scholarly journals Modulation of Iron Metabolism and Hepcidin Release by HFE Mutations in Chronic Hemodialysis Patients: Pathophysiological and Therapeutic Implications

10.5772/22735 ◽  
2011 ◽  
Author(s):  
Elena Canavesi ◽  
Luca Valenti
Keyword(s):  
Iron Metabolism ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Therapeutic Implications ◽  
Hfe Mutations

scholarly journals HFE Mutations Modulate the Effect of Iron on Serum Hepcidin-25 in Chronic Hemodialysis Patients

2009 ◽  
Vol 4 (8) ◽  
pp. 1331-1337 ◽  
Author(s):  
Luca Valenti ◽  
Domenico Girelli ◽  
Giovanni Francesco Valenti ◽  
Annalisa Castagna ◽  
Giovanna Como ◽  
...  
Keyword(s):  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Serum Hepcidin ◽  
Hfe Mutations

scholarly journals The A736V TMPRSS6 polymorphism influences hepcidin and iron metabolism in chronic hemodialysis patients: TMPRSS6 and hepcidin in hemodialysis

2013 ◽  
Vol 14 (1) ◽  
Author(s):  
Serena Pelusi ◽  
Domenico Girelli ◽  
Raffaela Rametta ◽  
Natascia Campostrini ◽  
Carlo Alfieri ◽  
...  
Keyword(s):  
Iron Metabolism ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis

scholarly journals SP733CHANGES IN BIOIMPEDANCE ANALYSIS MEASURES IN CHRONIC HEMODIALYSIS PATIENTS DURING ONE YEAR

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii619-iii620
Author(s):  
Ruta Vaiciuniene ◽  
Irmante Stramaityte ◽  
Edita Ziginskiene ◽  
Vytautas Kuzminskis ◽  
Inga Arune Bumblyte
Keyword(s):  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Bioimpedance Analysis ◽  
One Year

Physical activity patterns in chronic hemodialysis patients: Comparison of dialysis and nondialysis days

2005 ◽  
Vol 15 (2) ◽  
pp. 217-224 ◽  
Author(s):  
Karen M. Majchrzak ◽  
Lara B. Pupim ◽  
Kong Chen ◽  
Cathi J. Martin ◽  
Sheila Gaffney ◽  
...  
Keyword(s):  
Physical Activity ◽  
Activity Patterns ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Physical Activity Patterns

scholarly journals Triage of Patients Suspected of COVID-19 in Chronic Hemodialysis: Eosinophil Count Differentiates Low and High Suspicion of COVID-19

2020 ◽  
Vol 10 (1) ◽  
pp. 4
Author(s):  
Romain Vial ◽  
Marion Gully ◽  
Mickael Bobot ◽  
Violaine Scarfoglière ◽  
Philippe Brunet ◽  
...  
Keyword(s):  
Predictive Value ◽  
Eosinophil Count ◽  
Characteristic Curve ◽  
Final Analysis ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Screening Methods ◽  
Dialysis Session ◽  
Diagnostic Study ◽  
Rt Pcr

Background: Daily management to shield chronic dialysis patients from SARS-CoV-2 contamination makes patient care cumbersome. There are no screening methods to date and a molecular biology platform is essential to perform RT-PCR for SARS-CoV-2; however, accessibility remains poor. Our goal was to assess whether the tools routinely used to monitor our hemodialysis patients could represent reliable and quickly accessible diagnostic indicators to improve the management of our hemodialysis patients in this pandemic environment. Methods: In this prospective observational diagnostic study, we recruited patients from La Conception hospital. Patients were eligible for inclusion if suspected of SARS-CoV-2 infection when arriving at our center for a dialysis session between March 12th and April 24th 2020. They were included if both RT-PCR result for SARS-CoV-2 and cell blood count on the day that infection was suspected were available. We calculated the area under the curve (AUC) of the receiver operating characteristic curve. Results: 37 patients were included in the final analysis, of which 16 (43.2%) were COVID-19 positive. For the day of suspected COVID-19, total leukocytes were significantly lower in the COVID-19 positive group (4.1 vs. 7.4 G/L, p = 0.0072) and were characterized by lower neutrophils (2.7 vs. 5.1 G/L, p = 0.021) and eosinophils (0.01 vs. 0.15 G/L, p = 0.0003). Eosinophil count below 0.045 G/L identified SARS-CoV-2 infection with AUC of 0.9 [95% CI 0.81—1] (p < 0.0001), sensitivity of 82%, specificity of 86%, a positive predictive value of 82%, a negative predictive value of 86% and a likelihood ratio of 6.04. Conclusions: Eosinophil count enables rapid routine screening of symptomatic chronic hemodialysis patients suspected of being COVID-19 within a range of low or high probability.

