scholarly journals Paradigm Shift in the Concept of Hormonal Milieu of Prostate Cancer

10.5772/25625 ◽  
2011 ◽  
Author(s):  
Tsutomu Nishiyama
Keyword(s):  
Prostate Cancer ◽  
Paradigm Shift ◽  
Hormonal Milieu

TRUS–MRI image registration: a paradigm shift in the diagnosis of significant prostate cancer

2013 ◽  
Vol 38 (6) ◽  
pp. 1447-1463 ◽  
Author(s):  
F. Cornud ◽  
L. Brolis ◽  
N. Barry Delongchamps ◽  
D. Portalez ◽  
B. Malavaud ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Image Registration ◽  
Paradigm Shift ◽  
Mri Image

scholarly journals Docetaxel in prostate cancer: a familiar face as the new standard in a hormone-sensitive setting

2017 ◽  
Vol 9 (5) ◽  
pp. 307-318 ◽  
Author(s):  
Javier Puente ◽  
Enrique Grande ◽  
Ana Medina ◽  
Pablo Maroto ◽  
Nuria Lainez ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Paradigm Shift ◽  
Distant Metastases ◽  
Tumor Burden ◽  
Potential Toxicity ◽  
Ablation Therapy ◽  
Androgen Ablation ◽  
Hormone Sensitive ◽  
Androgen Ablation Therapy

The increasing knowledge of prostate cancer is leading to many questions about its natural history and to reconsider conventional therapeutic strategies. Androgen ablation therapy has been the standard therapy in the advanced setting. Although docetaxel has demonstrated increased survival in patients with metastatic prostate cancer who had progressed to hormone treatments, due to its potential toxicity the role of chemotherapy has been relegated to patients who were symptomatic or who had high tumor burden. Several studies have assessed whether docetaxel could have a role in hormone-sensitive disease or even in earlier stages with no distant metastases. In the CHAARTED and STAMPEDE studies, docetaxel provides an unprecedented increase in overall survival (OS). This review summarizes the evidence behind the paradigm shift to strengthening docetaxel as a new standard of treatment that prolongs survival in earlier stages of prostate cancer.

scholarly journals Cancer immunotherapy: a paradigm shift for prostate cancer treatment

2012 ◽  
Vol 9 (7) ◽  
pp. 376-385 ◽  
Author(s):  
Dev Karan ◽  
Jeffrey M. Holzbeierlein ◽  
Peter Van Veldhuizen ◽  
J. Brantley Thrasher
Keyword(s):  
Prostate Cancer ◽  
Cancer Treatment ◽  
Cancer Immunotherapy ◽  
Paradigm Shift ◽  
Prostate Cancer Treatment

scholarly journals A paradigm shift from anatomic to functional and molecular imaging in the detection of recurrent prostate cancer

2014 ◽  
Vol 10 (3) ◽  
pp. 457-474 ◽  
Author(s):  
Nicholas G Zaorsky ◽  
Kosj Yamoah ◽  
Madhukar L Thakur ◽  
Edouard J Trabulsi ◽  
Timothy N Showalter ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Molecular Imaging ◽  
Paradigm Shift ◽  
Recurrent Prostate Cancer
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