scholarly journals Ulcerative Colitis in Children and Adolescents

10.5772/26743 ◽  
2011 ◽  
Author(s):  
Andrew S. ◽  
Daniel A.
Keyword(s):  
Ulcerative Colitis ◽  
Children And Adolescents

scholarly journals Tu1196 Evaluation of the Pharmacokinetics and Safety of MMX Mesalamine Following Administration in Children and Adolescents With Ulcerative Colitis

2014 ◽  
Vol 146 (5) ◽  
pp. S-781
Author(s):  
Carmelo Cuffari ◽  
David M. Pierce ◽  
Bartosz Korczowski ◽  
Krzysztof Fyderek ◽  
Heather Van Heusen ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Children And Adolescents

High Incidence of Upper Gastrointestinal Tract Involvement in Children With Crohn Disease

PEDIATRICS ◽  
1989 ◽  
Vol 83 (5) ◽  
pp. 777-781
Author(s):  
C. Lenaerts ◽  
C. C. Roy ◽  
M. Vaillancourt ◽  
A. M. Weber ◽  
C. L. Morin ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Gastrointestinal Tract ◽  
Children And Adolescents ◽  
Chronic Ulcerative Colitis ◽  
Crohn Disease ◽  
Bowel Disease ◽  
Upper Gastrointestinal Tract ◽  
Indeterminate Colitis ◽  
Gastrointestinal Lesions ◽  
Upper Gastrointestinal

This retrospective study of Crohn disease in 230 children and adolescents with a mean age of 12.5 years at the time of diagnosis and an average follow-up of 6.6 years showed that 30% had lesions of the esophagus, stomach, and duodenum. Three patients had Crohn disease isolated to the upper gastrointestinal tract. The 169 patients with both small and large bowel disease were at greater risk (33%, P < .05) of having upper gastrointestinal lesions than the 37 with isolated small bowel disease and the 21 with disease limited to the colon and/ or rectum. An aggregate of symptoms and signs more likely present in those with upper gastrointestinal involvement included: dysphagia, pain when eating, nausea and/or vomiting, and aphthous lesions of the mouth. Furthermore, weight loss was more severe and hypoalbuminemia more frequent. Because upper gastrointestinal series x-ray studies failed to detect upper gastrointestinal lesions in 13 patients of 69 of those with upper gastrointestinal disease, endoscopy should be considered in all children and adolescents in whom a diagnosis of Crohn disease is entertained. Endoscopy and biopsy of the upper gastrointestinal tract should be done in any patient with symptoms suggestive of proximal involvement. Finally, in view of the fact that endoscopy established the diagnosis of Crohn disease in five patients previously thought to have chronic ulcerative colitis, the procedure should routinely be performed in all patients with chronic ulcerative colitis or indeterminate colitis before surgery is performed.

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