scholarly journals Manufacture, Structure Confirmation and Quality Control of the Chiral Drugs

10.5772/22715 ◽  
2011 ◽  
Author(s):  
Zhang Zhen ◽  
Bi Kaishu
Keyword(s):  
Quality Control ◽  
Chiral Drugs ◽  
Structure Confirmation

scholarly journals Research progress of chiral ligand exchange stationary phases in the enantiomer resolution

2021 ◽  
Vol 271 ◽  
pp. 04020
Author(s):  
Hui Bai
Keyword(s):  
Quality Control ◽  
Ligand Exchange ◽  
Stationary Phases ◽  
Research Progress ◽  
Chiral Ligand ◽  
Enantiomeric Resolution ◽  
Chiral Drugs ◽  
Enantiomer Resolution ◽  
Chiral Ligand Exchange

The structure of chiral drugs contains at least one asymmetric center. When the enantiomers act on the human body, they are recognized by chiral receptors and enzymes in vivo, which will show different physiological effects and even adverse reactions. Therefore, it is very important for the development of chiral pharmacy to obtain chiral enantiomers with a single configuration by racemic resolution. Some general impurities will be introduced in the production of chiral drugs, thus the detection of impurities is also a crucial step in the quality control of chiral medicines. The chiral ligand exchange stationary phase has a strong recognition effect on enantiomer analytes with multiple chelating sites, and is very suitable for the separation and control of biological samples such as amino acids. In this work, the development of chiral ligand exchange stationary phases in enantiomeric resolution is reviewed, which is expected to provide a basis for the quality control of complex chiral drug components.

Health communication ethics and CDC quality-control guidelines for information

2003 ◽  
Vol 118 (3) ◽  
pp. 193-196 ◽  
Author(s):  
Jeffrey W McKenna ◽  
Terry F Pechacek ◽  
Donna F Stroup
Keyword(s):  
Quality Control ◽  
Health Communication ◽  
Communication Ethics

Quality control and the medical record

1971 ◽  
Vol 127 (1) ◽  
pp. 101-105 ◽  
Author(s):  
L. L. Weed
Keyword(s):  
Quality Control ◽  
Medical Record

Metacognitively guided retrieval and report (META-RAR): Quality control processes in recall

2009 ◽  
Author(s):  
Morris Goldsmith ◽  
Larry L. Jacoby ◽  
Vered Halamish ◽  
Christopher N. Wahlheim
Keyword(s):  
Quality Control ◽  
Control Processes

Quality control

1956 ◽  
Vol 27 (106) ◽  
pp. 89
Author(s):  
N.R. Bedford
Keyword(s):  
Quality Control
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