scholarly journals Clinical Application of Image-Guided Iodine-125 Seed Implantation Therapy in Patients with Advanced Pancreatic Cancer

10.5772/22448 ◽  
2011 ◽  
Author(s):  
Wang Zhongmin ◽  
Chen Kemi
Keyword(s):  
Pancreatic Cancer ◽  
Clinical Application ◽  
Advanced Pancreatic Cancer ◽  
Seed Implantation ◽  
Image Guided ◽  
Iodine 125

Clinical efficacy of CT-guided iodine-125 seed implantation therapy in patients with advanced pancreatic cancer

2010 ◽  
Vol 20 (7) ◽  
pp. 1786-1791 ◽  
Author(s):  
Wang Zhongmin ◽  
Liu Yu ◽  
Liu Fenju ◽  
Chen Kemin ◽  
Huang Gang
Keyword(s):  
Pancreatic Cancer ◽  
Clinical Efficacy ◽  
Advanced Pancreatic Cancer ◽  
Ct Guided ◽  
Seed Implantation ◽  
Iodine 125

AB009. S009. Effect of endoscopic iodine 125 seeds brachytherapy on advanced pancreatic cancer: experience of single center

2018 ◽  
Vol 1 (1) ◽  
pp. AB009-AB009
Author(s):  
Bin Xiao ◽  
Guo-Sheng Chen ◽  
Yun-Peng Peng ◽  
Kui-Rong Jiang ◽  
Yi Miao
Keyword(s):  
Pancreatic Cancer ◽  
Advanced Pancreatic Cancer ◽  
Single Center ◽  
Iodine 125 ◽  
Cancer Experience

Efficacy and Safety of CT-Guided I-125 Seed Implantation for Advanced Pancreatic Cancer: A Meta-Analysis

Brachytherapy ◽  
2017 ◽  
Vol 16 (3) ◽  
pp. S89
Author(s):  
Hao Wang ◽  
Haitao Wang ◽  
Xiaodong Huo ◽  
Bin Huo ◽  
Shude Chai ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Meta Analysis ◽  
Advanced Pancreatic Cancer ◽  
Efficacy And Safety ◽  
Ct Guided ◽  
Seed Implantation

scholarly journals Intensity-Modulated and Image-Guided Radiotherapy in Patients with Locally Advanced Inoperable Pancreatic Cancer after Preradiation Chemotherapy

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
M. Sinn ◽  
R. Ganeshan ◽  
R. Graf ◽  
U. Pelzer ◽  
J. M. Stieler ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Overall Survival ◽  
Locally Advanced ◽  
Advanced Pancreatic Cancer ◽  
Intensity Modulated Radiotherapy ◽  
Image Guided Radiotherapy ◽  
Image Guided ◽  
Intensity Modulated ◽  
Kaplan Meier ◽  
Median Dosage

Background. Radiotherapy (RT) in patients with pancreatic cancer is still a controversial subject and its benefit in inoperable stages of locally advanced pancreatic cancer (LAPC), even after induction chemotherapy, remains unclear. Modern radiation techniques such as image-guided radiotherapy (IGRT) and intensity-modulated radiotherapy (IMRT) may improve effectiveness and reduce radiotherapy-related toxicities.Methods. Patients with LAPC who underwent radiotherapy after chemotherapy between 09/2004 and 05/2013 were retrospectively analyzed with regard to preradiation chemotherapy (PRCT), modalities of radiotherapy, and toxicities. Progression-free (PFS) and overall survival (OS) were estimated by Kaplan-Meier curves.Results. 15 (68%) women and 7 men (median age 64 years; range 40–77) were identified. Median duration of PRCT was 11.1 months (range 4.3–33.0). Six patients (27%) underwent conventional RT and 16 patients (73%) advanced IMRT and IGRT; median dosage was 50.4 (range 9–54) Gray. No grade III or IV toxicities occurred. Median PFS (estimated from the beginning of RT) was 5.8 months, 2.6 months in the conventional RT group (conv-RT), and 7.1 months in the IMRT/IGRT group (P=0.029); median OS was 11.0 months, 4.2 months (conv-RT), and 14.0 months (IMRT/IGRT);P=0.141. Median RT-specific PFS for patients with prolonged PRCT>9 months was 8.5 months compared to 5.6 months for PRCT<9 months (P=0.293). This effect was translated into a significantly better median RT-specific overall survival of patients in the PRCT>9 months group, with 19.0 months compared to 8.5 months in the PRCT  <  9 months group (P=0.049).Conclusions. IGRT and IMRT after PRCT are feasible and effective options for patients with LAPC after prolonged preradiation chemotherapy.

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