scholarly journals Tolerogenic Dendritic Cells for Therapy of Immune-Mediated Inflammatory Diseases

10.5772/25329 ◽  
2012 ◽  
Author(s):  
Urban vajger ◽  
Borut trukelj
Keyword(s):  
Dendritic Cells ◽  
Inflammatory Diseases ◽  
Tolerogenic Dendritic Cells ◽  
Immune Mediated

Tolerogenic Dendritic Cells in Autoimmunity and Inflammatory Diseases

2021 ◽  
Vol 42 (1) ◽  
pp. 59-75
Author(s):  
Octavio Morante-Palacios ◽  
Federico Fondelli ◽  
Esteban Ballestar ◽  
Eva M. Martínez-Cáceres
Keyword(s):  
Dendritic Cells ◽  
Inflammatory Diseases ◽  
Tolerogenic Dendritic Cells

scholarly journals Probiotic-Induced Tolerogenic Dendritic Cells: A Novel Therapy for Inflammatory Bowel Disease?

2021 ◽  
Vol 22 (15) ◽  
pp. 8274
Author(s):  
Shaghayegh Baradaran Ghavami ◽  
Hamid Asadzadeh Aghdaei ◽  
Dario Sorrentino ◽  
Shabnam Shahrokh ◽  
Maryam Farmani ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Treatment Options ◽  
Novel Therapy ◽  
Additional Tool ◽  
Tolerogenic Dendritic Cells ◽  
Immune Mediated ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Inflammatory bowel diseases (IBDs) are immune-mediated, chronic relapsing diseases with a rising prevalence worldwide in both adult and pediatric populations. Treatment options for immune-mediated diseases, including IBDs, are traditional steroids, immunomodulators, and biologics, none of which are capable of inducing long-lasting remission in all patients. Dendritic cells (DCs) play a fundamental role in inducing tolerance and regulating T cells and their tolerogenic functions. Hence, modulation of intestinal mucosal immunity by DCs could provide a novel, additional tool for the treatment of IBD. Recent evidence indicates that probiotic bacteria might impact immunomodulation both in vitro and in vivo by regulating DCs’ maturation and producing tolerogenic DCs (tolDCs) which, in turn, might dampen inflammation. In this review, we will discuss this evidence and the mechanisms of action of probiotics and their metabolites in inducing tolDCs in IBDs and some conditions associated with them.

HIV-Antigens Charged on Phosphorus Dendrimers as Tools for Tolerogenic Dendritic Cells-Based Immunotherapy

2014 ◽  
Vol 21 (16) ◽  
pp. 1898-1909 ◽  
Author(s):  
Enrique Vacas-Cordoba ◽  
Hugo Bastida ◽  
Marjorie Pion ◽  
Aurelien Hameau ◽  
Maksim Ionov ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Tolerogenic Dendritic Cells

scholarly journals 4CPS-329 Do patients with immune mediated inflammatory diseases think they know their medication?

2021 ◽  
Author(s):  
A Melgarejo-Ortuño ◽  
RM Romero Jiménez ◽  
E Chamorro De Vega ◽  
A Ais Larisgoitia ◽  
ME Lobato Matilla ◽  
...  
Keyword(s):  
Inflammatory Diseases ◽  
Immune Mediated
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