scholarly journals The Role of Platelet Gel in Regenerative Medicine

10.5772/26130 ◽  
2011 ◽  
Author(s):  
Primoz Rozman ◽  
Danijela Semenic ◽  
Dragica Maja
Keyword(s):  
Regenerative Medicine ◽  
Platelet Gel

scholarly journals Role of Autologous Platelet Gel (APG) in Bone Healing: A Rabbit Study

2021 ◽  
Vol 11 (1) ◽  
pp. 395
Author(s):  
Antonio Scarano ◽  
Francesco Inchingolo ◽  
Biagio Rapone ◽  
Alberta Greco Lucchina ◽  
Erda Qorri ◽  
...  
Keyword(s):  
Critical Size ◽  
Bone Defects ◽  
New Bone Formation ◽  
Platelet Gel ◽  
Woven Bone ◽  
Rapid Healing ◽  
Rabbit Bone ◽  
Autologous Platelet ◽  
New Zealand Rabbits

Purpose: The aim of the present study is to evaluate the influence and efficacy of autologous platelets on bone regeneration in a rabbit defects model. Materials and Methods: A total of 12 critical size tibial defects were produced in six New Zealand rabbits: A total of six defects were filled with autologous platelet gel (APG) and six defects were maintained as untreated controls. No membranes were used to cover the bone osteotomies. The histology and histomorphometry were performed at four weeks on retrieved samples of both groups. Results: No complications were reported in any of the animals nor for the defects produced. A significantly higher lamellar and woven bone percentage was reported for the APG group with a lower level of marrow spaces (p < 0.05). Evidence of newly formed bone was found in the superficial portion of the bone defect of APG samples where no aspects of bone resorption were observed. Conclusions: The evidence of the present research revealed that APG increases new bone formation restricted to the cortical portion and induces more rapid healing in rabbit bone defects than in untreated defects.

The Role of Biomaterials and Scaffolds on Immune Responses in Regenerative Medicine: Macrophage Phenotype Modulation by Biomaterial Properties and Scaffold Architectures

2021 ◽  
Author(s):  
Ezgi Antmen ◽  
Nihal Engin Vrana ◽  
Vasif Hasirci
Keyword(s):  
Regenerative Medicine ◽  
Immune Responses ◽  
Macrophage Phenotype ◽  
Immune Reactions

Scaffolds are an integral part of the regenerative medicine field. The contact of biomaterials with tissue, as was clearly observed over the years, induces immune reactions in a material and...

Platelet gel: the “holy water” of regenerative medicine

2018 ◽  
Vol 14 (4) ◽  
pp. 201-202
Author(s):  
Andrea Piccin ◽  
Angela Maria Di Pierro ◽  
Luca Calabrese ◽  
Fabrizio Fontanella ◽  
Massimo Daves
Keyword(s):  
Regenerative Medicine ◽  
Platelet Gel ◽  
Holy Water

scholarly journals Stem Cell Therapy and Regenerative Medicine in Autoimmune Diseases

2021 ◽  
Author(s):  
Bhuvaneshwari Sampath ◽  
Priyadarshan Kathirvelu ◽  
Kavitha Sankaranarayanan
Keyword(s):  
Stem Cell ◽  
Immune System ◽  
Regenerative Medicine ◽  
Autoimmune Diseases ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Autoimmune Condition ◽  
Recent Trends

The role of immune system in our body is to defense against the foreign bodies. However, if the immune system fails to recognize self and non-self-cells in our body leads to autoimmune diseases. Widespread autoimmune diseases are rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, type 1 diabetes, and more yet to be added to the list. This chapter discusses about how stem cell-based therapies and advancement of regenerative medicine endow with novel treatment for autoimmune diseases. Furthermore, in detail, specific types of stem cells and their therapeutic approach for each autoimmune condition along with their efficiency to obtain desired results are discussed. Ultimately, this chapter describes the recent trends in treating autoimmune diseases effectively using advanced stem cell research.

Sign in / Sign up

Export Citation Format

Share Document