scholarly journals Accurate Measurement of Systemic Oxygen Consumption in Ventilated Children with Congenital Heart Disease

10.5772/26557 ◽  
2012 ◽  
Author(s):  
Jia Li
Keyword(s):  
Congenital Heart Disease ◽  
Oxygen Consumption ◽  
Heart Disease ◽  
Congenital Heart ◽  
Systemic Oxygen

scholarly journals Systemic oxygen transport in patients with congenital heart disease.

Circulation ◽  
1987 ◽  
Vol 75 (2) ◽  
pp. 360-368 ◽  
Author(s):  
W Berman ◽  
S C Wood ◽  
S M Yabek ◽  
T Dillon ◽  
R R Fripp ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Oxygen Transport ◽  
Congenital Heart ◽  
Systemic Oxygen

scholarly journals Mechanism of Dyspnea during Exercise in Children with Corrected Congenital Heart Disease

2021 ◽  
Vol 19 (1) ◽  
pp. 99
Author(s):  
Mehdi Chlif ◽  
Mohamed Mustapha Ammar ◽  
Noureddine Ben Said ◽  
Levushkin Sergey ◽  
Said Ahmaidi ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Oxygen Consumption ◽  
Heart Disease ◽  
Exercise Test ◽  
Exercise Performance ◽  
Congenital Heart ◽  
Isometric Force ◽  
Surgical Correction ◽  
Time To Exhaustion ◽  
Peripheral Muscle

This study will evaluate cardiorespiratory and peripheral muscle function and their relationship with subjective dyspnea threshold after the surgical correction of congenital heart disease in children. Thirteen children with surgically repaired congenital heart disease were recruited. Each participant performed an incremental exercise test on a cycle ergometer until exhaustion. Gas exchanges were continuously sampled to measure the maximal aerobic parameters and ventilatory thresholds. The functional capacity of the subjects was assessed with a 6 min walk test. At the end of the exercise test, isokinetic Cybex Norm was used to evaluate the strength and endurance of the knee extensor muscle in the leg. Dyspnea was subjectively scored with a visual analog scale during the last 15 s of each exercise step. Oxygen consumption measured at the dyspnea score/VO2 relationship located at the dyspnea threshold, at which dyspnea suddenly increased. Results: The maximal and submaximal values of the parameters describing the exercise and the peripheral muscular performances were: VO2 Peak: 33.8 ± 8.9 mL·min−1·kg−1; HR: 174 ± 9 b·min−1; VEmax: 65.68 ± 15.9 L·min−1; P max: 117 ± 27 W; maximal voluntary isometric force MVIF: 120.8 ± 41.9 N/m; and time to exhaustion Tlim: 53 ± 21 s. Oxygen consumption measured at the dyspnea threshold was related to VO2 Peak (R2 = 0.74; p < 0.01), Tlim (R2 = 0.78; p < 0.01), and the distance achieved during the 6MWT (R2 = 0.57; p < 0.05). Compared to the theoretical maximal values for the power output, VO2, and HR, the surgical correction did not repair the exercise performance. After the surgical correction of congenital heart disease, exercise performance was impeded by alterations of the cardiorespiratory function and peripheral local factors. A subjective evaluation of the dyspnea threshold is a reliable criterion that allows the prediction of exercise capacity in subjects suffering from congenital heart disease.

RELATIVE HYPERMETABOLISM IN INFANTS WITH CONGENITAL HEART DISEASE AND UNDERNUTRITION

PEDIATRICS ◽  
1965 ◽  
Vol 36 (2) ◽  
pp. 183-191
Author(s):  
Martin H. Lees ◽  
J. David Bristow ◽  
Herbert E. Griswold ◽  
Richard W. Olmsted
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Congenital Heart Disease ◽  
Oxygen Consumption ◽  
Heart Disease ◽  
Clinical Finding ◽  
Congenital Heart ◽  
Normal Growth ◽  
Respiratory Systems ◽  
Weight For Age

