scholarly journals Urinary Biomarkers in Glomerulonephritis

10.5772/23314 ◽  
2011 ◽  
Author(s):  
Sophie Ohlsson
Keyword(s):  
Urinary Biomarkers

Mass spectrometry based urinary biomarkers to distinguish non-significant from significant prostate cancer

2019 ◽  
Vol 18 (8) ◽  
pp. e3072
Author(s):  
M. Frantzi ◽  
M.C. Hupe ◽  
E. Gomez-Gomez ◽  
A. Blanca-Pedregosa ◽  
J. Valero Rosa ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Mass Spectrometry ◽  
Urinary Biomarkers

The need for vigilance: False-negative screening for adenylosuccinate lyase deficiency caused by deribosylation of urinary biomarkers

2013 ◽  
Vol 46 (18) ◽  
pp. 1899-1901 ◽  
Author(s):  
Jakub Krijt ◽  
Vaclava Skopova ◽  
Vaclava Adamkova ◽  
Renata Cermakova ◽  
Agnieszka Jurecka ◽  
...  
Keyword(s):  
False Negative ◽  
Urinary Biomarkers ◽  
Adenylosuccinate Lyase ◽  
Lyase Deficiency ◽  
Adenylosuccinate Lyase Deficiency

scholarly journals Grill Workers Exposure to Polycyclic Aromatic Hydrocarbons: Levels and Excretion Profiles of the Urinary Biomarkers

2020 ◽  
Vol 18 (1) ◽  
pp. 230
Author(s):  
Marta Oliveira ◽  
Sílvia Capelas ◽  
Cristina Delerue-Matos ◽  
Simone Morais
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Aromatic Hydrocarbons ◽  
High Performance ◽  
Principal Component ◽  
Fold Increase ◽  
Urinary Biomarkers ◽  
Analysis Model ◽  
Exposed Workers ◽  
Polycyclic Aromatic ◽  
The Impact

Grilling activities release large amounts of hazardous pollutants, but information on restaurant grill workers’ exposure to polycyclic aromatic hydrocarbons (PAHs) is almost inexistent. This study assessed the impact of grilling emissions on total workers’ exposure to PAHs by evaluating the concentrations of six urinary biomarkers of exposure (OHPAHs): naphthalene, acenaphthene, fluorene, phenanthrene, pyrene, and benzo(a)pyrene. Individual levels and excretion profiles of urinary OHPAHs were determined during working and nonworking periods. Urinary OHPAHs were quantified by high-performance liquid-chromatography with fluorescence detection. Levels of total OHPAHs (∑OHPAHs) were significantly increased (about nine times; p ≤ 0.001) during working comparatively with nonworking days. Urinary 1-hydroxynaphthalene + 1-hydroxyacenapthene and 2-hydroxyfluorene presented the highest increments (ca. 23- and 6-fold increase, respectively), followed by 1-hydroxyphenanthrene (ca. 2.3 times) and 1-hydroxypyrene (ca. 1.8 times). Additionally, 1-hydroxypyrene levels were higher than the benchmark, 0.5 µmol/mol creatinine, in 5% of exposed workers. Moreover, 3-hydroxybenzo(a)pyrene, biomarker of exposure to carcinogenic PAHs, was detected in 13% of exposed workers. Individual excretion profiles showed a cumulative increase in ∑OHPAHs during consecutive working days. A principal component analysis model partially discriminated workers’ exposure during working and nonworking periods showing the impact of grilling activities. Urinary OHPAHs were increased in grill workers during working days.

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