scholarly journals Endoscopic Resection of Early Gastric Cancer

10.5772/24614 ◽  
2011 ◽  
Author(s):  
Sang Gyun
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Endoscopic Resection

Comparison of endoscopic resection and gastrectomy for the treatment of early gastric cancer: a meta-analysis

2015 ◽  
Vol 30 (9) ◽  
pp. 3673-3683 ◽  
Author(s):  
Fan-Sheng Meng ◽  
Zhao-Hong Zhang ◽  
Ya-Mei Wang ◽  
Lin Lu ◽  
Jin-Zhou Zhu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Endoscopic Resection ◽  
Meta Analysis

scholarly journals Clinicopathological significance of primitive phenotypes in early gastric cancer with differentiated histology

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Zhi-Yi Zhou ◽  
Jie Sun ◽  
Qing Guo ◽  
Hai-Bin Zhao ◽  
Zhi-Hua Zhou
Keyword(s):  
Gastric Cancer ◽  
Risk Factor ◽  
Early Gastric Cancer ◽  
Endoscopic Resection ◽  
Independent Risk Factor ◽  
Lymphatic Invasion ◽  
Clinicopathological Features ◽  
Surgical Operation ◽  
Tissue Sections ◽  
Clinicopathological Significance

Abstract Background Certain gastric cancers exhibit some primitive phenotypes, which may indicate a high malignancy. In histologically differentiated early gastric cancer (EGC), the presence and the clinicopathological significance of the primitive phenotype remain unclear. Methods Using immunohistochemical staining we detected the expression of three primitive phenotypic markers SALL4, Glypican-3(GPC3), and AFP in whole tissue sections of differentiated EGC (gastrectomy specimens, n = 302). For those cases with primitive phenotypes, we analyzed their clinicopathological features and evaluated whether the criteria for endoscopic resection were met. Results We found that 9.3% (28/302) of all differentiated EGC cases have primitive phenotypes, and most of these cases (25/28) exhibit a histomorphology similar to conventional differentiated EGC. Patients with primitive phenotypes had a deeper invasion, a higher rate of ulcer and lymphatic invasion than cases without primitive phenotype. Moreover, patients with primitive phenotypes displayed a significantly higher frequency of LNM than those without (57.1% vs 8.8%, P < 0.001). Multivariate analysis revealed that presence of primitive phenotypes was an independent risk factor for LNM (P = 0.001, HR 6.977, 95% CI: 2.199–22.138). Interestingly, we found 2 cases with primitive phenotypes developed LNM, and they both met the expanded indications of endoscopic resection for differentiated EGC. Conclusions A small number of differentiated EGC have primitive phenotypes, which were closely related to LNM and were an independent risk factor for LNM. Given its highly aggressive behavior, differentiated EGC with primitive phenotypes should be evaluated with stricter criteria before endoscopic resection, or considered to give an additional surgical operation after endoscopic resection.

Long-term clinical outcomes of endoscopic resection for early gastric cancer

2014 ◽  
Vol 29 (5) ◽  
pp. 1223-1230 ◽  
Author(s):  
Jeongmin Choi ◽  
Sang Gyun Kim ◽  
Jong Pil Im ◽  
Joo Sung Kim ◽  
Hyun Chae Jung
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Clinical Outcomes ◽  
Endoscopic Resection

scholarly journals Endoscopic Resection Versus Surgical Resection for Early Gastric Cancer

Medicine ◽  
2015 ◽  
Vol 94 (43) ◽  
pp. e1649 ◽  
Author(s):  
Weili Sun ◽  
Xiao Han ◽  
Siyuan Wu ◽  
Chuanhua Yang
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Surgical Resection ◽  
Endoscopic Resection

Long-term outcomes after noncurative endoscopic resection of early gastric cancer: the optimal time for additional endoscopic treatment

2018 ◽  
Vol 87 (4) ◽  
pp. 1003-1013.e2 ◽  
Author(s):  
Mi Young Jeon ◽  
Jun Chul Park ◽  
Kyu Yeon Hahn ◽  
Sung Kwan Shin ◽  
Sang Kil Lee ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Endoscopic Resection ◽  
Endoscopic Treatment ◽  
Optimal Time ◽  
Long Term Outcomes

scholarly journals A multicenter retrospective study of endoscopic resection for early gastric cancer

2006 ◽  
Vol 9 (4) ◽  
pp. 262-270 ◽  
Author(s):  
Ichiro Oda ◽  
Daizo Saito ◽  
Masahiro Tada ◽  
Hiroyasu Iishi ◽  
Satoshi Tanabe ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Retrospective Study ◽  
Early Gastric Cancer ◽  
Endoscopic Resection
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