scholarly journals Age and multimorbidities as poor prognostic factors for COVID-19 in hemodialysis: a Lebanese national study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Mabel Aoun ◽  
Rabab Khalil ◽  
Walid Mahfoud ◽  
Haytham Fatfat ◽  
Line Bou Khalil ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Coronary Artery Disease ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Death Rate ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
National Study ◽  
Artery Disease

Abstract Background Hemodialysis patients with COVID-19 have been reported to be at higher risk for death than the general population. Several prognostic factors have been identified in the studies from Asian, European or American countries. This is the first national Lebanese study assessing the factors associated with SARS-CoV-2 mortality in hemodialysis patients. Methods This is an observational study that included all chronic hemodialysis patients in Lebanon who were tested positive for SARS-CoV-2 from 31st March to 1st November 2020. Data on demographics, comorbidities, admission to hospital and outcome were collected retrospectively from the patients’ medical records. A binary logistic regression analysis was performed to assess risk factors for mortality. Results A total of 231 patients were included. Mean age was 61.46 ± 13.99 years with a sex ratio of 128 males to 103 females. Around half of the patients were diabetics, 79.2% presented with fever. A total of 115 patients were admitted to the hospital, 59% of them within the first day of diagnosis. Hypoxia was the major reason for hospitalization. Death rate was 23.8% after a median duration of 6 (IQR, 2 to 10) days. Adjusted regression analysis showed a higher risk for death among older patients (odds ratio = 1.038; 95% confidence interval: 1.013, 1.065), patients with heart failure (odds ratio = 4.42; 95% confidence interval: 2.06, 9.49), coronary artery disease (odds ratio = 3.27; 95% confidence interval: 1.69, 6.30), multimorbidities (odds ratio = 1.593; 95% confidence interval: 1.247, 2.036), fever (odds ratio = 6.66; 95% confidence interval: 1.94, 27.81), CRP above 100 mg/L (odds ratio = 4.76; 95% confidence interval: 1.48, 15.30), and pneumonia (odds ratio = 19.18; 95% confidence interval: 6.47, 56.83). Conclusions This national study identified older age, coronary artery disease, heart failure, multimorbidities, fever and pneumonia as risk factors for death in patients with COVID-19 on chronic hemodialysis. The death rate was comparable to other countries and estimated at 23.8%.

scholarly journals Physical activity in Sahara Moroccan hemodialysis patients

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
A. Bahadi ◽  
H. Lagtarna ◽  
S. Benbria ◽  
Y. Zajjari ◽  
D. Elkabbaj ◽  
...  
Keyword(s):  
Physical Activity ◽  
Hemodialysis Patients ◽  
Education Level ◽  
Chronic Hemodialysis ◽  
Biological Data ◽  
New Approach ◽  
Male Predominance ◽  
Low Education ◽  
Reduced Physical Activity ◽  
A Prospective Study

Abstract Objective The evaluation of physical activity for chronic hemodialysis patients is a new approach for patient global care. The objective of this work is to evaluate the physical activity in chronic hemodialysis patients and identify the risk factors associated with reduced physical activity. This is a prospective study for 6 months including 150 chronic hemodialysis patients in the Guelmim-Oued Noun Regionin Moroccan Sahara. We use Baecke's survey, translated and validated in Arabic local language. The socio-demographic, clinical, and biological data were completed during the interrogation and from the medical records of the patients. Results The mean age of our patients was 54.6 ± 16.4 years, with male predominance (59%). Most patients have a low education level and 60% were illiterate. Hypertension was found in 54% of our patients, diabetes in 39%, and cardiovascular disease in 10% of patients. Low Physical activity was associated with gender (OR = 4.05), age (OR = 1.03) and high education level (OR = 0.2). Our work has met the various pre-established objectives, however other more specific studies must be conducted to better characterize the profile of physical activity in chronic hemodialysis patients.

scholarly journals POS-531 LIPID PROFILE AND CARDIOVASCULAR RISK IN CHRONIC HEMODIALYSIS PATIENTS

2021 ◽  
Vol 6 (4) ◽  
pp. S231
Author(s):  
I. Nasri ◽  
M. Khadhar ◽  
S. Bouassida ◽  
R. Lazzez ◽  
S. Agrebi ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Lipid Profile ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis
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