scholarly journals Central Nervous System Involvement from Epithelial Ovarian Cancer

Author(s):  
Gennaro Cormio ◽  
Maddalena Falagario ◽  
Luigi E.
2011 ◽  
Vol 114 (2) ◽  
pp. 133-136 ◽  
Author(s):  
Gennaro Cormio ◽  
Vera Loizzi ◽  
Maddalena Falagario ◽  
Andrea A. Lissoni ◽  
Leonardo Resta ◽  
...  

Cells ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 3408
Author(s):  
Giulia Scotto ◽  
Fulvio Borella ◽  
Margherita Turinetto ◽  
Valentina Tuninetti ◽  
Anna A. Valsecchi ◽  
...  

Epithelial ovarian cancer (EOC) is the leading cause of death among women affected by gynaecological malignancies. Most patients show advanced disease at diagnosis (FIGO stage III-IV) and, despite the introduction of new therapeutic options, most women experience relapses. In most cases, recurrence is abdominal-pelvic; however, EOC can occasionally metastasize to distant organs, including the central nervous system. The incidence of brain metastases (BMs) from EOC is low, but it has grown over time; currently, there are no follow-up strategies available. In the last decade, a few biomarkers able to predict the risk of developing BMs from OC or as potential therapeutic targets have been investigated by several authors; to date, none have entered clinical practice. The purpose of this review is to offer a summary on the role of the most relevant predictors of central nervous system (CNS) involvement (hormone receptors; BRCA; MRD1; PD-1/PD-L1) and to highlight possible therapeutic strategies for the management of metastatic brain disease in EOC


2001 ◽  
Vol 21 (3) ◽  
pp. 291-292 ◽  
Author(s):  
Hüseyin Çaksen ◽  
Dursun Odabaş ◽  
Şükrü Arslan ◽  
Ahmet Faik Oner

2013 ◽  
Vol 48 (1) ◽  
pp. 71-77 ◽  
Author(s):  
Clarissa M. Comim ◽  
Bruna P. Mendonça ◽  
Diogo Dominguini ◽  
Andreza L. Cipriano ◽  
Amanda V. Steckert ◽  
...  

2003 ◽  
Vol 10 (3) ◽  
pp. 244-253 ◽  
Author(s):  
Lalit Kumar ◽  
Suchitra Barge ◽  
Ashok K. Mahapatra ◽  
Sanjay Thulkar ◽  
Gaura Kishore Rath ◽  
...  

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