scholarly journals Perioperative Organ Protection in Cardiac Surgery

Author(s):  
Maria Carmona ◽  
Matheus Vane ◽  
Luiz Malbouisso
2014 ◽  
Vol 186 (1) ◽  
pp. 207-216 ◽  
Author(s):  
Nur A.B. Haji Mohd Yasin ◽  
Peter Herbison ◽  
Pankaj Saxena ◽  
Slavica Praporski ◽  
Igor E. Konstantinov

2002 ◽  
Vol 124 (2) ◽  
pp. 387-391 ◽  
Author(s):  
S. Martens ◽  
M. Dietrich ◽  
M. Doss ◽  
G. Wimmer-Greinecker ◽  
A. Moritz

2014 ◽  
Vol 20 (2) ◽  
pp. 157-165 ◽  
Author(s):  
Dominique A. Bettex ◽  
Patrick M. Wanner ◽  
Marco Bosshart ◽  
Christian Balmer ◽  
Walter Knirsch ◽  
...  

Author(s):  
Radosław Gocoł ◽  
Damian Hudziak ◽  
Jarosław Bis ◽  
Konrad Mendrala ◽  
Łukasz Morkisz ◽  
...  

Hypothermia is defined as a decrease in body core temperature to below 35°C. In cardiac surgery, four stages of hypothermia are distinguished: mild, moderate, deep, and profound. The organ protection offered by deep hypothermia (DH) enables safe circulatory arrest as a prerequisite to carrying out cardiac surgical intervention. In adult cardiac surgery, DH is mainly used in aortic arch surgery, surgical treatment of pulmonary embolism, and acute type-A aortic dissection interventions. In surgery treating congenital defects, DH is used to assist aortic arch reconstructions, hypoplastic left heart syndrome interventions, and for multi-stage treatment of infants with a single heart ventricle during the neonatal period. However, it should be noted that a safe duration of circulatory arrest in DH for the central nervous system is 30 to 40 min at most and should not be exceeded to prevent severe neurological adverse events. Personalized therapy for the patient and adequate blood temperature monitoring, glycemia, hematocrit, pH, and cerebral oxygenation is a prerequisite and indispensable part of DH.


Perfusion ◽  
2017 ◽  
Vol 32 (6) ◽  
pp. 446-453 ◽  
Author(s):  
Kyriakos Anastasiadis ◽  
Polychronis Antonitsis ◽  
Apostolos Deliopoulos ◽  
Helena Argiriadou

Background: Cardiac surgery is, by definition, a “non-physiologic” intervention associated with systemic adverse effects. Despite advances in surgical technique, cardiopulmonary bypass (CPB) technology as well as anaesthesia management and patient care, there is still significant morbidity and subsequent mortality. Aim: We consider that the contemporary demand for further improving patient outcome mandates the upgrade from optimal perfusion during the procedure as the gold standard to the concept of a “more physiologic” cardiac surgery. Our policy is a multidisciplinary perioperative strategy based on goal-directed perfusion throughout surgery incorporating in-line monitoring. This translates to “prevent rather than correct” malperfusion through real-time adjustment rather than correction of derangement detected late by incremental evaluation. Method: The strategy is based on continuous monitoring of cardiac index, SvO2, DO2i, DO2i/VCO2i and rSO2. Data acquisition is followed by action when needed; this includes stepwise: transfusion, increase of cardiac output and initiation of inotropic/vasoactive support. Moreover, implementation of minimally invasive extracorporeal circulation (MiECC) is considered as a fundamental component of physiologic perfusion when on-CPB, providing improved circulatory support and end-organ protection. Conclusion: We consider that, with this strategy which establishes optimal perfusion perioperatively, we attain the goal of a “more physiologic” cardiac surgery.


JAMA ◽  
1966 ◽  
Vol 195 (5) ◽  
pp. 356-361 ◽  
Author(s):  
J. B. McClenahan
Keyword(s):  

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