scholarly journals The Impact of Polycystic Ovarian Syndrome on Gestational Diabetes

10.5772/23795 ◽  
2011 ◽  
Author(s):  
Stefanie Aust ◽  
Johannes Ott
Keyword(s):  
Gestational Diabetes ◽  
Polycystic Ovarian Syndrome ◽  
The Impact ◽  
Ovarian Syndrome

The impact of insulin resistance and hyperandrogenemia on polysomnographic variables in obese adolescents with polycystic ovarian syndrome

2011 ◽  
Vol 16 (1) ◽  
pp. 169-175 ◽  
Author(s):  
Gideon de Sousa ◽  
Bernhard Schlüter ◽  
Dirk Buschatz ◽  
Thomas Menke ◽  
Eckardt Trowitzsch ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Polycystic Ovarian Syndrome ◽  
Obese Adolescents ◽  
The Impact ◽  
Ovarian Syndrome

scholarly journals Metformin throughout Pregnancy in Women with Polycystic Ovary Syndrome: Safety and Advantages

2011 ◽  
Vol 2 (2) ◽  
pp. 61-64 ◽  
Author(s):  
Bharti Bansal ◽  
Rutvij Jay Dalal ◽  
P Palshetkar Nandita ◽  
D Pai Hrishikesh ◽  
Takhtani Manisha ◽  
...  
Keyword(s):  
Gestational Diabetes ◽  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Maternal Complications ◽  
Ovary Syndrome ◽  
Trimester Abortion ◽  
Metformin Therapy ◽  
High Incidence ◽  
Ovarian Syndrome ◽  
In Pregnancy

ABSTRACT Objective To study the incidence of spontaneous abortions, congenital malformations, neonatal and maternal hypoglycemia after metformin therapy in pregnancy. Design Prospective study. Setting Outpatient. Patient(s) 56 women previously oligomenorrheic, nondiabetic women with polycystic ovarian syndrome, who conceived while on metformin. Intervention(s) Metformin 1 to 1.5 gm/day throughout pregnancy. Main outcome Incidence of 1st trimester abortions, gestational diabetes, teratogenicity and maternal complications, like gastritis and hypoglycemia. Results On metformin, the incidence of 1st trimester abortion was 11% and the incidence of gestational diabetes was 7%, which is much lower than the incidence otherwise cited for PCOS women. No major congenital abnormalities were observed. Conclusion Metformin therapy in pregnancy reduces the otherwise high incidence of 1st trimester abortions, and gestational diabetes in PCOS women is tolerated well and is not found to be teratogenic.

scholarly journals Polycystic ovarian syndrome and pregnancy outcome

2017 ◽  
Vol 6 (9) ◽  
pp. 3804
Author(s):  
Chaitra Shivananjaiah ◽  
Abinaya Kannan ◽  
Mridula Devi ◽  
. Jayanthi ◽  
Satish D. ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Gestational Age ◽  
Polycystic Ovarian Syndrome ◽  
Mode Of Delivery ◽  
Fetal Outcome ◽  
Hypertensive Disorder ◽  
Ovarian Syndrome ◽  
In Pregnancy

Background: Polycystic ovarian syndrome (PCOS) in the present generation is a very common reproductive disorder and the prevalence is on the rise. It is associated with typical features such as insulin resistance, hyperandrogenemia and obesity which has deep implications on the pregnancy outcomes as well as a long-term health of the woman.Methods: Prospective comparative study performed over 200 pregnant women in the ESIC medical college, Bangalore. 100 women diagnosed with PCOS were compared with that of 100 normal women. The method of conception in pcos was recorded. maternal outcome in the form of abortion, gestational diabetes mellitus, hypertensive disorder in pregnancy, mode of delivery, intrapartum and postpartum complication. Fetal outcome in the form preterm delivery, small-for-gestational-age (SGA) infants, large-for-gestational-age infants, apgar at 5 minute and admission to NICU.Results: Of the 100 women who were diagnosed with PCOS, 62 had spontaneous conception, 32 conceived with ovulation induction, 4 with artificial insemination and 2 needed IVF for conception. 18 women had spontaneous abortion, 58 were diagnosed with Gestational diabetes mellitus (GDM) predominantly between 24 – 28 weeks’ period of gestation, 16 women had hypertension complicating pregnancy. Fetal outcome in the form of preterm birth was noted in 14 patients, large for gestation was noted in 11 newborns, the rate of NICU admission was significantly higher in the PCOS women’s infants constituting 33%.Conclusions: The assistance needed for conception was significantly higher in women with PCOS. The complications associated with pregnancy such as spontaneous abortions, gestational diabetes, hypertensive disorder in pregnancy, preterm births, need of NICU care for the infants are much higher in women with PCOS.  Adult health education and the preconception diagnosis and appropriate management of PCOS is an important primary mode of prevention of these associated complications. 

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