1. Twenty-one infants with various forms of congenital heart disease leading to congestive heart failure, arterial unsaturation, or a combination of both events were studied with respect to resting oxygen consumption. Comparison was made with 21 control infants considered to be of normal growth and to have normal cardiac and respiratory systems. 2. Mean oxygen consumption for infants with heart disease was 9.3±2.4 ml/min/ kg compared to 7.3±0.8 ml/mm/kg for controls. Markedly undergrown infants with heart disease (60% or less of the 50th percentile weight for age) had a mean oxygen consumption of 10.9±1.4 ml/mm/kg compared to a mean of 7.5±2.0 ml/min/kg for infants with heart disease who were greater than 60% of the 50th percentile weight for age. Relative hypermetabolism seemed to relate to the degree of undernutrition rather than to any specific clinical finding. 3. Possible mechanisms of undernutrition and of relative hypermetabolism in the infant with heart disease are discussed.

scholarly journals Reduced Fetal Cerebral Oxygen Consumption Is Associated With Smaller Brain Size in Fetuses With Congenital Heart Disease

Circulation ◽  
2015 ◽  
Vol 131 (15) ◽  
pp. 1313-1323 ◽  
Author(s):  
Liqun Sun ◽  
Christopher K. Macgowan ◽  
John G. Sled ◽  
Shi-Joon Yoo ◽  
Cedric Manlhiot ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Oxygen Consumption ◽  
Heart Disease ◽  
Congenital Heart ◽  
Brain Size ◽  
Cerebral Oxygen ◽  
Cerebral Oxygen Consumption

Maximal versus sub-maximal effort during cardiopulmonary exercise testing in adults with congenital heart disease: outcome analysis of short-term cardiac-related events

2020 ◽  
pp. 1-6
Author(s):  
Bibhuti B. Das ◽  
Aliana Godoy ◽  
Talya Kadish ◽  
Jianli Niu
Keyword(s):  
Congenital Heart Disease ◽  
Oxygen Consumption ◽  
Heart Disease ◽  
Oxygen Uptake ◽  
Congenital Heart ◽  
Respiratory Exchange Ratio ◽  
Adult Congenital Heart Disease ◽  
Short Term ◽  
Adult Congenital ◽  
Oxygen Uptake Efficiency Slope

Abstract Peak respiratory exchange ratio is an objective marker of patient effort during cardiopulmonary exercise testing. We evaluated exercise variables in 175 adult congenital heart disease patients and the impact of respiratory exchange ratio on the prognostic value of exercise variables for short-term cardiac-related events. Of 175 patients, 110 completed the exercise test with a peak respiratory exchange ratio of ≥1.10 and the remaining 65 had a peak respiratory exchange ratio of <1.10. Peak oxygen consumption, the percentage of oxygen consumption at the ventilatory threshold, peak heart rate, percentage predicted peak heart rate, double product, oxygen uptake efficiency slope, and the number of patients with exercise oscillatory ventilation were reduced significantly in patients with a respiratory exchange ratio of <1.10 compared to those with a respiratory exchange ratio of ≥1.10. After a median follow-up of 21 months, total cardiac-related events occurred in 37 (21%) patients. Multivariate Cox proportional hazard analysis showed that the percentage predicted peak oxygen consumption, and oxygen uptake efficiency slope were independent predictors of cardiac-related events only in patients with a peak respiratory exchange ratio of ≥1.10. Sub-maximal exercise performance can be preserved in adult congenital heart disease patients. The percentage predicted oxygen consumption and the oxygen uptake efficiency slope are two independent predictors for short-term cardiac-related events in adult congenital heart disease patients.

scholarly journals Validity of the LaFarge equation for estimation of oxygen consumption in ventilated children with congenital heart disease younger than 3 years—A revisit

2010 ◽  
Vol 160 (1) ◽  
pp. 109-114 ◽  
Author(s):  
Jennifer Rutledge ◽  
Andrew Bush ◽  
Lara Shekerdemian ◽  
Ingram Schulze-Neick ◽  
Daniel Penny ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Oxygen Consumption ◽  
Heart Disease ◽  
Congenital Heart
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