Parvaiz A. Dar ◽  
Sajad M. Zargar ◽  
Tanveer A. Dar

Biologically active molecules obtained from plant sources, mostly including secondary metabolites, have been considered to be of immense value with respect to the treatment of various human diseases. However, some inevitable limitations associated with these secondary metabolites like high cytotoxicity, low bioavailability, poor absorption, low abundance, improper metabolism, etc., have forced the scientific community to explore medicinal plants for alternate biologically active molecules. In this context, therapeutically active proteins/peptides from medicinal plants have been promoted as a promising therapeutic intervention for various human diseases. A large number of proteins isolated from the medicinal plants have been shown to exhibit anti-microbial, anti-oxidant, anti-HIV, anticancerous, ribosome-inactivating and neuro-modulatory activities. Moreover, with advanced technological developments in the medicinal plant research, medicinal plant proteins such as Bowman-Birk protease inhibitor and Mistletoe Lectin-I are presently under clinical trials against prostate cancer, oral carcinomas and malignant melanoma. Despite these developments and proteins being potential drug candidates, to date, not a single systematic review article has documented the therapeutical potential of the available biologically active medicinal plant proteome. The present article was therefore designed to describe the current status of the therapeutically active medicinal plant proteins/peptides vis-à-vis their potential as future protein-based drugs for various human diseases. Future insights in this direction have also been highlighted.


2020 ◽  
Vol 8 ◽  
Author(s):  
M.R. Kholikulov

In  the southern part of  Kurama mountains of  North Fergana near Havasay, Chadaksay and Rezaksay  on   the  relatively large areas of medicinal plants found  Eremurus sogdiana, Perovskija scrophulariifolia and other species.  And Ferula tenuisecta,  Prangos pabularia, Ligularia alpigena, Lagotis korolkovii, Festuca valesiaca and others meet  on  the Angren plateau


2013 ◽  
Vol 1 (2) ◽  
pp. 73
Author(s):  
Kaliappan Ilango ◽  
Ananth kumar Kammalla ◽  
Govind Prasad Dubey ◽  
Aruna Agrawal

2013 ◽  
Vol 2 (3) ◽  
pp. 179-188 ◽  
Author(s):  
Ramandeep Singh ◽  
Ashraf Ali ◽  
Gaurav Gupta ◽  
Alok Semwal ◽  
G. Jeyabalan

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